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The Relationship Between fragmented QRS Complexes (fQRS) and the Severity of Coronary Artery Lesion in Coronary Artery Disease: A Cross-sectional Study

ACTA MEDICA INDONESIANA · Vol. 54 No. 3 (2022)

ISSN
2338-2732, 0125-9326
Terbit
2022-09-24
Penerbit
The Indonesian Society of Internal Medicine
Bahasa
eng

Abstrak

Background: The severity of coronary artery lesion is commonly used as a predictor of mortality, major adverse cardiovascular event, and revascularization in coronary artery disease (CAD). Fragmented QRS complex (fQRS) is used as a marker of myocardial ischemia in patients with CAD. The relationship between the two should be studied further. The objective of this study was to determine the relationship between fQRS and the severity of coronary lesion in patients with CAD. Methods: A cross-sectional study was conducted at Cipto Mangunkusumo Hospital Jakarta. Secondary data were taken from 172 patients with CAD who underwent percutaneous coronary intervention (PCI) from January to June 2018 with total sampling. Patients were divided into two groups based on the existence of fQRS. Demographic, clinical, and corangiography characteristics (Gensini score, total vascular lesion, and vascular lesion significance) were studied. Data were analyzed using agreement test and chi-square. Results: fQRS was present in 94 subjects (54.6%). Bivariate analysis showed a significant difference between fQRS with mild-moderate Gensini score as well as mild-severe Gensini score (kappa = 0.721 and 0.820; p<0.001), fQRS with significant CAD (kappa = 0.670; p<0.001), and fQRS with multivessel CAD (kappa = 0.787; p<0.001). Conclusion: There is a significant relationship between fQRS and the degree of severity of coronary lesion in CAD patients.

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  • University of Indonesia
  • Institut Agama Islam Negeri Bone
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Sally Aman NasutionAfiliasi tidak diketahui8
Kuntjoro HarimurtiAfiliasi tidak diketahui6
Lugyanti SukrismanAfiliasi tidak diketahui5
Simon SalimAfiliasi tidak diketahui5
Muhammad YaminInstitut Agama Islam Negeri Bone4
Rudi PutrantoAfiliasi tidak diketahui4
Ikhwan RinaldiAfiliasi tidak diketahui4
Siti SetiatiAfiliasi tidak diketahui4
Evy YunihastutiAfiliasi tidak diketahui4
Hamzah ShatriAfiliasi tidak diketahui4
Yulianto YuliantoAfiliasi tidak diketahui3
Idrus AlwiAfiliasi tidak diketahui3
Arif MansjoerAfiliasi tidak diketahui3
Em YunirUniversity of Indonesia3
Pringgodigdo NugrohoAfiliasi tidak diketahui3
Annisa Puspitasari NachrowiAfiliasi tidak diketahui3
Nurul Inayah RahmaniAfiliasi tidak diketahui3
Rudy HidayatAfiliasi tidak diketahui3
Zahra Nuril AnwarAfiliasi tidak diketahui3
Sukamto KoesnoeAfiliasi tidak diketahui3
Alvina WidhaniAfiliasi tidak diketahui2
Anshari Saifuddin HasibuanAfiliasi tidak diketahui2
Dyah PurnamasariAfiliasi tidak diketahui2
Ni Made HustriniAfiliasi tidak diketahui2
Dono AntonoAfiliasi tidak diketahui2
Lusiani RusdiAfiliasi tidak diketahui2
Noto DwimartutieAfiliasi tidak diketahui2
Aru W SudoyoAfiliasi tidak diketahui1
Nata P Hardjo LugitoAfiliasi tidak diketahui1
Andree KurniawanAfiliasi tidak diketahui1
Rizki YaruntradhaniAfiliasi tidak diketahui1
Arini SetiawatiAfiliasi tidak diketahui1
T. Djumhana AtmakusumaAfiliasi tidak diketahui1
Karmel L TambunanAfiliasi tidak diketahui1
Shufrie EffendiAfiliasi tidak diketahui1
A.R. HarahapAfiliasi tidak diketahui1

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Sumber metadata: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">The Relationship Between fragmented QRS Complexes (fQRS) and the Severity of Coronary Artery Lesion  in Coronary Artery Disease: A Cross-sectional Study</dc:title>
	<dc:creator>Wijaya, Ika Prasetya</dc:creator>
	<dc:creator>Ginanjar, Eka</dc:creator>
	<dc:creator>Rachman, Andhika</dc:creator>
	<dc:creator>Aini, M Hafiz</dc:creator>
	<dc:subject xml:lang="en-US">coronary artery disease</dc:subject>
	<dc:subject xml:lang="en-US">fragmented QRS</dc:subject>
	<dc:subject xml:lang="en-US">Gensini score</dc:subject>
	<dc:description xml:lang="en-US">Background: The severity of coronary artery lesion is commonly used as a predictor of mortality, major adverse cardiovascular event, and revascularization in coronary artery disease (CAD). Fragmented QRS complex (fQRS) is used as a marker of myocardial ischemia in patients with CAD. The relationship between the two should be studied further. The objective of this study was to determine the relationship between fQRS and the severity of coronary lesion in patients with CAD. Methods: A cross-sectional study was conducted at Cipto Mangunkusumo Hospital Jakarta. Secondary data were taken from 172 patients with CAD who underwent percutaneous coronary intervention (PCI) from January to June 2018 with total sampling. Patients were divided into two groups based on the existence of fQRS. Demographic, clinical, and corangiography characteristics (Gensini score, total vascular lesion, and vascular lesion significance) were studied. Data were analyzed using agreement test and chi-square. Results: fQRS was present in 94 subjects (54.6%). Bivariate analysis showed a significant difference between fQRS with mild-moderate Gensini score as well as mild-severe Gensini score (kappa = 0.721 and 0.820; p&amp;lt;0.001), fQRS with significant CAD (kappa = 0.670; p&amp;lt;0.001), and fQRS with multivessel CAD (kappa = 0.787; p&amp;lt;0.001). Conclusion: There is a significant relationship between fQRS and the degree of severity of coronary lesion in CAD patients. </dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2022-09-24</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/1920</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 54 No. 3 (2022): Acta Medica Indonesiana; 349</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/1920/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2022 Eka Ginanjar</dc:rights>
</oai_dc:dc>