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Optimization Extraction of Xylocarpus granatum Stem as Antioxidant and Antiglycation

HAYATI Journal of Biosciences · Vol. 26 No. 2 (2019)

DOI
10.4308/hjb.26.2.50
ISSN
2086-4094, 1978-3019
Terbit
2019-10-27
Penerbit
Bogor Agricultural University, Indonesia
Bahasa
eng

Abstrak

Xylocarpus granatum is an Indonesian plant that has bioactives content of phenols and high antioxidant activity on it. The aim of this research was to determine the optimum condition maceration for Xylocarpus granatum stem as antioxidant and antiglycation. The optimum conditions of maceration were effected by the extraction variables (concentration, sample/solvent ratio, extraction time) were evaluated using surface response method. The optimum condition was determined from the recovery of the respons. The optimum condition of maceration is predicted to be achieved when the solvent concentration is 52.25%, the extraction time is 15.92 hours, sample/solvent ratio is 1 g/9 ml with the response (yield, total phenol content, flavonoid, inhibition for 2,2’-diphenylpicryl hydrazyl, capacity of 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), and inhibition antiglycation were 12.81%, 1.95 mg of gallic acid/g extract, 62.33 μg quercetin/g extract, 41.11%, 0.71 TEAC, and 112.33%, respectively). Optimization extraction conditions shows that the extraction variables have significant effect on respons so it can reduce the extraction time, economic, and produce high bioactivite constituens.

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  • Bandung Institute of Technology
  • University of Hawaiʻi at Mānoa
  • National Research and Innovation Agency
  • Sultan Ageng Tirtayasa University
  • State University of Semarang
  • Nara Institute of Science and Technology
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Rekan penulisOrganisasiArtikel bersama
Setyanto Tri WahyudiIPB University3
I Made SumertajayaIPB University2
Nampiah SukarnoIPB University2
Latifah Kosim DarusmanIPB University2
Mashuri WaiteUniversity of Hawaiʻi at Mānoa2
Muhammad Eka PrastyaNational Research and Innovation Agency2
Shadila Fira AsokaIPB University2
Bambang RiyantoIPB University2
Fikry AwaluddinIPB University2
Auliya IlmiawatiIPB University2
Asep SaefuddinIPB University1
Viarti EminitaAfiliasi tidak diketahui1
Kusman SadikIPB University1
Aji Hamim WigenaIPB University1
Faula ArinaSultan Ageng Tirtayasa University1
Nindya WulandariIPB University1
Erfiani ErfianiIPB University1
Irzaman IrzamanIPB University1
Budi SusetyoIPB University1
Ratna Nur Mustika SanusiState University of Semarang1
I Nyoman Pugeg AryanthaBandung Institute of Technology1
Utut WidyastutiIPB University1
Rohani Cinta Badia GintingIPB University1
Sihegiko KanayaNara Institute of Science and Technology1
Sintho Wahyuning ArdieIPB University1
Soekisman TjitrosoedirdjoSoutheast Asian Regional Centre for Tropical Biology1
Za’aziza Ridha JuliaIPB University1
Muhamad İnsanuBandung Institute of Technology1
Abdul RohmanUniversitas Gadjah Mada1
Mohamad RafiIPB University1
Alfi Hudatul KaromahIPB University1
Dewi Anggraini SeptaningsihIPB University1
Nanik Siti AminahUniversitas Airlangga1
Sri ListiyowatiIPB University1
Rika Indri AstutiIPB University1
Nadila Fany AshafaniIPB University1
Erma SuryantiSumatera Institute of Technology1

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Sumber metadata: OAI-PMH (metadata jurnal) http://journal.ipb.ac.id/index.php/hayati/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Optimization Extraction of Xylocarpus granatum Stem as Antioxidant and Antiglycation</dc:title>
	<dc:creator xml:lang="en">Sapitri, Eka Winarni</dc:creator>
	<dc:creator xml:lang="en">Batubara, Irmanida</dc:creator>
	<dc:creator xml:lang="en">Syafitri, Utami Dyah</dc:creator>
	<dc:subject xml:lang="en">ABTS</dc:subject>
	<dc:subject xml:lang="en">antiglycation</dc:subject>
	<dc:subject xml:lang="en">DPPH</dc:subject>
	<dc:subject xml:lang="en">stem of Xylocarous granatum</dc:subject>
	<dc:description xml:lang="en">Xylocarpus granatum is an Indonesian plant that has bioactives content of phenols and high antioxidant activity on it. The aim of this research was to determine the optimum condition maceration for Xylocarpus granatum stem as antioxidant and antiglycation. The optimum conditions of maceration were effected by the extraction variables (concentration, sample/solvent ratio, extraction time) were evaluated using surface response method. The optimum condition was determined from the recovery of the respons. The optimum condition of maceration is predicted to be achieved when the solvent concentration is 52.25%, the extraction time is 15.92 hours, sample/solvent ratio is 1 g/9 ml with the response (yield, total phenol content, flavonoid, inhibition for 2,2’-diphenylpicryl hydrazyl, capacity of 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), and inhibition antiglycation were 12.81%, 1.95 mg of gallic acid/g extract, 62.33 μg quercetin/g extract, 41.11%, 0.71 TEAC, and 112.33%, respectively). Optimization extraction conditions shows that the extraction variables have significant effect on respons so it can reduce the extraction time, economic, and produce high bioactivite constituens.</dc:description>
	<dc:publisher xml:lang="en">Bogor Agricultural University, Indonesia</dc:publisher>
	<dc:date>2019-10-27</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://journal.ipb.ac.id/hayati/article/view/27973</dc:identifier>
	<dc:identifier>10.4308/hjb.26.2.50</dc:identifier>
	<dc:source xml:lang="en">HAYATI Journal of Biosciences; Vol. 26 No. 2 (2019): April 2019; 50</dc:source>
	<dc:source>2086-4094</dc:source>
	<dc:source>1978-3019</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://journal.ipb.ac.id/hayati/article/view/27973/pdf</dc:relation>
</oai_dc:dc>