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Left Ventricular Hypertrophy and Clinical Outcomes in Heart Failure Patients Based on Hypertension Subtypes: Insights from a Tertiary Hospital Heart Failure Registry in Malang, Indonesia

Heart Science Journal · Vol. 4 No. 2 (2023) · hlm. 18–22

DOI
10.21776/ub.hsj.2023.004.02.4
ISSN
2721-9984, 2721-9976
Terbit
2023-04-01
Penerbit
Universitas Brawijaya
Bahasa
en

Abstrak

BackgroundLeft ventricular hypertrophy (LVH) is a maladaptive response to chronic pressure overload and an important risk factor sudden death in patients with heart failure. Previous studies show that LVH is a risk factor for systolic heart failure. It’s interesting to examine whether Isolated Systolic Hypertension (ISH) in the presence of LVH contribute to clinical outcome.Objective: The aims of this study to examined association of ISH with cardiovascular outcomes and to examined associations of ISH and LVH in Heart failure registry patientMethods: A total of 120 subject’s were collected from Saiful Anwar Heart Failure Registry from January 2019 to December 2019. All participants were individually interviewed with a structured questionnaire for collecting baseline characteristic. Subject were classified into 2 group of hypertension (ISH and Systolic Diastolic Hypertension (SDH)). ISH based on the criteria of SBP ≥ 140 and DBP < 90 mmHg and SDH based on SBP ≥ 140 and DBP ≥ 90 mmHg. The EF and volumes were measured with 2D-biplane Simpson's method by measured as a standart mannerResult’s: ISH commonly found among older hypertensive patients than SDH (Mean age 61,23±11,2 yo vs 53,52±11,1 yo, respectively, p<0,04)). LVH was more prevalence among ISH than SDH. No difference in clinical outcome such as in hospital mortality, Rehospitalization, and Lengt of stay were observed in both groups. Complication of hypertension was similar in both groups such as stroke, Myocardial Infarct, and Chronic Kidney Disease. Intrestingly, no difference also observe in compliance to the drug between ISH and SDH. We also examined subgroup analysis of subject’s with ISH. There was no statistically significant difference in clinical outcome between ISH with LVH and ISH without LVH.Conclusion: In this study, we suggest that ISH more common in older patient with HF than SDH but had similar associations with cardiovascular mortality and rehospitalization. ISH was associated with a higher prevalence of left ventricular hypertrophy than SDH.

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  • University of Brawijaya
  • RSUD Prof. Dr. Saiful Anwar Malang
  • Sapienza University of Rome
  • Afiliasi tidak diketahui
  • Organisasi berbeda
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Rekan penulisOrganisasiArtikel bersama
Mohammad Saifur RohmanUniversity of Brawijaya21
Setyasih AnjarwaniUniversity of Brawijaya12
Cholid Tri TjahjonoUniversity of Brawijaya11
Indra PrasetyaUniversity of Brawijaya10
Djanggan SargowoUniversity of Brawijaya9
Sasmojo WiditoUniversity of Brawijaya8
Anna Fuji RahimahUniversity of Brawijaya8
Novi KurnianingsihUniversity of Brawijaya7
Yoga WaranugrahaUniversity of Brawijaya5
Ardian RizalUniversity of Brawijaya4
Putri Annisa KamilaUniversity of Brawijaya3
Heny MartiniUniversity of Brawijaya3
Muhammad Saifur RohmanAfiliasi tidak diketahui3
Marco FilanoUniversity of Brawijaya3
Merlita HerbaniUniversity of Brawijaya3
Dea Arie KurniawanUniversity of Brawijaya2
Anna Fuji RahimahAfiliasi tidak diketahui2
Harris KristantoUniversity of Brawijaya2
Valerinna Yogibuana Swastika PutriUniversity of Brawijaya2
Hendrawati HendrawatiUniversity of Brawijaya2
Liemena Harold AdrianRSUD Prof. Dr. Saiful Anwar Malang2
Aditya Reza PratamaUniversity of Brawijaya2
Yuri AfifahUniversity of Brawijaya2
Yoseph Budi UtomoUniversity of Brawijaya1
Olivia HandayaniUniversity of Brawijaya1
Dadang HendrawanUniversity of Brawijaya1
Anita Surya SantosoUniversity of Brawijaya1
Salvatore Di SommaSapienza University of Rome1
Krishna Ari NugrahaUniversity of Brawijaya1
Ayu Asri Devi AdityawatiUniversity of Brawijaya1
Imelda KrisnasariUniversity of Brawijaya1
Akhmad Isna NurudinullohUniversity of Brawijaya1
Arief WibisonoAfiliasi tidak diketahui1
Bayu Purnomo AjiUniversity of Brawijaya1
Krishna Ari NugrahaAfiliasi tidak diketahui1
Seprian WidasmaraUniversity of Brawijaya1

