Melola Discovery

← Melola Discovery

Jurnal SINTA 1

Effects of Anadara granosa shell combined with Sardinella longiceps oil on oesteoblast proliferation in bone defect healing process

Dental Journal (Majalah Kedokteran Gigi) · Vol. 49 No. 1 (2016) · hlm. 27–31

DOI
10.20473/j.djmkg.v49.i1.p27-31
ISSN
2442-9740, 1978-3728
Terbit
2016-03-31
Penerbit
Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
Bahasa
eng

Abstrak

Background: Alveolar bone damage is the most common case in dentistry. One way to fix the bone damage is by using bone graft. Anadara granosa shell is a potential bone substitute since it is rich in calcium which can be processed into hydroxyapatite. The addition of Sardinella longiceps oil rich in omega-3 can modulate inflammation, thus accelerating the healing process. Purpose: This study aimed to determine effects of application of Anadara granosa shell combined with Sardinella longiceps oil on osteoblast proliferation in the healing process of bone defects. Method: The subjects were 32 male rats type Wistar divided into 4 groups (n = 8). Making defect was performed on the right bone of the femurs with a half of the diameter of round Mcisinger® Germany bur sized 18. The first group (K) is a negative control group that was not given anything. The second group (AG) was given Anadara granosa pasta. The third group (AM10) was given Anadara granosa pasta combined with 10% Sardinella longiceps oil. And, the fourth group (AM30) was given Anadara granosa pasta combined with 30% Sardinella longiceps oil. Next, preparations and animal euthanasia were performed on the 7th day after the treatment. The number of osteoblasts then was measured after making preparations for HPA with Hematoxylin eosin staining (HE). Afterward, tabulation of data followed by statistical analysis of Anova and HSD Tukey was carried out. Result: The average number of osteoblasts in Groups K, AG, AM10, and AM30 was 19.00, 34.63, 33.50, and 38.50. The results of Anova test showed a significant difference (p<0.05). Similarly, the results of Tukey-HSD test also showed significant differences (p<0.05) between Group K and all other groups (AG, AM10, and AM30). Nevertheless, there were no significant differences between Group AG and Groups AM10 and AM30, as well as between Group AM10 and Group AM30. Conclusion: The application of the combination of Anadara granosa shell and Sardinella longiceps oil can not increase the proliferation of osteoblasts in the healing process of bone defects.

Kata kunci

Jaringan kolaborasi para penulis

29 penulis · 135 tautan kepenulisan bersama · 10 lintas organisasi

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

  • Universitas Hang Tuah
  • Universitas Airlangga
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
  • Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Widyasri PrananingrumUniversitas Hang Tuah3
Syamsulina ReviantiUniversitas Hang Tuah2
Hansen KurniawanUniversitas Hang Tuah2
Asri Cahyadita Dwi ImaniarUniversitas Hang Tuah2
Kevin AnggoroUniversitas Hang Tuah2
Arya BrahmantaUniversitas Hang Tuah2
Maharani Dewinta SariUniversitas Hang Tuah2
Andiani RamanindiaUniversitas Hang Tuah2
Karimatul FitriUniversitas Hang Tuah2
Michelle Rosalind SusantoUniversitas Hang Tuah2
Safira Agnes PratiwiUniversitas Hang Tuah2
Diajeng Ayu Permatasari YusufUniversitas Hang Tuah2
Vivin AriestaniaUniversitas Hang Tuah2
WidaningsihUniversitas Hang Tuah2
Anindita ApsariUniversitas Hang Tuah2
WidyastutiUniversitas Hang Tuah2
Endah WahjuningsihUniversitas Hang Tuah1
Isidora Karsini SUniversitas Hang Tuah1
Yenny SugihartoUniversitas Hang Tuah1
Retno Pudji RahayuUniversitas Airlangga1
Sri Agus SudjarwoUniversitas Airlangga1
Aisah Faiz BachmidUniversitas Hang Tuah1
Dian MulawarmantiUniversitas Hang Tuah1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/MKG/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Effects of Anadara granosa shell combined with Sardinella longiceps oil on oesteoblast proliferation in bone defect healing process</dc:title>
	<dc:creator>Sari, Rima Parwati</dc:creator>
	<dc:creator>Hermanto, Eddy</dc:creator>
	<dc:creator>Divilia, Dinda</dc:creator>
	<dc:creator>Candra, Indra</dc:creator>
	<dc:creator>Kuncoro, Wisnu</dc:creator>
	<dc:creator>Liswanti, Tantri</dc:creator>
	<dc:subject xml:lang="en-US">Anadara granosa</dc:subject>
	<dc:subject xml:lang="en-US">sardinella longiceps oil</dc:subject>
	<dc:subject xml:lang="en-US">bone graft</dc:subject>
	<dc:subject xml:lang="en-US">osteoblasts</dc:subject>
	<dc:subject xml:lang="en-US">bone healing</dc:subject>
	<dc:description xml:lang="en-US">Background: Alveolar bone damage is the most common case in dentistry. One way to fix the bone damage is by using bone graft. Anadara granosa shell is a potential bone substitute since it is rich in calcium which can be processed into hydroxyapatite. The addition of Sardinella longiceps oil rich in omega-3 can modulate inflammation, thus accelerating the healing process. Purpose: This study aimed to determine effects of application of Anadara granosa shell combined with Sardinella longiceps oil on osteoblast proliferation in the healing process of bone defects. Method: The subjects were 32 male rats type Wistar divided into 4 groups (n = 8). Making defect was performed on the right bone of the femurs with a half of the diameter of round Mcisinger® Germany bur sized 18. The first group (K) is a negative control group that was not given anything. The second group (AG) was given Anadara granosa pasta. The third group (AM10) was given Anadara granosa pasta combined with 10% Sardinella longiceps oil. And, the fourth group (AM30) was given Anadara granosa pasta combined with 30% Sardinella longiceps oil. Next, preparations and animal euthanasia were performed on the 7th day after the treatment. The number of osteoblasts then was measured after making preparations for HPA with Hematoxylin eosin staining (HE). Afterward, tabulation of data followed by statistical analysis of Anova and HSD Tukey was carried out. Result: The average number of osteoblasts in Groups K, AG, AM10, and AM30 was 19.00, 34.63, 33.50, and 38.50. The results of Anova test showed a significant difference (p&amp;lt;0.05). Similarly, the results of Tukey-HSD test also showed significant differences (p&amp;lt;0.05) between Group K and all other groups (AG, AM10, and AM30). Nevertheless, there were no significant differences between Group AG and Groups AM10 and AM30, as well as between Group AM10 and Group AM30. Conclusion: The application of the combination of Anadara granosa shell and Sardinella longiceps oil can not increase the proliferation of osteoblasts in the healing process of bone defects.</dc:description>
	<dc:publisher xml:lang="en-US">Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en</dc:publisher>
	<dc:date>2016-03-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/MKG/article/view/2771</dc:identifier>
	<dc:identifier>10.20473/j.djmkg.v49.i1.p27-31</dc:identifier>
	<dc:source xml:lang="en-US">Dental Journal (Majalah Kedokteran Gigi); Vol. 49 No. 1 (2016): March 2016; 27-31</dc:source>
	<dc:source>2442-9740</dc:source>
	<dc:source>1978-3728</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/MKG/article/view/2771/2194</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2016 Dental Journal (Majalah Kedokteran Gigi)</dc:rights>
</oai_dc:dc>