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Comparison of Asymmetric Dimethylarginine Levels Between Stages Three, Four, and Five Non-dialysis of Chronic Kidney Disease

ACTA MEDICA INDONESIANA · Vol. 48 No. 1 (2016)

ISSN
2338-2732, 0125-9326
Terbit
2016-09-19
Penerbit
The Indonesian Society of Internal Medicine
Bahasa
eng

Abstrak

Aim: to determine the differences of ADMA level between stages 3, 4, and 5 non-dialysis of chronic kidney disease (CKD) patients at Outpatient Nephrology Clinic, Dr. Soetomo Hospital. Methods: a cross-sectional study was conducted on stage 3, 4, and 5 non-dialysis CKD patients at Outpatient Nephrology Clinic, Dr. Soetomo Hospital, Surabaya from January to February 2015. Stages of CKD were determined based on GFR estimation according to 4-variable MDRD formula. Statistical analysis of differences in the levels of ADMA in three subject groups use one-way ANOVA test. Results:seventy-five patients were included in the study. Each group consisted of 25 patients stage 3, 4, and, 5 non-dialysis patients. Mean age of stage 3, stage 4, and stage 5 non-dialysis CKD patients were respectively 57.12 years, 54.80 years and 53.68 years. The mean levels of ADMA in stage 3, stage 4, and 5 were 0.62 (0.11) IU/mL, 0.72 (0.16) IU/mL, and 0.73 (0.18) IU/mL respectively. Analysis of the differences between the groups showed significant differences in ADMA levels (p=0.04), with the highest difference between stage 3 and stage 5. Conclusion:comparison of ADMA levels showed significant differences between CKD stages and the level tends to be higher along with increase severity of CKD stages.

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  • State University of Jakarta
  • State University of Semarang
  • Sebelas Maret University
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Rekan penulisOrganisasiArtikel bersama
Wadiyo WadiyoAfiliasi tidak diketahui4
Udi UtomoAfiliasi tidak diketahui4
Jiel Vayyad RamadhanState University of Jakarta1
Muhammad Ficky DuskarnaenAfiliasi tidak diketahui1
Via Tuhamah FauziastutiState University of Jakarta1
Chelsea Zaomi PondayuState University of Jakarta1
Mada Rekadarma SeptiandaState University of Jakarta1
Alma Dita Mia NarfaisAfiliasi tidak diketahui1
Gunarti Dwi LestariAfiliasi tidak diketahui1
Wiwin YulianingsihAfiliasi tidak diketahui1
Rahina NugrahaniState University of Semarang1
Slamet HaryonoState University of Semarang1
Eko HaryantoState University of Semarang1
Johan SutarjoAfiliasi tidak diketahui1
I wayan agus suardiana putraAfiliasi tidak diketahui1
Agus CahyonoAfiliasi tidak diketahui1
Ronald CandraAfiliasi tidak diketahui1
Widia EffendiAfiliasi tidak diketahui1
Meisera Fika LathifasariAfiliasi tidak diketahui1
Raafinsha RahmaniarAfiliasi tidak diketahui1
Sunarto SunartoSebelas Maret University1
Sostenes Mono TandililingAfiliasi tidak diketahui1
Suharto SuhartoAfiliasi tidak diketahui1
Yustin Rati AnugerahAfiliasi tidak diketahui1
Malarsih MalarsihAfiliasi tidak diketahui1
Puspa YuniAfiliasi tidak diketahui1
Treyanus HomklomAfiliasi tidak diketahui1
Hisom Jati PrasetyoAfiliasi tidak diketahui1
Ekomagrah WarsonoAfiliasi tidak diketahui1
gita mumtazahAfiliasi tidak diketahui1

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Sumber metadata: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc)
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	<dc:title xml:lang="en-US">Comparison of Asymmetric Dimethylarginine Levels  Between Stages Three, Four, and Five Non-dialysis of  Chronic Kidney Disease</dc:title>
	<dc:creator>Asmarawati, Tri P</dc:creator>
	<dc:creator>Widodo, Widodo</dc:creator>
	<dc:creator>Thaha, M</dc:creator>
	<dc:creator>Aditiawardana, Aditiawardana</dc:creator>
	<dc:creator>Mardiana, Nunuk</dc:creator>
	<dc:creator>Ardhany, Ardityo R</dc:creator>
	<dc:creator>Tjempakasari, Artaria</dc:creator>
	<dc:creator>Santoso, Djoko</dc:creator>
	<dc:creator>Pranawa, Pranawa</dc:creator>
	<dc:creator>Irwanadi, Chandra</dc:creator>
	<dc:subject xml:lang="en-US">chronic kidney disease</dc:subject>
	<dc:subject xml:lang="en-US">asymmetric dimethylarginine (ADMA)</dc:subject>
	<dc:subject xml:lang="en-US">cardiovascular disease</dc:subject>
	<dc:description xml:lang="en-US">Aim: to determine the differences of ADMA level between stages 3, 4, and 5 non-dialysis of chronic kidney disease (CKD) patients at Outpatient Nephrology Clinic, Dr. Soetomo Hospital. Methods: a cross-sectional study was conducted on stage 3, 4, and 5 non-dialysis CKD patients at Outpatient Nephrology Clinic, Dr. Soetomo Hospital, Surabaya from January to February 2015. Stages of CKD were determined based on GFR estimation according to 4-variable MDRD formula. Statistical analysis of differences in the levels of ADMA in three subject groups use one-way ANOVA test. Results:seventy-five patients were included in the study. Each group consisted of 25 patients stage 3, 4, and, 5 non-dialysis patients. Mean age of stage 3, stage 4, and stage 5 non-dialysis CKD patients were respectively 57.12 years, 54.80 years and 53.68 years. The mean levels of ADMA in stage 3, stage 4, and 5 were 0.62 (0.11) IU/mL, 0.72 (0.16) IU/mL, and 0.73 (0.18) IU/mL respectively. Analysis of the differences between the groups showed significant differences in ADMA levels (p=0.04), with the highest difference between stage 3 and stage 5. Conclusion:comparison of ADMA levels showed significant differences between CKD stages and the level tends to be higher along with increase severity of CKD stages.</dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2016-09-19</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/134</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 48 No. 1 (2016): Acta Medica Indonesiana; 28</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/134/126</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2016 Acta Medica Indonesiana - The Indonesian Journal of Internal Medicine</dc:rights>
</oai_dc:dc>