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Neutrophil-Lymphocyte Ratio (NLR) as A Predictor for Non-ST Elevation Myocardial Infarction (NSTEMI) in the Emergency Room

Heart Science Journal · Vol. 5 No. 3 (2024) · hlm. 39–44

DOI
10.21776/ub/hsj.2024.005.03.7
ISSN
2721-9984, 2721-9976
Terbit
2024-07-30
Penerbit
Universitas Brawijaya
Bahasa
en

Abstrak

AbstractBackground: The usefulness of the NLR as an approach to identifying cases of acute coronary syndrome (ACS) needs to be improved.Objective: This research was designed to determine the effectiveness of the NLR in identifying individuals who presented to the emergency room complaining of anginal due to ACS.Methods: The single-center cross-sectional study was performed at Saiful Anwar General Hospital in Malang, East Java, Indonesia, from July 2020 to December 2023. Patients were involved in this study with complaints of angina suspected of ACS. During further observation in the emergency room, based on the findings of the troponin I analysis, individuals were divided into unstable angina pectoris (UAP) and NSTEMI.Results: Study results were collected from 282 individuals diagnosed with Non-ST Elevation Acute Coronary Syndrome (NSTEACS), with 75.9% male and a mean age of 58.39 ± 10.27 years. The NLR threshold was 4.5 (AUC: 0.78, 95% CI: 0.765–0.867, P <.001) assessed during admission, which showed a sensitivity of 79% and a specificity of 78% in accurately predicting the probability of subsequent troponin positivity. Multivariate analysis revealed that the NLR at hospitalization remained an essential marker of troponin positivity during follow-up.Conclusions: In the end, NLR could be considered an initial test in emergency services to predict the diagnosis of NSTEMI in people experiencing angina.Â

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Mohammad Saifur RohmanAfiliasi tidak diketahui69
Ardian RizalAfiliasi tidak diketahui37
Cholid Tri TjahjonoAfiliasi tidak diketahui30
Djanggan SargowoAfiliasi tidak diketahui25
Novi KurnianingsihAfiliasi tidak diketahui25
Heny MartiniAfiliasi tidak diketahui23
Sasmojo WiditoAfiliasi tidak diketahui18
Wella KarolinaAfiliasi tidak diketahui11
Valerinna YogibuanaAfiliasi tidak diketahui11
Muhammad Rizki FadlanAfiliasi tidak diketahui7
Nikhen NoverikeAfiliasi tidak diketahui6
Imelda KrisnasariAfiliasi tidak diketahui6
Putri Annisa KamilaUniversity of Brawijaya6
Yoga WaranugrahaAfiliasi tidak diketahui5
Dea Arie KurniawanAfiliasi tidak diketahui5
Ayu Asri Devi AdityawatiAfiliasi tidak diketahui5
Valerinna Yogibuana Swastika PutriAfiliasi tidak diketahui5
Teguh AryanugrahaAfiliasi tidak diketahui5
Yuri AfifahAfiliasi tidak diketahui5
Hayla Iqda MillisaniAfiliasi tidak diketahui4
Lukitasari Ayu GaluhAfiliasi tidak diketahui4
Yoseph Budi UtomoAfiliasi tidak diketahui4
Anita Surya SantosoAfiliasi tidak diketahui4
Krishna Ari NugrahaAfiliasi tidak diketahui4
Seprian WidasmaraAfiliasi tidak diketahui4
Tri AstiawatiAfiliasi tidak diketahui4
Saskia Dyah HandariAfiliasi tidak diketahui4
Danti Utami SetyowatiAfiliasi tidak diketahui3
Muhammad Saifur RohmanAfiliasi tidak diketahui3
Olivia HandayaniAfiliasi tidak diketahui3
Fahmy RusnantaAfiliasi tidak diketahui3
Oktafin Srywati PamunaAfiliasi tidak diketahui3
Imam Mi'raj SuprayogaAfiliasi tidak diketahui3
Veny KurniawatiAfiliasi tidak diketahui2
Cholid Tri TjahjonoAfiliasi tidak diketahui2

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Sumber metadata: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Neutrophil-Lymphocyte Ratio (NLR) as A Predictor for Non-ST Elevation Myocardial Infarction (NSTEMI) in the Emergency Room</dc:title>
	<dc:creator xml:lang="en">Zunardi, Lutfi Hafiz</dc:creator>
	<dc:creator xml:lang="en">Anjarwani, Setyasih</dc:creator>
	<dc:creator xml:lang="en">Prasetya, Indra</dc:creator>
	<dc:creator xml:lang="en">Satrijo, Budi</dc:creator>
	<dc:creator xml:lang="en">Rahimah, Anna Fuji</dc:creator>
	<dc:subject xml:lang="en">Marker Inflammation</dc:subject>
	<dc:subject xml:lang="en">NLR</dc:subject>
	<dc:subject xml:lang="en">NSTEMI</dc:subject>
	<dc:subject xml:lang="en">Troponin I.</dc:subject>
	<dc:description xml:lang="en">AbstractBackground: The usefulness of the NLR as an approach to identifying cases of acute coronary syndrome (ACS) needs to be improved.Objective: This research was designed to determine the effectiveness of the NLR in identifying individuals who presented to the emergency room complaining of anginal due to ACS.Methods: The single-center cross-sectional study was performed at Saiful Anwar General Hospital in Malang, East Java, Indonesia, from July 2020 to December 2023. Patients were involved in this study with complaints of angina suspected of ACS. During further observation in the emergency room, based on the findings of the troponin I analysis, individuals were divided into unstable angina pectoris (UAP) and NSTEMI.Results: Study results were collected from 282 individuals diagnosed with Non-ST Elevation Acute Coronary Syndrome (NSTEACS), with 75.9% male and a mean age of 58.39 ± 10.27 years. The NLR threshold was 4.5 (AUC: 0.78, 95% CI: 0.765–0.867, P &amp;lt;.001) assessed during admission, which showed a sensitivity of 79% and a specificity of 78% in accurately predicting the probability of subsequent troponin positivity. Multivariate analysis revealed that the NLR at hospitalization remained an essential marker of troponin positivity during follow-up.Conclusions: In the end, NLR could be considered an initial test in emergency services to predict the diagnosis of NSTEMI in people experiencing angina. </dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2024-07-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/15759</dc:identifier>
	<dc:identifier>10.21776/ub/hsj.2024.005.03.7</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 5 No. 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome; 39-44</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2024.005.03</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/15759/423</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Lutfi hafiz zunardi</dc:rights>
</oai_dc:dc>