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The Iodine Status of Women of Childbearing Age in an Iodine-repleted Area: An Epidemiological Study in Sengi Village on Merapi Mountain Area

ACTA MEDICA INDONESIANA · Vol. 55 No. 2 (2023)

ISSN
2338-2732, 0125-9326
Terbit
2023-07-28
Penerbit
The Indonesian Society of Internal Medicine
Bahasa
eng

Abstrak

Background: The low iodine content of daily water sources and repeated volcanic eruptions are expected to affect the iodine status and thyroid hormone profile of women of childbearing age in the Magelang regency. This study aimed to determine the iodine and thyroid profile among women of childbearing age. Methods: We used a cross-sectional descriptive study to learn about 140 women of reproductive age living in Sengi village from October 2017 to January 2018. We assessed the iodine level, dietary intake, and goitrogenic food consumption using food frequency questionnaire (FFQ), urinary iodine concentration (UIC), thyroid stimulating hormone (TSH) and free thyroxine (fT4), and total goiter rate (TGR). Results: The median UIC was 199.5 (126.0 – 264.0)µg/L. The TGR was 10.7% on palpation and 7.8% on ultrasound. The proportion of UIC levels below 100µg/L was 18.5%. The mean water iodine content was 2.03 ± 4.74 μg/L. The mean salt iodine level was 28.6±13.7ppm. There were only 35% who consumed salt with adequate iodine contents, and only 19.29% consumed >150µg iodine from daily dietary intake based on FFQ. The median TSH and FT4 levels were 1.72 and 1.51mIU/L. Conclusion: Women of childbearing age in Sengi Village generally had adequate iodine profiles and normal thyroid hormone levels but a considerable proportion of TGR and low UIC. The iodine contents within the freshwater source, table salt, and daily dietary intake were low. There are no significant association between Iodine status, daily goitrogen intake, daily iodine intake and salt iodine concentration

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Samsuridjal DjauziAfiliasi tidak diketahui2
Hery D PurnomoAfiliasi tidak diketahui1
Farmaditya EF MundhofirAfiliasi tidak diketahui1
Kasno KasnoSoutheast Asian Regional Centre for Tropical Biology1
Eddy SudijantoAfiliasi tidak diketahui1
Daldiyono HardjodisatroAfiliasi tidak diketahui1
R Djokomoeljanto1Afiliasi tidak diketahui1
Sultana MH FaradzAfiliasi tidak diketahui1
Joedo PrihartonoAfiliasi tidak diketahui1
Asmarinah AsmarinahAfiliasi tidak diketahui1
Alida HarahapAfiliasi tidak diketahui1
Fatimah ElianaAfiliasi tidak diketahui1
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Metadata asli (oai_dc)
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">The Iodine Status of Women of Childbearing Age  in an Iodine-repleted Area: An Epidemiological Study  in Sengi Village on Merapi Mountain Area</dc:title>
	<dc:creator>Nugroho, Heri</dc:creator>
	<dc:creator>Pemayun, Tjokorda Gde Dalem</dc:creator>
	<dc:creator>Darmono, Darmono</dc:creator>
	<dc:creator>Rachmawati, Banundari</dc:creator>
	<dc:subject xml:lang="en-US">Endocrinology</dc:subject>
	<dc:subject xml:lang="en-US">Thyroid</dc:subject>
	<dc:subject xml:lang="en-US">Goiter</dc:subject>
	<dc:subject xml:lang="en-US">Iodine status</dc:subject>
	<dc:subject xml:lang="en-US">Women of childbearing age</dc:subject>
	<dc:subject xml:lang="en-US">Thyroid</dc:subject>
	<dc:description xml:lang="en-US">Background: The low iodine content of daily water sources and repeated volcanic eruptions are expected to affect the iodine status and thyroid hormone profile of women of childbearing age in the Magelang regency. This study aimed to determine the iodine and thyroid profile among women of childbearing age. Methods: We used a cross-sectional descriptive study to learn about 140 women of reproductive age living in Sengi village from October 2017 to January 2018. We assessed the iodine level, dietary intake, and goitrogenic food consumption using food frequency questionnaire (FFQ), urinary iodine concentration (UIC), thyroid stimulating hormone (TSH) and free thyroxine (fT4), and total goiter rate (TGR). Results: The median UIC was 199.5 (126.0 – 264.0)µg/L. The TGR was 10.7% on palpation and 7.8% on ultrasound. The proportion of UIC levels below 100µg/L was 18.5%. The mean water iodine content was 2.03 ± 4.74 μg/L. The mean salt iodine level was 28.6±13.7ppm. There were only 35% who consumed salt with adequate iodine contents, and only 19.29% consumed &amp;gt;150µg iodine from daily dietary intake based on FFQ. The median TSH and FT4 levels were 1.72 and 1.51mIU/L. Conclusion: Women of childbearing age in Sengi Village generally had adequate iodine profiles and normal thyroid hormone levels but a considerable proportion of TGR and low UIC. The iodine contents within the freshwater source, table salt, and daily dietary intake were low. There are no significant association between Iodine status, daily goitrogen intake, daily iodine intake and salt iodine concentration</dc:description>
	<dc:publisher xml:lang="en-US">The Indonesian Society of Internal Medicine</dc:publisher>
	<dc:date>2023-07-28</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Cross-sectional</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://www.actamedindones.org/index.php/ijim/article/view/2397</dc:identifier>
	<dc:source xml:lang="en-US">Acta Medica Indonesiana; Vol. 55 No. 2 (2023): Acta Medica Indonesiana; 142</dc:source>
	<dc:source>2338-2732</dc:source>
	<dc:source>0125-9326</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://www.actamedindones.org/index.php/ijim/article/view/2397/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 Heri Nugroho, Tjokorda Gde Dalem Pemayun, Darmono Darmono, Banundari Rachmawati</dc:rights>
</oai_dc:dc>