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Cardiac implantable electronic device infection - how to recognize and treat?

Heart Science Journal · Vol. 6 No. 3 (2025)

DOI
10.21776/ub.hsj.2025.006.03.10
ISSN
2721-9984, 2721-9976
Terbit
2025-07-31
Penerbit
Universitas Brawijaya
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Implantable Electronic Devices (CIEDs) have significantly transformed the treatment of various heart conditions. However, their growing use has been accompanied by an increase in device-related infections, posing a serious medical concern. Early identification of CIED infections is essential for prompt and effective treatment. Typical clinical signs include localized infection symptoms—such as redness, warmth, and tenderness around the implant site—as well as general symptoms like fever and fatigue. Diagnostic support also comes from laboratory tests, particularly elevated inflammatory markers. Management of these infections requires a coordinated, multidisciplinary approach. Timely removal of the infected device is critical, along with the administration of targeted antibiotics based on culture and sensitivity findings. In some instances, surgical removal of the entire device, including any leads, may be necessary. Preventing such infections is equally important and involves strict adherence to aseptic techniques during implantation and any subsequent procedures. Prophylactic antibiotics may also be warranted for patients at high risk. In summary, the successful management of CIED infections relies on early detection, accurate diagnosis, and a well-coordinated treatment plan. Preventive measures are vital in decreasing infection rates and ensuring the best possible outcomes for patients.

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  • University of Brawijaya
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Rekan penulisOrganisasiArtikel bersama
Mohammad Saifur RohmanUniversity of Brawijaya19
Anna Fuji RahimahUniversity of Brawijaya12
Indra PrasetyaUniversity of Brawijaya11
Sasmojo WiditoUniversity of Brawijaya9
Novi KurnianingsihUniversity of Brawijaya9
Setyasih AnjarwaniUniversity of Brawijaya9
Heny MartiniUniversity of Brawijaya7
Djanggan SargowoUniversity of Brawijaya4
Cholid Tri TjahjonoUniversity of Brawijaya4
Adhika Prastya WikanandaUniversity of Brawijaya4
Wella KarolinaUniversity of Brawijaya4
Yoga WaranugrahaUniversity of Brawijaya3
Budi SatrijoUniversity of Brawijaya3
Valerinna Yogibuana Swastika PutriUniversity of Brawijaya3
Puspa LestariUniversity of Brawijaya2
Olivia HandayaniUniversity of Brawijaya2
Fahmy RusnantaUniversity of Brawijaya2
Anita Surya SantosoAfiliasi tidak diketahui2
Fitranti Suciati LaitupaUniversity of Brawijaya2
Muhammad Saifur RohmanAfiliasi tidak diketahui2
Valerinna YogibuanaAfiliasi tidak diketahui2
Tri AstiawatiUniversity of Brawijaya2
N KaputrinUniversity of Brawijaya2
Nikhen NoverikeUniversity of Brawijaya2
Gebryel Dennis SaerangUniversity of Brawijaya2
Vemmy Lian SaputriUniversity of Brawijaya2
Cik KahadiUniversity of Brawijaya2
Putri Annisa KamilaUniversity of Brawijaya1
Djanggan SargowoAfiliasi tidak diketahui1
Jonny Karunia FajarUniversity of Brawijaya1
Aditha Satria MaulanaUniversity of Brawijaya1
Aris Munandar Zulkifli IsmailUniversity of Brawijaya1
Anna Fuji RahimahAfiliasi tidak diketahui1
Aris Munandar ZIAfiliasi tidak diketahui1
Tonny AdriyantoUniversity of Brawijaya1
Seprian WidasmaraUniversity of Brawijaya1
Heny MartiniAfiliasi tidak diketahui1
Faris Wahyu NugrohoUniversity of Brawijaya1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Cardiac implantable electronic device infection - how to recognize and treat?</dc:title>
	<dc:creator xml:lang="en">Rochmawati, Icmi Dian</dc:creator>
	<dc:creator xml:lang="en">Rizal, Ardian</dc:creator>
	<dc:subject xml:lang="en">Cardiac Implantable Electronic Devices</dc:subject>
	<dc:subject xml:lang="en">infections</dc:subject>
	<dc:subject xml:lang="en">Preventive Measures</dc:subject>
	<dc:description xml:lang="en">Implantable Electronic Devices (CIEDs) have significantly transformed the treatment of various heart conditions. However, their growing use has been accompanied by an increase in device-related infections, posing a serious medical concern. Early identification of CIED infections is essential for prompt and effective treatment. Typical clinical signs include localized infection symptoms—such as redness, warmth, and tenderness around the implant site—as well as general symptoms like fever and fatigue. Diagnostic support also comes from laboratory tests, particularly elevated inflammatory markers. Management of these infections requires a coordinated, multidisciplinary approach. Timely removal of the infected device is critical, along with the administration of targeted antibiotics based on culture and sensitivity findings. In some instances, surgical removal of the entire device, including any leads, may be necessary. Preventing such infections is equally important and involves strict adherence to aseptic techniques during implantation and any subsequent procedures. Prophylactic antibiotics may also be warranted for patients at high risk. In summary, the successful management of CIED infections relies on early detection, accurate diagnosis, and a well-coordinated treatment plan. Preventive measures are vital in decreasing infection rates and ensuring the best possible outcomes for patients.</dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2025-07-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/15725</dc:identifier>
	<dc:identifier>10.21776/ub.hsj.2025.006.03.10</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visualization</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2025.006.03</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/15725/526</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 Icmi Dian Rochmawati, Ardian Rizal</dc:rights>
	<dc:rights xml:lang="en">http://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>