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Quantitative Trait Loci (QTL) Analysis for Production Traits of Birth Weight and Weight 360 days in Backcross Sheep

HAYATI Journal of Biosciences · Vol. 13 No. 1 (2009)

DOI
10.4308/hjb.13.1.31
ISSN
2086-4094, 1978-3019
Terbit
2009-12-01
Penerbit
Bogor Agricultural University, Indonesia
Bahasa
eng

Abstrak

Four half-sib families (n = 382) consisting predominantly of ITT x Merino x Merino backcross progeny, including some F2 progeny were used to analyze QTL for two production traits (Birth weight = BW1 and Body weight at 360 days = BW360). The study exploited differences in weight performance between the Merino and ITT sheep. A total of 141 informative microsatellite markers were used in a genome-wide scan covering the 26 autosomal sheep chromosomes. QTL analysis was conducted online using QTL Express. This study reports the effect of QTL for birth weight on Chromosomes 5 (p < 0.05) at 112cM (0cM-128cM). Location of candidate genes for birth weight was predicted at the region of flanking markers MCM527-BMS1247. A QTL for BW360 days existed on Chromosome 18 (p < 0.01) at 104cM (25.0-125cM). Location of candidate genes related to production traits for body weight 360 days was predicted at the segment of flanking markers of CSSM018-TMR1. Only the QTL on Chromosome 18 retained significance (p < 0.01) under experiment-wide significance testing. This QTL region is being examined for candidate genes by investigating to the homologous human chromosomal segments. Key words: Quantitative trait loci, production traits, birth weight, weigh 360, backcross sheep

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  • IPB University
  • National Research and Innovation Agency
  • Syarif Hidayatullah State Islamic University Jakarta
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Rekan penulisOrganisasiArtikel bersama
Maria UlfahIPB University2
Dyah Perwitasari‐FarajallahIPB University2
Achmad FarajallahIPB University2
Apri IriantoIPB University1
Asep GunawanIPB University1
Widya Pintaka Bayu PutraAfiliasi tidak diketahui1
Daud SamsudewaAfiliasi tidak diketahui1
M. A. PagalaAfiliasi tidak diketahui1
C. SumatriAfiliasi tidak diketahui1
S. MurtiniAfiliasi tidak diketahui1
Melfa Andraini AgathaIPB University1
Sofyan SjafIPB University1
Alfiyan AchmadIPB University1
Achmad AlfiyanIPB University1
Nahrowi NahrowiSyarif Hidayatullah State Islamic University Jakarta1
Rudy PriyantoIPB University1
Syahruddin SaidNational Research and Innovation Agency1
Dinda Ayu Permata SariIPB University1

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Sumber metadata: OAI-PMH (metadata jurnal) http://journal.ipb.ac.id/index.php/hayati/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Quantitative Trait Loci (QTL) Analysis for Production Traits of Birth Weight and Weight 360 days in Backcross Sheep</dc:title>
	<dc:creator xml:lang="en">MARGAWATI, ENDANG TRI</dc:creator>
	<dc:creator xml:lang="en">RAADSMA, HERMAN WILLEM</dc:creator>
	<dc:creator xml:lang="en">MARTOJO, HARIMURTI</dc:creator>
	<dc:creator xml:lang="en">SUBANDRIYO, SUBANDRIYO</dc:creator>
	<dc:creator xml:lang="en">MULADNO, MULADNO</dc:creator>
	<dc:description xml:lang="en">Four half-sib families (n = 382) consisting predominantly of ITT x Merino x Merino backcross progeny, including some F2 progeny were used to analyze QTL for two production traits (Birth weight = BW1 and Body weight at 360 days = BW360). The study exploited differences in weight performance between the Merino and ITT sheep. A total of 141 informative microsatellite markers were used in a genome-wide scan covering the 26 autosomal sheep chromosomes. QTL analysis was conducted online using QTL Express. This study reports the effect of QTL for birth weight on Chromosomes 5 (p &lt; 0.05) at 112cM (0cM-128cM). Location of candidate genes for birth weight was predicted at the region of flanking markers MCM527-BMS1247. A QTL for BW360 days existed on Chromosome 18 (p &lt; 0.01) at 104cM (25.0-125cM). Location of candidate genes related to production traits for body weight 360 days was predicted at the segment of flanking markers of CSSM018-TMR1. Only the QTL on Chromosome 18 retained significance (p &lt; 0.01) under experiment-wide significance testing. This QTL region is being examined for candidate genes by investigating to the homologous human chromosomal segments. Key words: Quantitative trait loci, production traits, birth weight, weigh 360, backcross sheep </dc:description>
	<dc:publisher xml:lang="en">Bogor Agricultural University, Indonesia</dc:publisher>
	<dc:date>2009-12-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://journal.ipb.ac.id/hayati/article/view/201</dc:identifier>
	<dc:identifier>10.4308/hjb.13.1.31</dc:identifier>
	<dc:source xml:lang="en">HAYATI Journal of Biosciences; Vol. 13 No. 1 (2006): March 2006; 31</dc:source>
	<dc:source>2086-4094</dc:source>
	<dc:source>1978-3019</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://journal.ipb.ac.id/hayati/article/view/201/67</dc:relation>
</oai_dc:dc>