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Post-tooth extraction induction effect of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft treatment on alveolar bone trabecula area

Dental Journal (Majalah Kedokteran Gigi) · Vol. 56 No. 2 (2023) · hlm. 127–131

DOI
10.20473/j.djmkg.v56.i2.p127-131
ISSN
2442-9740, 1978-3728
Terbit
2023-03-15
Penerbit
Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-sa/4.0

Abstrak

Background: After tooth extraction, alveolar bone resorption occurs naturally, followed by alveolar bone remodeling. Alveolar bone formation is characterized by an increase in density and expansion of the trabecular bone. Socket preservation using a combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) is expected to increase the area of the alveolar bone trabeculae and thus accelerate the process of alveolar bone formation. Purpose: This study aimed to determine if a combination of Moringa oleifera leaf extract and DFDBBX could increase the area of the alveolar bone trabeculae in tooth extraction sockets. Methods: With their lower left incisors extracted, the 56 Cavia cobayas were divided into eight treatment groups according to the material given: polyethylene glycol (PEG), DFDBBX and PEG, Moringa oleifera leaf extract and PEG, and a combination of Moringa oleifera leaf extract, DFDBBX, and PEG. On the seventh and thirtieth days, the Cavia cobayas were sacrificed and examined. Histopathological samples were stained with Hematoxylin-Eosin (HE) to evaluate the trabecula area, and data were analyzed using one-way ANOVA and Tukey HSD. Results: On the thirtieth day, the group that received a combination of Moringa oleifera leaf extract and DFDBBX had the greatest area of alveolar bone trabeculae. Conclusion: A combination of Moringa oleifera leaf extract and DFDBBX induced in the tooth extraction socket can increase the area of the alveolar bone trabeculae.

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Imam Safari AzharAfiliasi tidak diketahui2
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JajatAfiliasi tidak diketahui1
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Waloejo NoegrohoAfiliasi tidak diketahui1
Adi SubiantoAfiliasi tidak diketahui1
Yurike HadisoesantoAfiliasi tidak diketahui1
Harly PrabowoAfiliasi tidak diketahui1
I Ketut SudianaUniversitas Pendidikan Ganesha1
Amiyatun NainiAfiliasi tidak diketahui1
Mohammad RubiantoAfiliasi tidak diketahui1
Faurier Dzar Eljabbar LatiefAfiliasi tidak diketahui1
Louisa Christy LunardhiAfiliasi tidak diketahui1
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Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/MKG/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Post-tooth extraction induction effect of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft treatment on alveolar bone trabecula area</dc:title>
	<dc:creator>Kresnoadi, Utari</dc:creator>
	<dc:creator>Salsabila, Najla</dc:creator>
	<dc:creator>Rahmania, Primanda Nur</dc:creator>
	<dc:creator>Adventia, Phara Aster Chandra</dc:creator>
	<dc:creator>Rahmani, Bima Subiakto</dc:creator>
	<dc:creator>Yoda, Nobuhiro</dc:creator>
	<dc:subject xml:lang="en-US">alveolar bone</dc:subject>
	<dc:subject xml:lang="en-US">DFDBBX</dc:subject>
	<dc:subject xml:lang="en-US">Moringa oleifera leaf extract</dc:subject>
	<dc:subject xml:lang="en-US">socket preservation</dc:subject>
	<dc:subject xml:lang="en-US">trabecular area</dc:subject>
	<dc:description xml:lang="en-US">Background: After tooth extraction, alveolar bone resorption occurs naturally, followed by alveolar bone remodeling. Alveolar bone formation is characterized by an increase in density and expansion of the trabecular bone. Socket preservation using a combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) is expected to increase the area of the alveolar bone trabeculae and thus accelerate the process of alveolar bone formation. Purpose: This study aimed to determine if a combination of Moringa oleifera leaf extract and DFDBBX could increase the area of the alveolar bone trabeculae in tooth extraction sockets. Methods: With their lower left incisors extracted, the 56 Cavia cobayas were divided into eight treatment groups according to the material given: polyethylene glycol (PEG), DFDBBX and PEG, Moringa oleifera leaf extract and PEG, and a combination of Moringa oleifera leaf extract, DFDBBX, and PEG. On the seventh and thirtieth days, the Cavia cobayas were sacrificed and examined. Histopathological samples were stained with Hematoxylin-Eosin (HE) to evaluate the trabecula area, and data were analyzed using one-way ANOVA and Tukey HSD. Results: On the thirtieth day, the group that received a combination of Moringa oleifera leaf extract and DFDBBX had the greatest area of alveolar bone trabeculae. Conclusion: A combination of Moringa oleifera leaf extract and DFDBBX induced in the tooth extraction socket can increase the area of the alveolar bone trabeculae.</dc:description>
	<dc:publisher xml:lang="en-US">Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en</dc:publisher>
	<dc:date>2023-03-15</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:format>text/xml</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/MKG/article/view/32053</dc:identifier>
	<dc:identifier>10.20473/j.djmkg.v56.i2.p127-131</dc:identifier>
	<dc:source xml:lang="en-US">Dental Journal (Majalah Kedokteran Gigi); Vol. 56 No. 2 (2023): June 2023; 127-131</dc:source>
	<dc:source>2442-9740</dc:source>
	<dc:source>1978-3728</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/MKG/article/view/32053/24113</dc:relation>
	<dc:relation>https://e-journal.unair.ac.id/MKG/article/view/32053/39916</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 Dental Journal</dc:rights>
	<dc:rights xml:lang="en-US">https://creativecommons.org/licenses/by-sa/4.0</dc:rights>
</oai_dc:dc>