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The Potency of Anadara nodifera Shell as Natural Testosterone Booster for Male Canary (Seriunus canaria)

HAYATI Journal of Biosciences · Vol. 29 No. 1 (2021) · hlm. 107–113

DOI
10.4308/hjb.29.1.107-113
ISSN
2086-4094, 1978-3019
Terbit
2021-12-08
Penerbit
Bogor Agricultural University, Indonesia
Bahasa
eng

Abstrak

Anadara clam shell contains high Zinc. This microelement is recognised as acting natural aromatase blocker (NAB) that capable of boosting testosterone level. The aim of this study was to evaluates the testosterone level of Canaries following Anadara nodifera administration. Adult male Canaries (n = 27) were group into 3 with 9 repetition of each i.e T0 [control, was given by Carboxymethyl Cellulose Sodium (Na-CMC)], T1 (Zinc Sulphate 0.013 mg/30 g BW), and T2 (NAB 0.3 mg/30 g BW). The T2 treatment was NAB or shell powder of Anadara nodifera which was diluted 1:1 in Na-CMC. The birds were treated orally for 21 days. The complete blood cell count was performed in a haemo analyser except the erythrocyte was calculated manually in the Improved Neubauer counting chamber. Testosterone level was measured in ELISA. Subsequently gen CYP19 aromatase in syrinx, brain and testis were identified employing IHC and descriptively analysed. The result indicated significant elevated level of testosterone (p 0.05). To conclude, Anadara nodifera at 0.3 mg/30 g BW was capable of acting as NAB to promote testosterone level. This was confirmed by the reduction of CYP19 aromatase gene receptors in syrinx, brain and testis. However NAB treatment was not significantly affecting routine blood profile.

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33 penulis · 88 tautan kepenulisan bersama · 12 lintas organisasi

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  • Universitas Gadjah Mada
  • IPB University
  • Bandung Institute of Technology
  • University of Indonesia
  • Mulawarman University
  • Jenderal Soedirman University
  • Universitas Al-Azhar Indonesia
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Rekan penulisOrganisasiArtikel bersama
Hanni GarminiaBandung Institute of Technology3
Akhmad Abror As SidiqiUniversitas Gadjah Mada3
Hera MaheshwariAfiliasi tidak diketahui2
Rarastoeti PratiwiUniversitas Gadjah Mada2
Sabarinsyah SabarinsyahBandung Institute of Technology2
TUTY LASWARDI YUSUFAfiliasi tidak diketahui1
ERIC HAYESAfiliasi tidak diketahui1
LUTHFIRALDA SJAHFIRDIAfiliasi tidak diketahui1
DONDIN SAJUTHIAfiliasi tidak diketahui1
Hadi Sukardi AlikodraAfiliasi tidak diketahui1
Bambang PurwantaraIPB University1
Dondin SajuthiIPB University1
Reviany WidjajakusumaIPB University1
Luthfiralda SjahfirdiUniversity of Indonesia1
Asmarani KusumawatiAfiliasi tidak diketahui1
Penny Humaidah HamidAfiliasi tidak diketahui1
Laurentius Hartanto NugrohoUniversitas Gadjah Mada1
Sukarti MoeljopawiroUniversitas Gadjah Mada1
Retno AryaniMulawarman University1
Bambang RetnoajiUniversitas Gadjah Mada1
Endah Sri PalupiJenderal Soedirman University1
Firman AlamsyahUniversitas Al-Azhar Indonesia1
Warsito Purwo TarunoAfiliasi tidak diketahui1
Agah Drajat GarnadiIPB University1
Sisilia SylvianiPadjadjaran University1
Aminuddin MustaffaSultan Zainal Abidin University1
Vita MahardhikaUniversitas Negeri Surabaya1

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Sumber metadata: OAI-PMH (metadata jurnal) http://journal.ipb.ac.id/index.php/hayati/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">The Potency of Anadara nodifera Shell as Natural Testosterone Booster for Male Canary (Seriunus canaria)</dc:title>
	<dc:creator xml:lang="en">Astuti, Pudji</dc:creator>
	<dc:creator xml:lang="en">Putra, Muhammad Naufal Prayitno </dc:creator>
	<dc:creator xml:lang="en">Shiddiq, Muhammad Fariz Ash </dc:creator>
	<dc:creator xml:lang="en">Yuneldi, Rizki Fitrawan </dc:creator>
	<dc:creator xml:lang="en">Airin, Claude Mona</dc:creator>
	<dc:creator xml:lang="en">Sarmin, Sarmin</dc:creator>
	<dc:description xml:lang="en">Anadara clam shell contains high Zinc. This microelement is recognised as acting natural aromatase blocker (NAB) that capable of boosting testosterone level. The aim of this study was to evaluates the testosterone level of Canaries following Anadara nodifera administration. Adult male Canaries (n = 27) were group into 3 with 9 repetition of each i.e T0 [control, was given by Carboxymethyl Cellulose Sodium (Na-CMC)], T1 (Zinc Sulphate 0.013 mg/30 g BW), and T2 (NAB 0.3 mg/30 g BW). The T2 treatment was NAB or shell powder of Anadara nodifera which was diluted 1:1 in Na-CMC. The birds were treated orally for 21 days. The complete blood cell count was performed in a haemo analyser except the erythrocyte was calculated manually in the Improved Neubauer counting chamber. Testosterone level was measured in ELISA. Subsequently gen CYP19 aromatase in syrinx, brain and testis were identified employing IHC and descriptively analysed. The result indicated significant elevated level of testosterone (p&amp;lt;0.05). The expression of CYP19 aromatase receptor was depressed in syrinx, brain and testis. However there was no significant changes on the blood profile (p&amp;gt;0.05). To conclude, Anadara nodifera at 0.3 mg/30 g BW was capable of acting as NAB to promote testosterone level. This was confirmed by the reduction of CYP19 aromatase gene receptors in syrinx, brain and testis. However NAB treatment was not significantly affecting routine blood profile.</dc:description>
	<dc:publisher xml:lang="en">Bogor Agricultural University, Indonesia</dc:publisher>
	<dc:date>2021-12-08</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en">Peer-reviewed Article</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>http://journal.ipb.ac.id/hayati/article/view/37318</dc:identifier>
	<dc:identifier>10.4308/hjb.29.1.107-113</dc:identifier>
	<dc:source xml:lang="en">HAYATI Journal of Biosciences; Vol. 29 No. 1 (2022): January 2022; 107-113</dc:source>
	<dc:source>2086-4094</dc:source>
	<dc:source>1978-3019</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>http://journal.ipb.ac.id/hayati/article/view/37318/22582</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2021 Pudji Astuti, Muhammad Naufal Prayitno  Putra, Muhammad Fariz Ash  Shiddiq, Rizki Fitrawan  Yuneldi, Claude Mona Airin, Sarmin Sarmin</dc:rights>
</oai_dc:dc>