Vitamin D Levels in Pre-frail Older Adults and Its Correlation with Hand Grip Strength

Dwimartutie, Noto; Setiati, Siti; Tamin, Tirza Z; Prijanti, Ani Retno; Harahap, Alida R; Purnamasari, Dyah; Harimurti, Kuntjoro; Pramantara, I Dewa Putu

Jurnal SINTA 1

Vitamin D Levels in Pre-frail Older Adults and Its Correlation with Hand Grip Strength

ACTA MEDICA INDONESIANA · Vol. 55 No. 2 (2023)

ISSN: 2338-2732, 0125-9326
Terbit: 2023-07-28
Penerbit: The Indonesian Society of Internal Medicine
Bahasa: eng

Abstrak

Background: Vitamin D deficiency is frequent in older adults and associated with poor musculoskeletal function. The prevalence of pre-frailty is also high in older persons, who may proceed to a frail state. This study aimed to determine the vitamin D levels in pre-frail older adults and its correlation with hand grip strength. Methods: A cross-sectional study was conducted on older adults (age > 60 years) with a pre-frail condition who were visiting the outpatient geriatric clinic at Cipto Mangunkusumo Hospital in Jakarta, Indonesia. Serum levels of vitamin D, measured as 25(OH)D, were determined by enzyme-linked immunosorbent assay (ELISA), and hand grip strength was measured using a Jamar hydraulic dynamometer. Correlations between vitamin D levels and hand grip strength were evaluated by Spearman’s rank correlation coefficient. Multiple linear regression analysis was carried out to assess contribution of variables that influence hand grip strength. Results: Of 95 pre-frail older adults (mean age 70.08 ± 5.35 years), 67.4% were female, and the median vitamin D level was 17.91 (interquartile range/IQR 13.68–26.36) ng/mL. Overall, 11.6% of the participants had normal vitamin D levels, whereas 34.7% and 53.7% had insufficient and deficient levels, respectively. Females were more likely to have inadequacy of vitamin D than males. Those with vitamin D deficiency tended to have a higher body mass index (BMI) and lower vitamin D intake than normal levels. A significant correlation between serum vitamin D levels and hand grip strength was observed (r = 0.283; P = 0.006). After adjusting for age, comorbidities, nutritional status, functional status, BMI, protein intake, and sun exposure score, regression analysis between hand grip strength and vitamin D levels gave standard coefficient beta = 0.255 (P = 0.013). Conclusion: In this study, pre-frail older adults had a high proportion of deficient and insufficient vitamin D levels, and a significant correlation was found between serum vitamin D levels and hand grip strength.

Kata kunci

Jaringan kolaborasi para penulis

40 penulis · 299 tautan kepenulisan bersama · menampilkan 40 yang paling banyak terhubung

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

Institut Agama Islam Negeri Bone
University of Indonesia
Afiliasi tidak diketahui

Organisasi berbeda
Organisasi sama
Afiliasi tidak diketahui
Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel

Tampilkan sebagai tabel

Rekan penulis	Organisasi	Artikel bersama
Rahmi Istanti	Afiliasi tidak diketahui	13
Roza Mulyana	Afiliasi tidak diketahui	13
Muhammad Khifzhon Azwar	Afiliasi tidak diketahui	12
Rensa Rensa	Afiliasi tidak diketahui	11
Hamzah Shatri	Afiliasi tidak diketahui	10
Jessica Marsigit	Afiliasi tidak diketahui	9
Rudi Putranto	Afiliasi tidak diketahui	9
Nur Riviati	Afiliasi tidak diketahui	9
Imam Subekti	Afiliasi tidak diketahui	9
Idrus Alwi	Afiliasi tidak diketahui	8
Eka Dian Safitri	Afiliasi tidak diketahui	8
Pradana Soewondo	Afiliasi tidak diketahui	8
Aulia Rizka	Afiliasi tidak diketahui	7
Cleopas Martin Rumende	Afiliasi tidak diketahui	7
Siti Rizny F Saldi	Afiliasi tidak diketahui	7
Ikhwan Rinaldi	Afiliasi tidak diketahui	6
Eka Ginanjar	Afiliasi tidak diketahui	6
Evy Yunihastuti	Afiliasi tidak diketahui	5
Rudy Hidayat	Afiliasi tidak diketahui	5
Muhammad Yamin	Institut Agama Islam Negeri Bone	5
Aida Lydia	Afiliasi tidak diketahui	5
Eric Daniel Tenda	Afiliasi tidak diketahui	5
Iris Rengganis	Afiliasi tidak diketahui	5
Juferdy Kurniawan	Afiliasi tidak diketahui	5
Andhika Rachman	Afiliasi tidak diketahui	4
Em Yunir	University of Indonesia	4
Ika Prasetya Wijaya	Afiliasi tidak diketahui	4
Murdani Abdullah	Afiliasi tidak diketahui	4
Dicky Levenus Tahapary	Afiliasi tidak diketahui	4
Sally Aman Nasution	Afiliasi tidak diketahui	4
Sally A Nasution	Afiliasi tidak diketahui	3
Arif Mansjoer	Afiliasi tidak diketahui	3

