Melola Discovery

← Melola Discovery

Jurnal SINTA 1

Effective dose of propolis extract combined with bovine bone graft on the number of osteoblasts and osteoclasts in tooth extraction socket preservation

Dental Journal (Majalah Kedokteran Gigi) · Vol. 53 No. 1 (2020) · hlm. 40–44

DOI
10.20473/j.djmkg.v53.i1.p40-44
ISSN
2442-9740, 1978-3728
Terbit
2020-03-31
Penerbit
Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
Bahasa
eng

Abstrak

Background: Maintaining a good ridge is required during prosthodontic treatment. Hence, adequate alveolar bone support is considered an important factor in pursuing successful dentures. Propolis extract combined with bovine bone graft is a recent and innovative material in the process of socket preservation, as the caffeic acid phenethyl ester (CAPE) it contains can suppress the inflammatory process. Purpose: This study aims to determine the effective dose of propolis extract combined with bovine bone graft on the number of osteoblasts and osteoclasts in socket preservation. Methods: Twenty-eight Cavia cobaya animals were divided into four groups of seven. Group I was given 25 grams of PEG, while Group II were given a propolis extract at a dose of 0.5% combined with bovine bone graft. Group III were given a propolis extract at a dose of 1% combined with bovine bone graft and Group IV were given a propolis extract at a dose of 2% combined with bovine bone graft. On day 30, the lower incisor of each subject was extracted and induced with PEG and propolis (dose 0.5%, 1%, 2%). Histopathological examinations of osteoblasts and osteoclasts were measured with a 400x magnification light microscope. One-way ANOVA and Tukey HSD tests were performed to analyse data statistically. Results: The propolis extract combined with bovine bone graft not only increased the number of osteoblasts but also reduced the number of osteoclasts. The most effective dose for the propolis extract combined with bovine bone graft was 2%. Conclusion: The propolis extract combined with bovine bone graft could be effective in tooth extraction socket preservation at a dose of 2%.

Kata kunci

Jaringan kolaborasi para penulis

32 penulis · 75 tautan kepenulisan bersama · 20 lintas organisasi

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

  • Universitas Airlangga
  • Bhatia Hospital
  • Universitas Jember
  • Bandung Institute of Technology
  • Tohoku University
  • Universitas Ciputra
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
  • Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Retno Pudji RahayuUniversitas Airlangga3
Imam Safari AzharUniversitas Airlangga2
S. SoekobagionoUniversitas Airlangga2
Eha DjulaehaUniversitas Airlangga1
Arif RachmanAfiliasi tidak diketahui1
Rostiny RostinyUniversitas Airlangga1
Waloejo NoegrohoBhatia Hospital1
Adi SubiantoUniversitas Airlangga1
Yurike HadisoesantoUniversitas Airlangga1
Harly PrabowoUniversitas Airlangga1
Sherman SalimUniversitas Airlangga1
Karina MundiratriUniversitas Airlangga1
Faurier Dzar Eljabbar LatiefBandung Institute of Technology1
I Ketut SudianaUniversitas Airlangga1
Amiyatun NainiUniversitas Jember1
Mohammad RubiantoUniversitas Airlangga1
Louisa Christy LunardhiUniversitas Airlangga1
Bambang AgustonoUniversitas Airlangga1
Much NizarUniversitas Airlangga1
Birgitta Dwitya Swastyayana SubiaktoUniversitas Airlangga1
Najla SalsabilaUniversitas Airlangga1
Primanda Nur RahmaniaUniversitas Airlangga1
Phara Aster Chandra AdventiaUniversitas Airlangga1
Bima Subiakto RahmaniUniversitas Airlangga1
Nobuhiro YodaTohoku University1
Ratri Maya SitalaksmiUniversitas Airlangga1
Cindy Ramadhan PutriUniversitas Airlangga1
Aishley YutassaUniversitas Airlangga1
Jennifer WidjajaUniversitas Ciputra1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/MKG/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Effective dose of propolis extract combined with bovine bone graft on the number of osteoblasts and osteoclasts in tooth extraction socket preservation</dc:title>
	<dc:creator>Prabowo, Teguh Setio Yuli</dc:creator>
	<dc:creator>Kresnoadi, Utari</dc:creator>
	<dc:creator>Hidayati, Hanoem Eka</dc:creator>
	<dc:subject xml:lang="en-US">bovine bone graft</dc:subject>
	<dc:subject xml:lang="en-US">effective dose</dc:subject>
	<dc:subject xml:lang="en-US">osteoblasts</dc:subject>
	<dc:subject xml:lang="en-US">osteoclasts</dc:subject>
	<dc:subject xml:lang="en-US">Propolis extract</dc:subject>
	<dc:description xml:lang="en-US">Background: Maintaining a good ridge is required during prosthodontic treatment. Hence, adequate alveolar bone support is considered an important factor in pursuing successful dentures. Propolis extract combined with bovine bone graft is a recent and innovative material in the process of socket preservation, as the caffeic acid phenethyl ester (CAPE) it contains can suppress the inflammatory process. Purpose: This study aims to determine the effective dose of propolis extract combined with bovine bone graft on the number of osteoblasts and osteoclasts in socket preservation. Methods: Twenty-eight Cavia cobaya animals were divided into four groups of seven. Group I was given 25 grams of PEG, while Group II were given a propolis extract at a dose of 0.5% combined with bovine bone graft. Group III were given a propolis extract at a dose of 1% combined with bovine bone graft and Group IV were given a propolis extract at a dose of 2% combined with bovine bone graft. On day 30, the lower incisor of each subject was extracted and induced with PEG and propolis (dose 0.5%, 1%, 2%). Histopathological examinations of osteoblasts and osteoclasts were measured with a 400x magnification light microscope. One-way ANOVA and Tukey HSD tests were performed to analyse data statistically. Results: The propolis extract combined with bovine bone graft not only increased the number of osteoblasts but also reduced the number of osteoclasts. The most effective dose for the propolis extract combined with bovine bone graft was 2%. Conclusion: The propolis extract combined with bovine bone graft could be effective in tooth extraction socket preservation at a dose of 2%. </dc:description>
	<dc:publisher xml:lang="en-US">Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en</dc:publisher>
	<dc:date>2020-03-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/MKG/article/view/17747</dc:identifier>
	<dc:identifier>10.20473/j.djmkg.v53.i1.p40-44</dc:identifier>
	<dc:source xml:lang="en-US">Dental Journal (Majalah Kedokteran Gigi); Vol. 53 No. 1 (2020): March 2020; 40-44</dc:source>
	<dc:source>2442-9740</dc:source>
	<dc:source>1978-3728</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/MKG/article/view/17747/10258</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2020 Dental Journal (Majalah Kedokteran Gigi)</dc:rights>
</oai_dc:dc>