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Variations of gelatin percentages in HA-TCP scaffolds as the result of 6- and 12-hour sintering processes of blood cockle (Anadara granosa) shells against porosity

Dental Journal (Majalah Kedokteran Gigi) · Vol. 51 No. 4 (2018) · hlm. 158–163

DOI
10.20473/j.djmkg.v51.i4.p158-163
ISSN
2442-9740, 1978-3728
Terbit
2018-12-31
Penerbit
Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
Bahasa
eng

Abstrak

Background: Porous scaffold is one type of biomaterial primarily employed as a bone substitute material which demonstrates superior osteoconductive and osteointegrative properties than solid scaffold since it can stimulate and accelerate the growth of new tissue. For the purposes of this study, porous scaffold was produced using hydroxyapatite-tricalcium phosphate (HA-TCP) powder derived from a synthesis of blood cockle (Anadara granosa) shells and gelatin. Purpose: The aim of this study was to reveal the effects of the percentage of gelatin in HA-TCP scaffolds derived from 6- and 12-hours sintering processes involving blood cockle shells on porosity. Methods: HA-TCP powder was derived from a synthesis of Anadara granosa shells using a hydrothermal method at 200oC with sintering periods of 6 and 12 hours. A XRD test was subsequently conducted to reveal the compositions of HA-TCP powder. The 24 scaffold samples (n=6) employed were manufactured using a freeze dry method before being divided into four groups, namely; Group 1 using 25% HA-TCP powder (a six-hour sintering process) combined with 20% gelatin, Group 2 using 25% HA-TCP powder (a six-hour sintering process) combined with 10% gelatin, Group 3 using 25% HA-TCP powder (a twelve-hour sintering process) combined with 20% gelatin; and Group 4 using 25% HA-TCP powder (a twelve-hour sintering process) combined with 10% gelatin. A scaffold porosity test was subsequently carried out using a liquid displacement method. A one-way ANOVA test was performed using SPSS, followed by a Post-Hoc LSD (p<0.05). Results: The statistical results for scaffold porosity were within the range of 67.21 -77.51%. The highest porosity was found in Group 3, while the lowest was in Group 4. Significant differences were also present in all groups. Conclusion: Variations in the percentage of gelatin can affect the porosity of HA-TCP scaffolds derived from 6-and 12 hours sintrering processes blood cockle shells. The smaller the percentage of gelatin, the higher the porosity.

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  • Universitas Hang Tuah
  • Universitas Airlangga
  • Universitas Negeri Surabaya
  • Institut Teknologi Sepuluh Nopember
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Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Rima Parwati SariUniversitas Hang Tuah2
Fitria RahmitasariUniversitas Hang Tuah2
Grace Caroline SetiawanUniversitas Hang Tuah2
Puguh Bayu PrabowoUniversitas Hang Tuah1
Retno Pudji RahayuUniversitas Airlangga1
Syamsulina ReviantiUniversitas Hang Tuah1
Sri Agus SudjarwoUniversitas Airlangga1
Hansen KurniawanUniversitas Hang Tuah1
Aisah Faiz BachmidUniversitas Hang Tuah1
Reyhan Alvaryan FerdynantoUniversitas Hang Tuah1
Priska Evita Setia DharmayantiUniversitas Hang Tuah1
Putu Tahlia Krisna DewiUniversitas Hang Tuah1
Adelia TinisiaUniversitas Hang Tuah1
Muhammad Galang Adhinata Abdul RahimUniversitas Hang Tuah1
Sularsih SularsihUniversitas Hang Tuah1
Sri FatmawatiInstitut Teknologi Sepuluh Nopember1
Vindya Meinda PutriUniversitas Hang Tuah1
Baiq Nadia Risna WahyuningUniversitas Hang Tuah1
Nurina Rizka RamadhaniaUniversitas Negeri Surabaya1
Arya BrahmantaUniversitas Hang Tuah1
Eddy HermantoUniversitas Hang Tuah1
Maharani Dewinta SariUniversitas Hang Tuah1
Andiani RamanindiaUniversitas Hang Tuah1
Karimatul FitriUniversitas Hang Tuah1
Michelle Rosalind SusantoUniversitas Hang Tuah1
Safira Agnes PratiwiUniversitas Hang Tuah1
Diajeng Ayu Permatasari YusufUniversitas Hang Tuah1
Vivin AriestaniaUniversitas Hang Tuah1
WidaningsihUniversitas Hang Tuah1
Anindita ApsariUniversitas Hang Tuah1
WidyastutiUniversitas Hang Tuah1

