Melola Discovery

← Melola Discovery

Jurnal SINTA 1

Urease Levels and Gastritis Stage in Dyspeptic Patients

ACTA MEDICA INDONESIANA · Vol. 54 No. 1 (2022)

ISSN
2338-2732, 0125-9326
Terbit
2022-04-08
Penerbit
The Indonesian Society of Internal Medicine
Bahasa
eng

Abstrak

Background: Dyspepsia is a frequent main symptom of inpatients and outpatients scenario in Indonesia. However, the number of endoscopy facilities are still low, thus the use of non-invasive method to detect gastritis is necessary. We measured the relationship between urease levels and the stage of gastritis in dyspeptic adult patients. Methods: A cross-sectional study included outpatient dyspepsia patient from November 2018 to February 2019. We examined 14C-Urea Breath Test (UBT) and determined the stage of gastritis based on the Updated Sydney System classification. Results: The urease level of acute and chronic gastritis positive patients were higher than negative patients (p = 0.001, r = 0.353; p <0.0001, r = 0.433, respectively). The AUC value of 14C-UBT to detect acute, chronic, and atrophic gastritis are 0.889, 0.632 and 0.544, respectively. The best cut-off points of 14C-UBT to predict acute gastritis was ≥26.50δ‰ with sensitivity and specificity being 88.89% and 63.95%, respectively. Whereas the best cut-off points for chronic gastritis was ≥34.50δ‰ with 82.89% sensitivity, 63.16% specificity. As for atrophic gastritis, it showed very low AUC value, hence it is not a sufficient test modality to predict atrophic gastritis cases. Conclusion: 14C-UBT is sufficient for predicting acute or chronic gastritis but not for atrophic gastritis.

Kata kunci

Jaringan kolaborasi para penulis

40 penulis · 277 tautan kepenulisan bersama · menampilkan 40 yang paling banyak terhubung

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
  • Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Annisa Zahra MufidaAfiliasi tidak diketahui6
Dadang MakmunAfiliasi tidak diketahui5
Iswan A NusiAfiliasi tidak diketahui4
Siti SetiatiAfiliasi tidak diketahui3
Murdani AbdullahAfiliasi tidak diketahui3
Adityo SusiloAfiliasi tidak diketahui2
Cleopas Martin RumendeAfiliasi tidak diketahui2
Hamzah ShatriAfiliasi tidak diketahui2
Saskia Aziza NursyirwanAfiliasi tidak diketahui2
Amanda Pitarini UtariAfiliasi tidak diketahui2
Rudy HidayatAfiliasi tidak diketahui2
Nury NusdwinuringtyasAfiliasi tidak diketahui2
Aria KekalihAfiliasi tidak diketahui2
Agus Dwi SusantoAfiliasi tidak diketahui2
Siti Chandra WidjanantieAfiliasi tidak diketahui2
Maria Regina RachmawatiAfiliasi tidak diketahui2
Won Ah ChoiAfiliasi tidak diketahui2
Seong Woong KangAfiliasi tidak diketahui2
Achmad FauziAfiliasi tidak diketahui2
Radhiyatam MardhiyahAfiliasi tidak diketahui1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Urease Levels and Gastritis Stage in Dyspeptic Patients</dc:title>
	<dc:creator>Miftahussurur, Muhammad</dc:creator>
	<dc:creator>Putri, Chyntia Dewi Maharani</dc:creator>
	<dc:creator>Sugihartono, Titong</dc:creator>
	<dc:creator>Syam, Ari Fahrial</dc:creator>
	<dc:creator>Purbayu, Herry</dc:creator>
	<dc:creator>Priyantini, Diah</dc:creator>
	<dc:creator>Kahar, Hartono</dc:creator>
	<dc:creator>Rezkitha, Yudith Annisa Ayu</dc:creator>
	<dc:creator>Nusi, Iswan Abbas</dc:creator>
	<dc:creator>Setiawan, Poernomo Boedi</dc:creator>
	<dc:creator>Maimunah, Ummi</dc:creator>
	<dc:creator>Waskito, Langgeng Agung</dc:creator>
	<dc:creator>Kholili, Ulfa</dc:creator>
	<dc:creator>Widodo, Budi</dc:creator>
	<dc:creator>Vidyani, Amie</dc:creator>
	<dc:creator>Thamrin, Husin</dc:creator>
	<dc:creator>Siregar, Gontar Alamsyah</dc:creator>
	<dc:creator>I’tishom, Reny</dc:creator>
	<dc:creator>Uchida, Tomohisa</dc:creator>
	<dc:creator>Yamaoka, Yoshio</dc:creator>
	<dc:subject xml:lang="en-US">Dyspepsia</dc:subject>
	<dc:subject xml:lang="en-US">Gastritis severity</dc:subject>
	<dc:subject xml:lang="en-US">Urea Breath Test</dc:subject>
	<dc:subject xml:lang="en-US">Cancer</dc:subject>
	<dc:subject xml:lang="en-US">gastorenterology</dc:subject>
	<dc:description xml:lang="en-US">Background: Dyspepsia is a frequent main symptom of inpatients and outpatients scenario in Indonesia. However, the number of endoscopy facilities are still low, thus the use of non-invasive method to detect gastritis is necessary. We measured the relationship between urease levels and the stage of gastritis in dyspeptic adult patients. Methods: A cross-sectional study included outpatient dyspepsia patient from November 2018 to February 2019. We examined 14C-Urea Breath Test (UBT) and determined the stage of gastritis based on the Updated Sydney System classification. Results: The urease level of acute and chronic gastritis positive patients were higher than negative patients (p = 0.001, r = 0.353; p &amp;lt;0.0001, r = 0.433, respectively). The AUC value of 14C-UBT to detect acute, chronic, and atrophic gastritis are 0.889, 0.632 and 0.544, respectively. The best cut-off points of 14C-UBT to predict acute gastritis was ≥26.50δ‰ with sensitivity and specificity being 88.89% and 63.95%, respectively. Whereas the best cut-off points for chronic gastritis was ≥34.50δ‰ with 82.89% sensitivity, 63.16% specificity. As for atrophic gastritis, it showed very low AUC value, hence it is not a sufficient test modality to predict atrophic gastritis cases. Conclusion: 14C-UBT is sufficient for predicting acute or chronic gastritis but not for atrophic gastritis.</dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2022-04-08</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/1927</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 54 No. 1 (2022): Acta Medica Indonesiana; 42</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/1927/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2022 Muhammad Miftahussurur, Chyntia Dewi Maharani Putri, Titong Sugihartono, Herry Purbayu, Diah Priyantini, Hartono Kahar, Yudith Annisa Ayu Rezkitha, Iswan Abbas Nusi, Poernomo Boedi Setiawan, Ummi Maimunah, Langgeng Agung Waskito, Ulfa Kholili, Budi Widodo, Amie Vidyani, Husin Thamrin, Gontar Alamsyah Siregar, Reny I’tishom, Tomohisa Uchida, Yoshio Yamaoka</dc:rights>
</oai_dc:dc>