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) http://www.actamedindones.org/index.php/ijim/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.

Metadata asli (oai_dc)

<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Vitamin D Levels in Pre-frail Older Adults and Its Correlation with Hand Grip Strength</dc:title>
	<dc:creator>Dwimartutie, Noto</dc:creator>
	<dc:creator>Setiati, Siti</dc:creator>
	<dc:creator>Tamin, Tirza Z</dc:creator>
	<dc:creator>Prijanti, Ani Retno</dc:creator>
	<dc:creator>Harahap, Alida R</dc:creator>
	<dc:creator>Purnamasari, Dyah</dc:creator>
	<dc:creator>Harimurti, Kuntjoro</dc:creator>
	<dc:creator>Pramantara, I Dewa Putu</dc:creator>
	<dc:subject xml:lang="en-US">Hand grip strength</dc:subject>
	<dc:subject xml:lang="en-US">Older adults</dc:subject>
	<dc:subject xml:lang="en-US">Pre-frail</dc:subject>
	<dc:subject xml:lang="en-US">Vitamin D level</dc:subject>
	<dc:subject xml:lang="en-US">geriatric</dc:subject>
	<dc:description xml:lang="en-US">Background: Vitamin D deficiency is frequent in older adults and associated with poor musculoskeletal function. The prevalence of pre-frailty is also high in older persons, who may proceed to a frail state. This study aimed to determine the vitamin D levels in pre-frail older adults and its correlation with hand grip strength. Methods: A cross-sectional study was conducted on older adults (age &amp;gt; 60 years) with a pre-frail condition who were visiting the outpatient geriatric clinic at Cipto Mangunkusumo Hospital in Jakarta, Indonesia. Serum levels of vitamin D, measured as 25(OH)D, were determined by enzyme-linked immunosorbent assay (ELISA), and hand grip strength was measured using a Jamar hydraulic dynamometer. Correlations between vitamin D levels and hand grip strength were evaluated by Spearman’s rank correlation coefficient. Multiple linear regression analysis was carried out to assess contribution of variables that influence hand grip strength. Results: Of 95 pre-frail older adults (mean age 70.08 ± 5.35 years), 67.4% were female,  and the median vitamin D level was 17.91 (interquartile range/IQR 13.68–26.36) ng/mL. Overall, 11.6% of the participants had normal vitamin D levels, whereas 34.7% and 53.7% had insufficient and deficient levels, respectively. Females were more likely to have inadequacy of vitamin D than males.  Those with vitamin D deficiency tended to have a higher body mass index (BMI) and lower vitamin D intake than normal levels. A significant correlation between serum vitamin D levels and hand grip strength was observed (r = 0.283; P = 0.006). After adjusting for age, comorbidities, nutritional status, functional status, BMI, protein intake, and sun exposure score, regression analysis between hand grip strength and vitamin D levels gave standard coefficient beta = 0.255 (P = 0.013). Conclusion: In this study, pre-frail older adults had a high proportion of deficient and insufficient vitamin D levels, and a significant correlation was found between serum vitamin D levels and hand grip strength.</dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2023-07-28</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/2309</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 55 No. 2 (2023): Acta Medica Indonesiana; 172</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/2309/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 Noto Dwimartutie</dc:rights>
</oai_dc:dc>