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Idiopathic Pulmonary Arterial Hypertension Newly Diagnosed in Pregnancy with Anemia and Threatened Preterm Labor

Heart Science Journal · Vol. 3 No. 4 (2022) · hlm. 35–39

DOI
10.21776/ub.hsj.2022.003.04.7
ISSN
2721-9984, 2721-9976
Terbit
2022-10-01
Penerbit
Universitas Brawijaya
Bahasa
en

Abstrak

Background: Pulmonary hypertension (PH) is a rare cardiovascular disorder that leads to right heart failure (RHF). Although most PH occurs secondary to congenital heart disease (CHD), PH can occur primarily due to pulmonary arterial vasculature abnormalities, known as Idiopathic pulmonary arterial hypertension (IPAH). In addition, the physiologic changes during pregnancy can potentially lead to worsening PAH and confer a poor prognosis. Therefore, when the mother refuses termination, a multidisciplinary team should manage the pregnancy and delivery to improve maternal and fetal outcomes.Objectives: This case report aimed to describe the importance of early diagnosis and treatment in PAH.Case reports: We reported a case of a 24-year-old woman with idiopathic pulmonary arterial hypertension (IPAH) that was newly diagnosed at 25 weeks of pregnancy and previously misdiagnosed with patent ductus arteriosus (PDA). This pregnancy was complicated with anemia and threatened preterm labor. Sildenafil was used as a vasodilator to reduce the symptoms of PAH. Unfortunately, the pregnancy was terminated at 29 weeks because of PPROM after considering giving lung maturation and neuroprotectant to the fetus. The patient was discharged without complication, but the baby died after eight days of intensive care due to HMD II, which led to respiratory failure.Conclusion: PAH in pregnancy is a life-threatening condition if untreated. Continuous treatments can help control the symptoms and avoid further complications for both mother and baby.

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Rekan penulisOrganisasiArtikel bersama
Anna Fuji RahimahUniversity of Brawijaya22
Cholid Tri TjahjonoUniversity of Brawijaya21
Ardian RizalUniversity of Brawijaya20
Indra PrasetyaUniversity of Brawijaya20
Setyasih AnjarwaniUniversity of Brawijaya19
Budi SatrijoUniversity of Brawijaya18
Novi KurnianingsihUniversity of Brawijaya13
Heny MartiniUniversity of Brawijaya13
Yoga WaranugrahaUniversity of Brawijaya9
Djanggan SargowoUniversity of Brawijaya9
Sasmojo WiditoUniversity of Brawijaya9
Wella KarolinaUniversity of Brawijaya7
Adhika Prastya WikanandaUniversity of Brawijaya4
Tri AstiawatiUniversity of Brawijaya4
Putri Annisa KamilaUniversity of Brawijaya3
Dadang HendrawanUniversity of Brawijaya3
Muhammad Rizki FadlanUniversity of Brawijaya3
Fandy HazzyUniversity of Brawijaya3
Hayla Iqda MillisaniUniversity of Brawijaya3
Oktivani Adelathifa RahmaUniversity of Brawijaya3
Nikhen NoverikeUniversity of Brawijaya3
Veny KurniawatiUniversity of Brawijaya2
Tonny AdriyantoUniversity of Brawijaya2
Jonny Karunia FajarUniversity of Brawijaya2
Olivia HandayaniUniversity of Brawijaya2
Fahmy RusnantaUniversity of Brawijaya2
Fitranti Suciati LaitupaUniversity of Brawijaya2
Oktafin Srywati PamunaUniversity of Brawijaya2
Anna Fuji RahimahAfiliasi tidak diketahui2
Imelda KrisnasariUniversity of Brawijaya2
Ratna PancasariUniversity of Brawijaya2
Ayu Asri Devi AdityawatiUniversity of Brawijaya2
Krishna Ari NugrahaUniversity of Brawijaya2
Dea Arie KurniawanUniversity of Brawijaya2

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Sumber metadata: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Idiopathic Pulmonary Arterial Hypertension Newly Diagnosed in Pregnancy with Anemia and Threatened Preterm Labor</dc:title>
	<dc:creator xml:lang="en">Harumsari, Stefani</dc:creator>
	<dc:creator xml:lang="en">Rahardjo, Bambang</dc:creator>
	<dc:creator xml:lang="en">Prasetyorini, Nugrahanti</dc:creator>
	<dc:creator xml:lang="en">Dwijayasa, Pande Made</dc:creator>
	<dc:creator xml:lang="en">Yogibuana, Valerinna</dc:creator>
	<dc:creator xml:lang="en">Rohman, Mohammad Saifur</dc:creator>
	<dc:subject xml:lang="en">IPAH</dc:subject>
	<dc:subject xml:lang="en">PH</dc:subject>
	<dc:subject xml:lang="en">pregnancy</dc:subject>
	<dc:subject xml:lang="en">anemia</dc:subject>
	<dc:subject xml:lang="en">PPROM</dc:subject>
	<dc:description xml:lang="en">Background: Pulmonary hypertension (PH) is a rare cardiovascular disorder that leads to right heart failure (RHF). Although most PH occurs secondary to congenital heart disease (CHD), PH can occur primarily due to pulmonary arterial vasculature abnormalities, known as Idiopathic pulmonary arterial hypertension (IPAH). In addition, the physiologic changes during pregnancy can potentially lead to worsening PAH and confer a poor prognosis. Therefore, when the mother refuses termination, a multidisciplinary team should manage the pregnancy and delivery to improve maternal and fetal outcomes.Objectives: This case report aimed to describe the importance of early diagnosis and treatment in PAH.Case reports: We reported a case of a 24-year-old woman with idiopathic pulmonary arterial hypertension (IPAH) that was newly diagnosed at 25 weeks of pregnancy and previously misdiagnosed with patent ductus arteriosus (PDA). This pregnancy was complicated with anemia and threatened preterm labor. Sildenafil was used as a vasodilator to reduce the symptoms of PAH. Unfortunately, the pregnancy was terminated at 29 weeks because of PPROM after considering giving lung maturation and neuroprotectant to the fetus. The patient was discharged without complication, but the baby died after eight days of intensive care due to HMD II, which led to respiratory failure.Conclusion: PAH in pregnancy is a life-threatening condition if untreated. Continuous treatments can help control the symptoms and avoid further complications for both mother and baby.</dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2022-10-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/1363</dc:identifier>
	<dc:identifier>10.21776/ub.hsj.2022.003.04.7</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 3 No. 4 (2022): Prevention, Screening dan Rehabilitation : The Back Bone of Quality Care Improvement in CVD Management; 35-39</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2022.003.04</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/1363/246</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2022 Stefani Harumsari, Bambang Rahardjo, Valerinna Yogibuana, Mohammad Saifur Rohman</dc:rights>
</oai_dc:dc>