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Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/MKG/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Variations of gelatin percentages in HA-TCP scaffolds as the result of 6- and 12-hour sintering processes of blood cockle (Anadara granosa) shells against porosity</dc:title>
	<dc:creator>Ari, Desak Putu Sudarmi</dc:creator>
	<dc:creator>Yonatasya, Firda Dean</dc:creator>
	<dc:creator>Saftiarini, Gita</dc:creator>
	<dc:creator>Prananingrum, Widyasri</dc:creator>
	<dc:subject xml:lang="en-US">Anadara granosa shell</dc:subject>
	<dc:subject xml:lang="en-US">HA-TCP</dc:subject>
	<dc:subject xml:lang="en-US">percentage of gelatin</dc:subject>
	<dc:subject xml:lang="en-US">porosity</dc:subject>
	<dc:subject xml:lang="en-US">scaffold</dc:subject>
	<dc:description xml:lang="en-US">Background: Porous scaffold is one type of biomaterial primarily employed as a bone substitute material which demonstrates superior osteoconductive and osteointegrative properties than solid scaffold since it can stimulate and accelerate the growth of new tissue. For the purposes of this study, porous scaffold was produced using hydroxyapatite-tricalcium phosphate (HA-TCP) powder derived from a synthesis of blood cockle (Anadara granosa) shells and gelatin. Purpose: The aim of this study was to reveal the effects of the percentage of gelatin in HA-TCP scaffolds derived from 6- and 12-hours sintering processes involving blood cockle shells on porosity. Methods: HA-TCP powder was derived from a synthesis of Anadara granosa shells using a hydrothermal method at 200oC with sintering periods of 6 and 12 hours. A XRD test was subsequently conducted to reveal the compositions of HA-TCP powder. The 24 scaffold samples (n=6) employed were manufactured using a freeze dry method before being divided into four groups, namely; Group 1 using 25% HA-TCP powder (a six-hour sintering process) combined with 20% gelatin, Group 2 using 25% HA-TCP powder (a six-hour sintering process) combined with 10% gelatin, Group 3 using 25% HA-TCP powder (a twelve-hour sintering process) combined with 20% gelatin; and Group 4 using 25% HA-TCP powder (a twelve-hour sintering process) combined with 10% gelatin. A scaffold porosity test was subsequently carried out using a liquid displacement method. A one-way ANOVA test was performed using SPSS, followed by a Post-Hoc LSD (p&amp;lt;0.05). Results: The statistical results for scaffold porosity were within the range of 67.21 -77.51%. The highest porosity was found in Group 3, while the lowest was in Group 4. Significant differences were also present in all groups. Conclusion: Variations in the percentage of gelatin can affect the porosity of HA-TCP scaffolds derived from 6-and 12 hours sintrering processes blood cockle shells. The smaller the percentage of gelatin, the higher the porosity.</dc:description>
	<dc:publisher xml:lang="en-US">Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en</dc:publisher>
	<dc:date>2018-12-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/MKG/article/view/10394</dc:identifier>
	<dc:identifier>10.20473/j.djmkg.v51.i4.p158-163</dc:identifier>
	<dc:source xml:lang="en-US">Dental Journal (Majalah Kedokteran Gigi); Vol. 51 No. 4 (2018): December 2018; 158-163</dc:source>
	<dc:source>2442-9740</dc:source>
	<dc:source>1978-3728</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/MKG/article/view/10394/7174</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2018 Dental Journal (Majalah Kedokteran Gigi)</dc:rights>
</oai_dc:dc>