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Sumber metadata: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Left Ventricular Hypertrophy and Clinical Outcomes in Heart Failure Patients Based on Hypertension Subtypes: Insights from a Tertiary Hospital Heart Failure Registry in Malang, Indonesia</dc:title>
	<dc:creator xml:lang="en">Satrijo, Budi</dc:creator>
	<dc:creator xml:lang="en">Maharani, Andona Murni</dc:creator>
	<dc:creator xml:lang="en">Fadlan, Muhammad Rizki</dc:creator>
	<dc:creator xml:lang="en">Suryo Baskoro, Shalahuddin</dc:creator>
	<dc:subject xml:lang="en">Isolated Systolic Hypertension</dc:subject>
	<dc:subject xml:lang="en">Left Ventricular Hypertrophy</dc:subject>
	<dc:subject xml:lang="en">Heart Failure</dc:subject>
	<dc:description xml:lang="en">BackgroundLeft ventricular hypertrophy (LVH) is a maladaptive response to chronic pressure overload and an important risk factor sudden death in patients with heart failure. Previous studies show that LVH is a risk factor for systolic heart failure. It’s interesting to examine whether Isolated Systolic Hypertension (ISH) in the presence of LVH contribute to clinical outcome.Objective: The aims of this study to examined association of  ISH with cardiovascular outcomes and to examined associations of ISH and LVH  in Heart failure registry patientMethods: A total of 120 subject’s were collected from Saiful Anwar Heart Failure Registry from January 2019 to December 2019. All participants were individually interviewed with a structured questionnaire  for collecting baseline characteristic. Subject were classified into 2 group of hypertension (ISH and Systolic Diastolic Hypertension (SDH)). ISH based on the criteria of SBP ≥ 140 and DBP &amp;lt; 90 mmHg and SDH based on SBP ≥ 140 and DBP ≥ 90 mmHg. The EF and volumes were measured with 2D-biplane Simpson's method by measured as a standart mannerResult’s: ISH commonly found among older hypertensive patients than SDH (Mean age 61,23±11,2 yo  vs  53,52±11,1 yo, respectively, p&amp;lt;0,04)). LVH was more prevalence among ISH  than SDH. No difference in clinical outcome such as in hospital mortality, Rehospitalization, and Lengt of stay were observed in both groups. Complication of hypertension was similar in both groups such as stroke, Myocardial Infarct, and Chronic Kidney Disease. Intrestingly, no difference also observe in compliance to the drug between ISH and SDH. We also examined subgroup analysis of subject’s with ISH. There was no statistically significant difference in clinical outcome between ISH with LVH and ISH without LVH.Conclusion: In this study, we suggest that ISH more common in older patient with HF than SDH  but had similar associations with cardiovascular mortality and rehospitalization. ISH was associated with a higher prevalence of left ventricular hypertrophy than SDH.</dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2023-04-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/1387</dc:identifier>
	<dc:identifier>10.21776/ub.hsj.2023.004.02.4</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 4 No. 2 (2023): Dealing with the Complexity of the Wide Spectrum of Cardiovascular Disease; 18-22</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2023.004.02</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/1387/228</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2023 Budi Satrijo, Andona Murni Maharani, Muhammad Rizki Fadlan, Shalahuddin Suryo Baskoro</dc:rights>
</oai_dc:dc>