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Impact of clinical features on in-hospital outcomes in premature coronary artery disease patients post percutaneous coronary intervention

Heart Science Journal · Vol. 5 No. 4 (2024) · hlm. 65–70

DOI
10.21776/ub.hsj.2024.005.04.11
ISSN
2721-9984, 2721-9976
Terbit
2024-10-28
Penerbit
Universitas Brawijaya
Bahasa
en

Abstrak

Background: Premature coronary artery disease (PCAD) is a significant health concern globally, characterized by the onset of coronary atherosclerosis at an early age. The development of PCAD is influenced by a variety of risk factors and leading to substantial morbidity and mortality. Despite advancements in interventions, the clinical and angiographic characteristics influencing in-hospital outcomes for these patients remain underexplored.Objective: This study aims to investigate the relationship between clinical features and in-hospital outcomes in patients with premature CAD post-percutaneous coronary intervention (PCI) at Dr. Saiful Anwar Hospital.Method: A retrospective cohort study was conducted on 1279 patients who underwent PCI for premature CAD from January 2022 to December 2023. Clinical data, including risk factors and angiographic findings, were collected from medical records. Statistical analyses were conducted using SPSS 22, employing univariate, bivariate, and multivariate logistic regression analyses to determine correlations.Result: The study included 1279 patients, with 438 in the premature CAD group and 841 in the non-premature CAD group. Significant differences were observed in age, sex distribution, BMI, lipid profiles, smoking status, and family history between the groups. Premature CAD patients were younger (mean age 50 vs. 64.8, p<0.001) and had higher rates of smoking and dyslipidemia. Angiographic analysis showed significant differences in LAD and LCx involvement and occlusion rates. In-hospital outcomes indicated higher incidences of shock, cardiac complications, and in-hospital mortality in the non-premature CAD group.Conclusion: Clinical and angiographic characteristics significantly influence in-hospital outcomes for premature CAD patients. Younger age, smoking, and dyslipidemia were prevalent risk factors. Enhanced management strategies focusing on these factors could improve patient outcomes.Keywords: Premature coronary artery disease, percutaneous coronary intervention, clinical characteristics, angiographic findings, in-hospital outcomes.Â

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  • University of Brawijaya
  • RSUD Prof. Dr. Saiful Anwar Malang
  • Afiliasi tidak diketahui
  • Organisasi berbeda
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Rekan penulisOrganisasiArtikel bersama
Setyasih AnjarwaniUniversity of Brawijaya49
Novi KurnianingsihUniversity of Brawijaya38
Cholid Tri TjahjonoUniversity of Brawijaya37
Budi SatrijoUniversity of Brawijaya34
Heny MartiniUniversity of Brawijaya33
Djanggan SargowoUniversity of Brawijaya25
Sasmojo WiditoUniversity of Brawijaya25
Wella KarolinaUniversity of Brawijaya18
Yoga WaranugrahaUniversity of Brawijaya14
Valerinna YogibuanaAfiliasi tidak diketahui12
Adhika Prastya WikanandaUniversity of Brawijaya9
Tri AstiawatiUniversity of Brawijaya9
Putri Annisa KamilaUniversity of Brawijaya7
Muhammad Rizki FadlanUniversity of Brawijaya7
Hayla Iqda MillisaniUniversity of Brawijaya6
Icmi Dian RochmawatiUniversity of Brawijaya6
Fahmy RusnantaUniversity of Brawijaya6
Ratna PancasariUniversity of Brawijaya6
Seprian WidasmaraUniversity of Brawijaya6
Valerinna Yogibuana Swastika PutriUniversity of Brawijaya6
Tria Yudha NugrahaUniversity of Brawijaya5
Fandy HazzyUniversity of Brawijaya5
Danti Utami SetyowatiRSUD Prof. Dr. Saiful Anwar Malang5
Olivia HandayaniUniversity of Brawijaya5
Ayu Asri Devi AdityawatiUniversity of Brawijaya5
Imelda KrisnasariUniversity of Brawijaya5
N KaputrinUniversity of Brawijaya5
Lukitasari Ayu Galuh ArdhiUniversity of Brawijaya4
Oktafin Srywati PamunaUniversity of Brawijaya4
Anna Fuji RahimahAfiliasi tidak diketahui4
Lutfi Hafiz ZunardiUniversity of Brawijaya4
Teguh AryanugrahaUniversity of Brawijaya4
Mokhamad Aswin BaharUniversity of Brawijaya4
Dea Arie KurniawanUniversity of Brawijaya4
Dadang HendrawanUniversity of Brawijaya3

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc)
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Impact of clinical features on in-hospital outcomes in premature coronary artery disease patients post percutaneous coronary intervention</dc:title>
	<dc:creator xml:lang="en">Noverike, Nikhen</dc:creator>
	<dc:creator xml:lang="en">Rohman, Mohammad Saifur</dc:creator>
	<dc:creator xml:lang="en">Rahimah, Anna Fuji</dc:creator>
	<dc:creator xml:lang="en">Rizal, Ardian</dc:creator>
	<dc:creator xml:lang="en">Prasetya, Indra</dc:creator>
	<dc:description xml:lang="en">Background: Premature coronary artery disease (PCAD) is a significant health concern globally, characterized by the onset of coronary atherosclerosis at an early age. The development of PCAD is influenced by a variety of risk factors and leading to substantial morbidity and mortality. Despite advancements in interventions, the clinical and angiographic characteristics influencing in-hospital outcomes for these patients remain underexplored.Objective: This study aims to investigate the relationship between clinical features and in-hospital outcomes in patients with premature CAD post-percutaneous coronary intervention (PCI) at Dr. Saiful Anwar Hospital.Method: A retrospective cohort study was conducted on 1279 patients who underwent PCI for premature CAD from January 2022 to December 2023. Clinical data, including risk factors and angiographic findings, were collected from medical records. Statistical analyses were conducted using SPSS 22, employing univariate, bivariate, and multivariate logistic regression analyses to determine correlations.Result: The study included 1279 patients, with 438 in the premature CAD group and 841 in the non-premature CAD group. Significant differences were observed in age, sex distribution, BMI, lipid profiles, smoking status, and family history between the groups. Premature CAD patients were younger (mean age 50 vs. 64.8, p&amp;lt;0.001) and had higher rates of smoking and dyslipidemia. Angiographic analysis showed significant differences in LAD and LCx involvement and occlusion rates. In-hospital outcomes indicated higher incidences of shock, cardiac complications, and in-hospital mortality in the non-premature CAD group.Conclusion: Clinical and angiographic characteristics significantly influence in-hospital outcomes for premature CAD patients. Younger age, smoking, and dyslipidemia were prevalent risk factors. Enhanced management strategies focusing on these factors could improve patient outcomes.Keywords: Premature coronary artery disease, percutaneous coronary intervention, clinical characteristics, angiographic findings, in-hospital outcomes. </dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2024-10-28</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/20129</dc:identifier>
	<dc:identifier>10.21776/ub.hsj.2024.005.04.11</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 5 No. 4 (2024): The Current Perspective About Cardiometabolic Disease; 65-70</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2024.005.04</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/20129/441</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2024 Nikhen Noverike</dc:rights>
</oai_dc:dc>