Melola Discovery

← Melola Discovery

Jurnal SINTA 1

Phage FR38 Treatment on Sprague Dawley Rat Inferred from Blood Parameters and Organ Systems

HAYATI Journal of Biosciences · Vol. 19 No. 3 (2012)

DOI
10.4308/hjb.19.3.131
ISSN
2086-4094, 1978-3019
Terbit
2012-10-15
Penerbit
Bogor Agricultural University, Indonesia
Bahasa
eng

Abstrak

The ability of phage FR38 to lysis indigenous Salmonella P38 from feces of diarrheal patient has been studied. However, effects of phage FR38 on organ system were not revealed as yet. This study was conducted to observe the effect of phage FR38 on blood chemistry, kidney functions, and liver functions. Twelve Sprague-Dawley rats were used as a model for this study that were divided into two groups; (i) control and (ii) treated group with phage FR38. For treated phage group, each rat was administered by 5 ml/kg bw of 1.59·107 pfu/ml of phage intragastric. The blood parameters were analysed on day 16. The results revealed that body and organs weight, erythrocyte, hematocrit, hemoglobin, leukocyte, total protein, creatinine, SGOT, and SGPT of phage treatment rats were not significantly different with the control rats on day 16 (P > 0.05). Therefore, this study showed was no effect of phage FR38 on body weight, blood chemistry, kidney and liver functions of the rat (P > 0.05).

Kata kunci

Jaringan kolaborasi para penulis

40 penulis · 94 tautan kepenulisan bersama · 24 lintas organisasi · menampilkan 40 yang paling banyak terhubung

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

  • IPB University
  • Lampung University
  • Universitas Gadjah Mada
  • Universitas Airlangga
  • Hasanuddin University
  • Sebelas Maret University
  • Universitas Papua
  • Organisasi lain
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
  • Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Denny Widaya LukmanIPB University4
Nisa Rachmania MubarikIPB University2
Bambang SuryobrotoIPB University2
Alex HartanaIPB University2
Yulin LestariIPB University2
Rika Indri AstutiIPB University2
Herwin PisestyaniIPB University2
Suharyono SuharyonoUniversitas Airlangga1
Eka Z. SastianiLampung University1
Murhadi MurhadiLampung University1
Neti YulianaLampung University1
I. SudirmanAfiliasi tidak diketahui1
Ratmawati MalakaHasanuddin University1
Wahniyathi HattaAfiliasi tidak diketahui1
Siti Muslimah WidyastutiUniversitas Gadjah Mada1
Sebastian MarginoUniversitas Gadjah Mada1
Tetri WidiyaniSebelas Maret University1
Elda Irma Jeanne Joice KawulurUniversitas Papua1
Anik KusmiatunIPB University1
İman RusmanaIPB University1
Min RahminiwatiIPB University1
Budi WirawanIPB University1
Zulhaerati ZulhaeratiIPB University1
Ririn Herni PutriIPB University1
Aris Tri WahyudiIPB University1
Siti SholekhaIPB University1
Akhmad Endang Zainal HasanIPB University1
Ni Putu Ratna Ayu KrishantiNational Research and Innovation Agency1
Firda Sri EfendiAfiliasi tidak diketahui1
Chandra Utami WirawatiAfiliasi tidak diketahui1
Ietje WientarsihIPB University1
Eko Agus SrihantoMinistry of Agriculture1
Widagdo Sri NugrohoUniversitas Gadjah Mada1
E. SetiyaningsihAfiliasi tidak diketahui1
Ewald UsleberAfiliasi tidak diketahui1
Ardilasunu WicaksonoIPB University1
Nada Nursaffana RamadhaniIPB University1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) http://journal.ipb.ac.id/index.php/hayati/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Phage FR38 Treatment on Sprague Dawley Rat Inferred from Blood Parameters and Organ Systems</dc:title>
	<dc:creator xml:lang="en">SARTIKA, DEWI</dc:creator>
	<dc:creator xml:lang="en">BUDIARTI, SRI</dc:creator>
	<dc:creator xml:lang="en">SUDARWANTO, MIRNAWATI</dc:creator>
	<dc:subject xml:lang="en">phage FR38</dc:subject>
	<dc:subject xml:lang="en">blood chemistry</dc:subject>
	<dc:subject xml:lang="en">kidney functions</dc:subject>
	<dc:subject xml:lang="en">liver functions</dc:subject>
	<dc:description xml:lang="en">The ability of phage FR38 to lysis indigenous Salmonella P38 from feces of diarrheal patient has been studied. However, effects of phage FR38 on organ system were not revealed as yet. This study was conducted to observe the effect of phage FR38 on blood chemistry, kidney functions, and liver functions. Twelve Sprague-Dawley rats were used as a model for this study that were divided into two groups; (i) control and (ii) treated group with phage FR38. For treated phage group, each rat was administered by 5 ml/kg bw of 1.59·107 pfu/ml of phage intragastric. The blood parameters were analysed on day 16. The results revealed that body and organs weight, erythrocyte, hematocrit, hemoglobin, leukocyte, total protein, creatinine, SGOT, and SGPT of phage treatment rats were not significantly different with the control rats on day 16 (P &gt; 0.05). Therefore, this study showed was no effect of phage FR38 on body weight, blood chemistry, kidney and liver functions of the rat (P &gt; 0.05).</dc:description>
	<dc:publisher xml:lang="en">Bogor Agricultural University, Indonesia</dc:publisher>
	<dc:date>2012-10-15</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://journal.ipb.ac.id/hayati/article/view/5629</dc:identifier>
	<dc:identifier>10.4308/hjb.19.3.131</dc:identifier>
	<dc:source xml:lang="en">HAYATI Journal of Biosciences; Vol. 19 No. 3 (2012): September 2012; 131</dc:source>
	<dc:source>2086-4094</dc:source>
	<dc:source>1978-3019</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://journal.ipb.ac.id/hayati/article/view/5629/4268</dc:relation>
</oai_dc:dc>