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Intraprocedural Stent Thrombosis During Percutaneous Coronary Intervention: How to Predict

Heart Science Journal · Vol. 3 No. 2 (2022) · hlm. 35–39

DOI
10.21776/ub.hsj.2022.003.02.7
ISSN
2721-9984, 2721-9976
Terbit
2022-04-30
Penerbit
Universitas Brawijaya
Bahasa
en

Abstrak

Background: Intraprocedural stent thrombosis (IPST) during percutaneous coronary intervention (PCI) is an uncommon event that results in a poor outcome including STEMI and sudden cardiac death. Concerns about an increased risk of stent thrombosis with drug-eluting stents (DES) continue, even though the incidence, timing, and predictors of stent thrombosis with DES have not been identified.Objective: This study aimed to describe the diagnosis and management of Intraprocedural Stent Thrombosis.Case presentation: We will discuss a 49 year-old male brought to our hospital because of chest pain while doing moderate activity. One month prior to admission, he had history of acute coronary syndrome and 1 DES on right coronary artery was placed. Ticagrelor and aspirin were routinely consumed as dual antiplatelet therapy. The patient was diagnosed with intraprocedural stent thrombosis during PCI with the evidence of intra-catheter thrombosis and ST segment elevations seen in the ECG monitor. We treat the patient with Ticagrelor 180 mg loading dose and intracoronary unfractionated heparin (UFH) during procedure continued with continuous infusion until 24 hours. No event of subsequent acute coronary syndrome was observed.Conclusion: Intraprocedural Stent Thrombosis was a strong predictor of mortality in STEMI patients. This case showed that the present widespread use of DES instead of BMS for coronary implantation although decreased the future risk of repeat revascularization, increased the risk of thrombosis. Prior risk stratification, potent early antiplatelet treatment and anticoagulant of choice with UFH might be used to reduce the risk of thrombosis in STEMI patients undergoing stent implantation.

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  • University of Brawijaya
  • RSUD Prof. Dr. Saiful Anwar Malang
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Rekan penulisOrganisasiArtikel bersama
Cholid Tri TjahjonoUniversity of Brawijaya26
Indra PrasetyaUniversity of Brawijaya25
Setyasih AnjarwaniUniversity of Brawijaya25
Anna Fuji RahimahUniversity of Brawijaya23
Ardian RizalUniversity of Brawijaya21
Novi KurnianingsihUniversity of Brawijaya19
Djanggan SargowoUniversity of Brawijaya16
Sasmojo WiditoUniversity of Brawijaya16
Yoga WaranugrahaUniversity of Brawijaya11
Heny MartiniUniversity of Brawijaya11
Muhammad Rizki FadlanUniversity of Brawijaya6
Putri Annisa KamilaUniversity of Brawijaya5
Adhika Prastya WikanandaUniversity of Brawijaya4
Tri AstiawatiUniversity of Brawijaya4
Dadang HendrawanUniversity of Brawijaya4
Hayla Iqda MillisaniUniversity of Brawijaya4
Fandy HazzyUniversity of Brawijaya3
Wella KarolinaUniversity of Brawijaya3
Oktivani Adelathifa RahmaUniversity of Brawijaya3
Olivia HandayaniUniversity of Brawijaya3
Dea Arie KurniawanUniversity of Brawijaya3
Imelda KrisnasariUniversity of Brawijaya3
Ayu Asri Devi AdityawatiUniversity of Brawijaya3
Seprian WidasmaraUniversity of Brawijaya3
Valerinna YogibuanaAfiliasi tidak diketahui3
Valerinna Yogibuana Swastika PutriUniversity of Brawijaya3
Shalahuddin Suryo BaskoroUniversity of Brawijaya3
Nikhen NoverikeUniversity of Brawijaya3
Zhafran VeliawanUniversity of Brawijaya3
Veny KurniawatiUniversity of Brawijaya2
Tonny AdriyantoUniversity of Brawijaya2
Jonny Karunia FajarUniversity of Brawijaya2
Fahmy RusnantaUniversity of Brawijaya2
Fitranti Suciati LaitupaUniversity of Brawijaya2
Oktafin Srywati PamunaUniversity of Brawijaya2
Liemena Harold AdrianRSUD Prof. Dr. Saiful Anwar Malang2

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Intraprocedural Stent Thrombosis During Percutaneous Coronary Intervention: How to Predict</dc:title>
	<dc:creator xml:lang="en">Aji, Bayu</dc:creator>
	<dc:creator xml:lang="en">Rohman, Mohammad Saifur</dc:creator>
	<dc:creator xml:lang="en">Satrijo, Budi</dc:creator>
	<dc:creator xml:lang="en">Wibisono, Arief</dc:creator>
	<dc:subject xml:lang="en">Stent Thrombosis</dc:subject>
	<dc:subject xml:lang="en">Percutaneous Coronary Intervention</dc:subject>
	<dc:description xml:lang="en">Background: Intraprocedural stent thrombosis (IPST) during percutaneous coronary intervention (PCI) is an uncommon event that results in a poor outcome including STEMI and sudden cardiac death. Concerns about an increased risk of stent thrombosis with drug-eluting stents (DES) continue, even though the incidence, timing, and predictors of stent thrombosis with DES have not been identified.Objective: This study aimed to describe the diagnosis and management of Intraprocedural Stent Thrombosis.Case presentation: We will discuss a 49 year-old male brought to our hospital because of chest pain while doing moderate activity. One month prior to admission, he had history of acute coronary syndrome and 1 DES on right coronary artery was placed. Ticagrelor and aspirin were routinely consumed as dual antiplatelet therapy. The patient was diagnosed with intraprocedural stent thrombosis during PCI with the evidence of intra-catheter thrombosis and ST segment elevations seen in the ECG monitor. We treat the patient with Ticagrelor 180 mg loading dose and intracoronary unfractionated heparin (UFH) during procedure continued with continuous infusion until 24 hours. No event of subsequent acute coronary syndrome was observed.Conclusion: Intraprocedural Stent Thrombosis was a strong predictor of mortality in STEMI patients. This case showed that the present widespread use of DES instead of BMS for coronary implantation although decreased the future risk of repeat revascularization, increased the risk of thrombosis. Prior risk stratification, potent early antiplatelet treatment and anticoagulant of choice with UFH might be used to reduce the risk of thrombosis in STEMI patients undergoing stent implantation.</dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2022-04-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/1328</dc:identifier>
	<dc:identifier>10.21776/ub.hsj.2022.003.02.7</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 3 No. 2 (2022): Improving ST-Elevation Myocardial Infraction Patients Prognosis; 35-39</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2022.003.02</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/1328/261</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2022 Bayu Aji</dc:rights>
</oai_dc:dc>