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The correlation between the use of personal protective equipment and level wild-type p53 of dental technicians in Surabaya

Dental Journal (Majalah Kedokteran Gigi) · Vol. 50 No. 1 (2017) · hlm. 19–22

DOI
10.20473/j.djmkg.v50.i1.p19-22
ISSN
2442-9740, 1978-3728
Terbit
2017-03-31
Penerbit
Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
Bahasa
eng

Abstrak

Background: Exposure of metals among dental technicians that come from the working environment can lead to the formation reactive oxygen species (ROS). ROS can cause mutations in the p53 gene (p53). The mutation is transversion mutation GuanineThymine. p53 mutations can lead to low expression of the wild-type p53 protein (p53). Wild-type p53 involved in many biological processes such as regulation of genes involved in cell cycle, cell growth after DNA damage, and apoptosis. However, exposure to metals among dental technicians can be prevented through the use of personal protective equipment (PPE) during work. Purpose: The purpose of this study was to analyze the correlation between the use of personal protective equipment to wild-type p53 protein levels among dental technicians in Surabaya. Method: This study was observational analytic with cross sectional approach. 40 samples were taken by random sampling. Data were retrieved through interviews and observations. Wild-type p53 was analyzed from saliva with indirect ELISA method. Analysis of data used Kolmogorov Smirnov normality test and a Pearson correlation test. Value significance was p<0.05 (95% confidence level). Result: There was a significant association between the use of personal protective equipment with wild-type p53 levels with p=0.002 Conclusion: The use PPE properly is positively correlated with the wild-type p53 protein levels of dental technicians in Surabaya.

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  • Universitas Airlangga
  • Universitas Hang Tuah
  • Institut Ilmu Kesehatan Bhakti Wiyata
  • Universitas Jember
  • Lambung Mangkurat University
  • Institut Teknologi Sepuluh Nopember
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Rekan penulisOrganisasiArtikel bersama
Utari KresnoadiUniversitas Airlangga3
Diah Savitri ErnawatiUniversitas Airlangga3
Maharani Laillyza ApriasariLambung Mangkurat University2
Ira ArundinaUniversitas Airlangga2
Meircurius Dwi Condro SurboyoUniversitas Airlangga2
Kharinna WidowatiUniversitas Hang Tuah2
Ardyni Febri KUniversitas Airlangga1
Agung SosiawanUniversitas Airlangga1
Sri HernawatiUniversitas Jember1
Fedik Abdul RantamUniversitas Airlangga1
I Ketut SudianaUniversitas Airlangga1
Ninuk HariyaniUniversitas Airlangga1
Kromodiharjo SudiyonoInstitut Teknologi Sepuluh Nopember1
Retno IndrawatiUniversitas Airlangga1
Regina Purnama Dewi IskandarUniversitas Airlangga1
Fitria RahmitasariUniversitas Hang Tuah1
Elly MunadzirohUniversitas Airlangga1
Wahyu Aji WibowoUniversitas Airlangga1
Retno Indrawati RoestamadjiUniversitas Airlangga1
Jenny SunarianiUniversitas Airlangga1
Hari WibowoUniversitas Airlangga1
Indeswati DiyatriUniversitas Airlangga1
Fiory Dioptis PutriwijayaInstitut Ilmu Kesehatan Bhakti Wiyata1
Maretaningtias Dwi ArianiUniversitas Airlangga1
Saka WiniasUniversitas Airlangga1
Rima Parwati SariUniversitas Hang Tuah1
Syamsulina ReviantiUniversitas Hang Tuah1
Widyasri PrananingrumUniversitas Hang Tuah1
Sri Agus SudjarwoUniversitas Airlangga1
Hansen KurniawanUniversitas Hang Tuah1
Aisah Faiz BachmidUniversitas Hang Tuah1
Imam Safari AzharUniversitas Airlangga1
Christian KhoswantoUniversitas Airlangga1
Muhammad LuthfiUniversitas Airlangga1
Aqsa Sjuhada OkiUniversitas Airlangga1
Moch. Febi AlviansyahUniversitas Airlangga1
Yani Corvianindya RahayuUniversitas Jember1

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Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/MKG/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en-US">The correlation between the use of personal protective equipment and level wild-type p53 of dental technicians in Surabaya</dc:title>
	<dc:creator>Rohmaniar, Puspa Dila</dc:creator>
	<dc:creator>Berniyanti, Titiek</dc:creator>
	<dc:creator>Rahayu, Retno Pudji</dc:creator>
	<dc:subject xml:lang="en-US">personal protective equipment</dc:subject>
	<dc:subject xml:lang="en-US">dental technician</dc:subject>
	<dc:subject xml:lang="en-US">P53 wild</dc:subject>
	<dc:description xml:lang="en-US">Background: Exposure of metals among dental technicians that come from the working environment can lead to the formation reactive oxygen species (ROS). ROS can cause mutations in the p53 gene (p53). The mutation is transversion mutation GuanineThymine. p53 mutations can lead to low expression of the wild-type p53 protein (p53). Wild-type p53 involved in many biological processes such as regulation of genes involved in cell cycle, cell growth after DNA damage, and apoptosis. However, exposure to metals among dental technicians can be prevented through the use of personal protective equipment (PPE) during work. Purpose: The purpose of this study was to analyze the correlation between the use of personal protective equipment to wild-type p53 protein levels among dental technicians in Surabaya. Method: This study was observational analytic with cross sectional approach. 40 samples were taken by random sampling. Data were retrieved through interviews and observations. Wild-type p53 was analyzed from saliva with indirect ELISA method. Analysis of data used Kolmogorov Smirnov normality test and a Pearson correlation test. Value significance was p&amp;lt;0.05 (95% confidence level). Result: There was a significant association between the use of personal protective equipment with wild-type p53 levels with p=0.002 Conclusion: The use PPE properly is positively correlated with the wild-type p53 protein levels of dental technicians in Surabaya.</dc:description>
	<dc:publisher xml:lang="en-US">Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en</dc:publisher>
	<dc:date>2017-03-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/MKG/article/view/4073</dc:identifier>
	<dc:identifier>10.20473/j.djmkg.v50.i1.p19-22</dc:identifier>
	<dc:source xml:lang="en-US">Dental Journal (Majalah Kedokteran Gigi); Vol. 50 No. 1 (2017): March 2017; 19-22</dc:source>
	<dc:source>2442-9740</dc:source>
	<dc:source>1978-3728</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/MKG/article/view/4073/3016</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2017 Dental Journal (Majalah Kedokteran Gigi)</dc:rights>
</oai_dc:dc>