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The effect of various concentrations of HA-TCP derived from cockle shell synthesis on scaffold porosity

Dental Journal (Majalah Kedokteran Gigi) · Vol. 51 No. 3 (2018) · hlm. 114–118

DOI
10.20473/j.djmkg.v51.i3.p114-118
ISSN
2442-9740, 1978-3728
Terbit
2018-09-30
Penerbit
Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
Bahasa
eng

Abstrak

Background: Porosity is an important property that must be possessed by scaffold due to its role in new bone growth. Hydroxyapatite is a scaffold material with a composition resembling that of bone that can be synthesized from cockle shell (Anadara granosa). Purpose: This research aimed to determine the effects of various HA-TCP concentrations (wt%) derived from cockle shell synthesis on scaffold porosity. Methods: HA-TCP was synthesized from cockle shells using a hydrothermal method at 200o C with a 12-hour sintering process period. An XRD test was subsequently carried out to determine the composition of hydroxyapatite (HA) and tricalcium phosphate (TCP) compounds. Eighteen scaffold samples (n=6) were then produced using a freeze dry method and divided into three groups, namely; Group 1 (K1) treated with 5% HA-TCP, Group 2 (K2) treated with 25% HA-TCP and Group 3 (K3) treated with 50% HA-TCP. Thereafter, a scaffold porosity test was conducted using liquid displacement method. Scaffold porosity was observed by means of an SEM image. A One-Way ANOVA test was subsequently performed, followed by an LSD Post-Hoc test (p <0.05). Results: The results of the XRD test showed that the percentage of HA was 51.5%, while TCP was 16.8%. The porosity of the scaffolds was within the range of 67.24% - 80.17%. The highest porosity was found in Group 1, while the lowest occurred in Group 3. There were significant differences in all groups. Conclusion: The concentration of HA-TCP derived from the synthesis of cockle shells affects the porosity of scaffold. The lower the concentration of HA-TCP, the higher the scaffold porosity.

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  • Universitas Hang Tuah
  • Universitas Airlangga
  • Universitas Negeri Surabaya
  • Institut Teknologi Sepuluh Nopember
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Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Rima Parwati SariUniversitas Hang Tuah2
Fitria RahmitasariUniversitas Hang Tuah2
Grace Caroline SetiawanUniversitas Hang Tuah2
Puguh Bayu PrabowoUniversitas Hang Tuah1
Retno Pudji RahayuUniversitas Airlangga1
Syamsulina ReviantiUniversitas Hang Tuah1
Sri Agus SudjarwoUniversitas Airlangga1
Hansen KurniawanUniversitas Hang Tuah1
Aisah Faiz BachmidUniversitas Hang Tuah1
Desak Putu Sudarmi AriUniversitas Hang Tuah1
Firda Dean YonatasyaUniversitas Hang Tuah1
Gita SaftiariniUniversitas Hang Tuah1
Adelia TinisiaUniversitas Hang Tuah1
Muhammad Galang Adhinata Abdul RahimUniversitas Hang Tuah1
Sularsih SularsihUniversitas Hang Tuah1
Sri FatmawatiInstitut Teknologi Sepuluh Nopember1
Vindya Meinda PutriUniversitas Hang Tuah1
Baiq Nadia Risna WahyuningUniversitas Hang Tuah1
Nurina Rizka RamadhaniaUniversitas Negeri Surabaya1
Arya BrahmantaUniversitas Hang Tuah1
Eddy HermantoUniversitas Hang Tuah1
Maharani Dewinta SariUniversitas Hang Tuah1
Andiani RamanindiaUniversitas Hang Tuah1
Karimatul FitriUniversitas Hang Tuah1
Michelle Rosalind SusantoUniversitas Hang Tuah1
Safira Agnes PratiwiUniversitas Hang Tuah1
Diajeng Ayu Permatasari YusufUniversitas Hang Tuah1
Vivin AriestaniaUniversitas Hang Tuah1
WidaningsihUniversitas Hang Tuah1
Anindita ApsariUniversitas Hang Tuah1
WidyastutiUniversitas Hang Tuah1

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Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/MKG/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en-US">The effect of various concentrations of HA-TCP derived from cockle shell synthesis on scaffold porosity</dc:title>
	<dc:creator>Ferdynanto, Reyhan Alvaryan</dc:creator>
	<dc:creator>Dharmayanti, Priska Evita Setia</dc:creator>
	<dc:creator>Dewi, Putu Tahlia Krisna</dc:creator>
	<dc:creator>Prananingrum, Widyasri</dc:creator>
	<dc:subject xml:lang="en-US">HA-TCP concentration</dc:subject>
	<dc:subject xml:lang="en-US">gelatin</dc:subject>
	<dc:subject xml:lang="en-US">porosity</dc:subject>
	<dc:subject xml:lang="en-US">scaffold</dc:subject>
	<dc:subject xml:lang="en-US">cockle shells</dc:subject>
	<dc:description xml:lang="en-US">Background: Porosity is an important property that must be possessed by scaffold due to its role in new bone growth. Hydroxyapatite is a scaffold material with a composition resembling that of bone that can be synthesized from cockle shell (Anadara granosa). Purpose: This research aimed to determine the effects of various HA-TCP concentrations (wt%) derived from cockle shell synthesis on scaffold porosity. Methods: HA-TCP was synthesized from cockle shells using a hydrothermal method at 200o C with a 12-hour sintering process period. An XRD test was subsequently carried out to determine the composition of hydroxyapatite (HA) and tricalcium phosphate (TCP) compounds. Eighteen scaffold samples (n=6) were then produced using a freeze dry method and divided into three groups, namely; Group 1 (K1) treated with 5% HA-TCP, Group 2 (K2) treated with 25% HA-TCP and Group 3 (K3) treated with 50% HA-TCP. Thereafter, a scaffold porosity test was conducted using liquid displacement method. Scaffold porosity was observed by means of an SEM image. A One-Way ANOVA test was subsequently performed, followed by an LSD Post-Hoc test (p &amp;lt;0.05). Results: The results of the XRD test showed that the percentage of HA was 51.5%, while TCP was 16.8%. The porosity of the scaffolds was within the range of 67.24% - 80.17%. The highest porosity was found in Group 1, while the lowest occurred in Group 3. There were significant differences in all groups. Conclusion: The concentration of HA-TCP derived from the synthesis of cockle shells affects the porosity of scaffold. The lower the concentration of HA-TCP, the higher the scaffold porosity.</dc:description>
	<dc:publisher xml:lang="en-US">Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en</dc:publisher>
	<dc:date>2018-09-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/MKG/article/view/10391</dc:identifier>
	<dc:identifier>10.20473/j.djmkg.v51.i3.p114-118</dc:identifier>
	<dc:source xml:lang="en-US">Dental Journal (Majalah Kedokteran Gigi); Vol. 51 No. 3 (2018): September 2018; 114-118</dc:source>
	<dc:source>2442-9740</dc:source>
	<dc:source>1978-3728</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/MKG/article/view/10391/6265</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2018 Dental Journal (Majalah Kedokteran Gigi)</dc:rights>
</oai_dc:dc>