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A Novel CNN Architecture for Alzheimer’s Disease Classification Using MRI Data

International Journal of Electrical and Computer Engineering (IJECE) · Vol. 15 No. 3 (2025)

DOI
10.11591/ijece.v15i3.pp3519-3526
ISSN
2722-2578, 2088-8708
Published
2025-06-01
Publisher
Institute of Advanced Engineering and Science
License
creativecommons.org/licenses/by-sa/4.0

Abstract

Accurate categorization of Alzheimer’s disease is crucial for medical diagnosis and the development of therapeutic strategies. Deep learning models have demonstrated significant potential in this endeavor, however, they frequently encounter difficulties because of the intricate and varied characteristics of Alzheimer’s disease. To tackle this difficulty, we suggest a new and innovative architecture for Alzheimer’s disease classification using MRI data. This design is named Res-BRNet, and it combines deep residual and boundary-based convolutional neural networks (CNNs). Res-BRNet utilizes a methodical fusion of boundary-focused procedures within adapted spatial and residual blocks. The spatial blocks retrieve information relating to uniformity, diversity, and boundaries of Alzheimer’s disease, although the residual blocks successfully capture texture differences at both local and global levels. We conducted a performance assessment of Res-BRNe. The Res-BRNet surpassed conventional CNN models, with outstanding levels of accuracy (99.22%). The findings indicate that Res-BRNet has promise as a tool for classifying Alzheimer’s disease, with the ability to enhance the precision and effectiveness of clinical diagnosis and treatment planning.

Collaboration network of the authors

26 authors · 95 co-authorship links · 38 across different organisations

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  • Zarqa University
  • Al-Ahliyya Amman University
  • Al-Balqa Applied University
  • Applied Science Private University
  • Hashemite University
  • Higher Colleges of Technology
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Hamza Abu OwidaAl-Ahliyya Amman University6
Jamal Al-NabulsiAl-Ahliyya Amman University4
Nidal M. TurabAl-Ahliyya Amman University4
Muhammad Saleh Al-AyyadAl-Ahliyya Amman University2
Ali Mohd AliAl-Ahliyya Amman University2
Mohammad R. HassanAl-Ahliyya Amman University2
Feras AlnaimatAl-Ahliyya Amman University2
Ashraf Al SharahAl-Balqa Applied University2
Ghayth AlMahadinAl-Ahliyya Amman University2
Ghassan SamaraZarqa University2
Mohammad AljaidiZarqa University2
Hussain Mohammed TurkiZarqa University2
Essam Al-DaoudZarqa University2
Raed AlazaidahZarqa University2
Mais Haj QasemZarqa University2
Zaher SalahHashemite University1
Esraa Abu ElsoudZarqa University1
Waleed T. Al-SitHigher Colleges of Technology1
Esraa AlhenawiZarqa University1
Fuad Sameh AlshraiedehZarqa University1
Nour Al HawamdehAl-Ahliyya Amman University1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

This record comes from Crossref (what the publisher deposited), because the journal's own OAI-PMH endpoint could not be harvested.

Metadata source: Crossref API (cadangan, berdasarkan ISSN) https://api.crossref.org/journals/2088-8708/works, first harvested 27 Okt 2026, last seen 27 Okt 2026.
Metadata as oai_dc, converted from Crossref
<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/"><dc:title>A Novel CNN Architecture for Alzheimer’s Disease Classification Using MRI Data</dc:title><dc:creator>Abuowaida, Suhaila</dc:creator><dc:creator>Mustafa, Zaid</dc:creator><dc:creator>Aburomman, Ahmad</dc:creator><dc:creator>Alshdaifat, Nawaf</dc:creator><dc:creator>Iqtait, Musab</dc:creator><dc:description>&lt;jats:p&gt;&amp;lt;p&amp;gt;Accurate categorization of Alzheimer’s disease is crucial for medical diagnosis&amp;lt;br /&amp;gt;and the development of therapeutic strategies. Deep learning models&amp;lt;br /&amp;gt;have demonstrated significant potential in this endeavor, however, they frequently&amp;lt;br /&amp;gt;encounter difficulties because of the intricate and varied characteristics&amp;lt;br /&amp;gt;of Alzheimer’s disease. To tackle this difficulty, we suggest a new and innovative&amp;lt;br /&amp;gt;architecture for Alzheimer’s disease classification using MRI data. This&amp;lt;br /&amp;gt;design is named Res-BRNet, and it combines deep residual and boundary-based&amp;lt;br /&amp;gt;convolutional neural networks (CNNs). Res-BRNet utilizes a methodical fusion&amp;lt;br /&amp;gt;of boundary-focused procedures within adapted spatial and residual blocks. The&amp;lt;br /&amp;gt;spatial blocks retrieve information relating to uniformity, diversity, and boundaries&amp;lt;br /&amp;gt;of Alzheimer’s disease, although the residual blocks successfully capture&amp;lt;br /&amp;gt;texture differences at both local and global levels. We conducted a performance&amp;lt;br /&amp;gt;assessment of Res-BRNe. The Res-BRNet surpassed conventional CNN models,&amp;lt;br /&amp;gt;with outstanding levels of accuracy (99.22%). The findings indicate that&amp;lt;br /&amp;gt;Res-BRNet has promise as a tool for classifying Alzheimer’s disease, with the&amp;lt;br /&amp;gt;ability to enhance the precision and effectiveness of clinical diagnosis and treatment&amp;lt;br /&amp;gt;planning.&amp;lt;/p&amp;gt;&lt;/jats:p&gt;</dc:description><dc:publisher>Institute of Advanced Engineering and Science</dc:publisher><dc:date>2025-06-01</dc:date><dc:type>info:eu-repo/semantics/article</dc:type><dc:format>application/pdf</dc:format><dc:identifier>https://doi.org/10.11591/ijece.v15i3.pp3519-3526</dc:identifier><dc:identifier>10.11591/ijece.v15i3.pp3519-3526</dc:identifier><dc:source>International Journal of Electrical and Computer Engineering (IJECE); Vol 15 No 3 (2025); 3519</dc:source><dc:source>2722-2578</dc:source><dc:source>2088-8708</dc:source><dc:relation>https://ijece.iaescore.com/index.php/IJECE/article/viewFile/37424/18300</dc:relation><dc:rights>http://creativecommons.org/licenses/by-sa/4.0</dc:rights></oai_dc:dc>