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Unveiling strategies in acute cardiac care for ventricular septal rupture following acute myocardial infarction: Lessons from cases

Heart Science Journal · Vol. 6 No. 2 (2025)

DOI
10.21776/ub.hsj.2025.006.02.17
ISSN
2721-9984, 2721-9976
Terbit
2025-04-30
Penerbit
Universitas Brawijaya
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Background: Ventricular septal rupture (VSR) following acute myocardial infarction (AMI) is drastically decreasing in the reperfusion era but mortality remains high. VSR correction is the definitive treatment and using mechanical support to delay closure is an attractive option despite data on success being limited. Case Illustration: A 60-year-old man presented with late presentation of anterior STEMI complicating hemodynamic deterioration. Echocardiography showed apical VSR 11-14 mm L-R shunt. Patient was given adequate fluids, multiple inotropic agents, and IABP insertion, then a successful PPCI procedure was performed immediately. IABP was maintained for hemodynamic stabilization and patient was scheduled for interventional closure. Unfortunately, the patient worsened due to cardiogenic shock and passed away on the 5th day of admission. In another case, a 61-year-old man came to our hospital also with a late presentation of anterior STEMI but stable in hemodynamics. Echocardiography showed apical VSR 9-11 mm L-R shunt. Coronary angiography showed CAD three vessel disease with critical stenosis at LAD. In hospital’s heart team discussion, patient was planned to be performed VSR closure percutaneously and continue with PCI procedure. Both procedures were performed successfully. Patient was improved and discharged on 20th day of admission. Conclusion: Rapid diagnosis and prompt treatment are the keys to optimal management of VSR complicating late presentation STEMI. Mechanical circulatory support and correction of VSR are required to optimize patient outcomes despite VSR is still a challenging case.

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  • University of Brawijaya
  • RSUD Prof. Dr. Saiful Anwar Malang
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Rekan penulisOrganisasiArtikel bersama
Mohammad Saifur RohmanUniversity of Brawijaya56
Ardian RizalUniversity of Brawijaya36
Cholid Tri TjahjonoUniversity of Brawijaya28
Heny MartiniUniversity of Brawijaya26
Budi SatrijoUniversity of Brawijaya23
Novi KurnianingsihUniversity of Brawijaya19
Djanggan SargowoUniversity of Brawijaya18
Sasmojo WiditoUniversity of Brawijaya12
Nikhen NoverikeUniversity of Brawijaya7
Muhammad Rizki FadlanUniversity of Brawijaya7
Tria Yudha NugrahaUniversity of Brawijaya6
Valerinna Yogibuana Swastika PutriUniversity of Brawijaya6
Hayla Iqda MillisaniUniversity of Brawijaya4
Danti Utami SetyowatiRSUD Prof. Dr. Saiful Anwar Malang4
Putri Annisa KamilaUniversity of Brawijaya4
Yoga WaranugrahaUniversity of Brawijaya4
Ayu Asri Devi AdityawatiUniversity of Brawijaya4
Tri AstiawatiUniversity of Brawijaya4
Dion SetiawanUniversity of Brawijaya4
N KaputrinUniversity of Brawijaya4
Teguh AryanugrahaUniversity of Brawijaya4
Dea Arie KurniawanUniversity of Brawijaya4
Lukitasari Ayu Galuh ArdhiUniversity of Brawijaya3
Yoseph Budi UtomoUniversity of Brawijaya3
Ratna PancasariUniversity of Brawijaya3
Krishna Ari NugrahaUniversity of Brawijaya3
Seprian WidasmaraUniversity of Brawijaya3
Ardian RizalUniversity of Brawijaya3
Fahmy RusnantaUniversity of Brawijaya3
Oktafin Srywati PamunaUniversity of Brawijaya3
Saskia Dyah HandariUniversity of Brawijaya3
Veny KurniawatiUniversity of Brawijaya2
Olivia HandayaniUniversity of Brawijaya2
Liemena Harold AdrianRSUD Prof. Dr. Saiful Anwar Malang2

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Sumber metadata: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc)
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Unveiling strategies in acute cardiac care for ventricular septal rupture following acute myocardial infarction: Lessons from cases</dc:title>
	<dc:creator xml:lang="en">Nurudinulloh, Akhmad Isna</dc:creator>
	<dc:creator xml:lang="en">Anjarwani, Setyasih</dc:creator>
	<dc:creator xml:lang="en">Prasetya, Indra</dc:creator>
	<dc:creator xml:lang="en">Yogibuana, Valerinna</dc:creator>
	<dc:creator xml:lang="en">Rahimah, Anna Fuji</dc:creator>
	<dc:creator xml:lang="en">Karolina, Wella</dc:creator>
	<dc:subject xml:lang="en">ventricular septal rupture</dc:subject>
	<dc:subject xml:lang="en">acute cardiac care</dc:subject>
	<dc:subject xml:lang="en">IABP</dc:subject>
	<dc:subject xml:lang="en">percutaneous VSR closure</dc:subject>
	<dc:description xml:lang="en">Background: Ventricular septal rupture (VSR) following acute myocardial infarction (AMI) is drastically decreasing in the reperfusion era but mortality remains high. VSR correction is the definitive treatment and using mechanical support to delay closure is an attractive option despite data on success being limited.
Case Illustration: A 60-year-old man presented with late presentation of anterior STEMI complicating hemodynamic deterioration. Echocardiography showed apical VSR 11-14 mm L-R shunt. Patient was given adequate fluids, multiple inotropic agents, and IABP insertion, then a successful PPCI procedure was performed immediately. IABP was maintained for hemodynamic stabilization and patient was scheduled for interventional closure. Unfortunately, the patient worsened due to cardiogenic shock and passed away on the 5th day of admission.
In another case, a 61-year-old man came to our hospital also with a late presentation of anterior STEMI but stable in hemodynamics. Echocardiography showed apical VSR 9-11 mm L-R shunt. Coronary angiography showed CAD three vessel disease with critical stenosis at LAD. In hospital’s heart team discussion, patient was planned to be performed VSR closure percutaneously and continue with PCI procedure. Both procedures were performed successfully. Patient was improved and discharged on 20th day of admission.
Conclusion: Rapid diagnosis and prompt treatment are the keys to optimal management of VSR complicating late presentation STEMI. Mechanical circulatory support and correction of VSR are required to optimize patient outcomes despite VSR is still a challenging case.</dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2025-04-30</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/20171</dc:identifier>
	<dc:identifier>10.21776/ub.hsj.2025.006.02.17</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 6 No. 2 (2025): The Complexity in the Management of Heart Rhythm Disorder</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2025.006.02</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/20171/500</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 Akhmad Isna Nurudinulloh, Setyasih Anjarwani, Indra Prasetya, Valerinna Yogibuana, Anna Fuji Rahimah, Wella Karolina</dc:rights>
	<dc:rights xml:lang="en">http://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>