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Factors that influence the clinical and technical success of venoplasty in patients with central venous stenosis at Saiful Anwar hospital

Heart Science Journal · Vol. 6 No. 4 (2025)

DOI
10.21776/ub.hsj.2025.006.04.8
ISSN
2721-9984, 2721-9976
Terbit
2025-10-31
Penerbit
Universitas Brawijaya
Bahasa
en
Lisensi
creativecommons.org/licenses/by/4.0

Abstrak

Background: Central venous stenosis (CVS) is a common complication in long-term hemodialysis patients, particularly those with a history of central venous catheterization. Percutaneous transluminal venoplasty is the primary treatment modality; however, its success varies depending on anatomical and procedural factors. Objectives: This study aimed to evaluate the procedural success of venoplasty in CVS patients and to identify anatomical and procedural factors associated with wire-crossing failure and residual stenosis of less than 30%. Materials and Methods: A retrospective study was conducted involving 55 patients with CVS who underwent venoplasty at Dr. Saiful Anwar General Hospital, Malang, between 2021 and 2025. Data collected included patient demographics, lesion characteristics, and procedural variables. Data were analyzed using SPSS version 27. Descriptive statistics were used to summarize baseline characteristics. Chi-square or Fisher’s exact tests were used for bivariate analysis, followed by multivariate logistic regression to determine independent predictors of procedural success. Results: Wire crossing was successfully achieved in 76.4% of cases, while balloon venoplasty resulted in residual stenosis <30% in 74.5% of patients. Multivariate analysis revealed that total occlusion (OR 1.619; 95% CI: 1.243–2.109; p = 0.001), presence of venous collaterals (OR 1.429; 95% CI: 0.974–2.094; p = 0.048), and vessel tortuosity (OR 2.237; 95% CI: 1.258–3.978; p = 0.000) were significantly associated with wire-crossing failure. Clinical success (residual stenosis <30%) was significantly associated with non-total occlusion (OR 1.542; 95% CI: 1.164–2.043; p = 0.014) and absence of vessel tortuosity (OR 2.610; 95% CI: 1.362–5.001; p = 0.000). No significant associations were found between procedural outcomes and factors such as wire type, balloon pressure, or puncture technique. Conclusion: Anatomical characteristics—including total occlusion, vessel tortuosity, and collateral formation—are the key determinants of venoplasty success in patients with CVS, outweighing the influence of procedural variables. Comprehensive anatomical assessment prior to intervention is essential to optimize procedural outcomes.

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Cholid Tri TjahjonoAfiliasi tidak diketahui12
Mohammad Saifur RohmanAfiliasi tidak diketahui12
Sasmojo WiditoAfiliasi tidak diketahui11
Ardian RizalAfiliasi tidak diketahui10
Anna Fuji RahimahAfiliasi tidak diketahui10
Djanggan SargowoAfiliasi tidak diketahui9
Heny MartiniAfiliasi tidak diketahui6
Budi SatrijoAfiliasi tidak diketahui6
Indra PrasetyaAfiliasi tidak diketahui6
Seprian WidasmaraAfiliasi tidak diketahui3
Adhika Prastya WikanandaAfiliasi tidak diketahui3
Sawitri SatwikajatiAfiliasi tidak diketahui3
Setyasih AnjarwaniAfiliasi tidak diketahui3
Putri Annisa KamilaUniversity of Brawijaya2
Irma KameliaAfiliasi tidak diketahui2
Dyah Ayu IkeningrumAfiliasi tidak diketahui2
Oktafin Srywati PamunaAfiliasi tidak diketahui2
Zainal FathurohimAfiliasi tidak diketahui2
Nikhen NoverikeAfiliasi tidak diketahui2
Titin Andri WihastutiAfiliasi tidak diketahui2
Imam Mi'raj SuprayogaAfiliasi tidak diketahui2
Dea Arie KurniawanAfiliasi tidak diketahui2
Malombassi Dharmawan Hadiwidjojo HutomoAfiliasi tidak diketahui2
Mohammad Ryan RamadhanAfiliasi tidak diketahui1
Veny KurniawatiAfiliasi tidak diketahui1
Aris Munandar Zulkifli IsmailAfiliasi tidak diketahui1
Dedy IrawanAfiliasi tidak diketahui1
Monika SitioAfiliasi tidak diketahui1
Muhammad Rizki FadlanAfiliasi tidak diketahui1
Liemena Harold AdrianAfiliasi tidak diketahui1
Ayu Asri Devi AdityawatiAfiliasi tidak diketahui1
Imelda KrisnasariAfiliasi tidak diketahui1
Fahmy RusnantaAfiliasi tidak diketahui1
Yudi Putra ApridityaAfiliasi tidak diketahui1
Ratna PancasariAfiliasi tidak diketahui1
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Sumber metadata: OAI-PMH (metadata jurnal) https://heartscience.ub.ac.id/index.php/heartscience/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en">Factors that influence the clinical and technical success of venoplasty in patients with central venous stenosis at Saiful Anwar hospital</dc:title>
	<dc:creator xml:lang="en">Kurnianingsih, Novi</dc:creator>
	<dc:creator xml:lang="en">Akbar, Akita Rukmana</dc:creator>
	<dc:subject xml:lang="en">Central Venous Stenosis</dc:subject>
	<dc:subject xml:lang="en">Hemodialysis</dc:subject>
	<dc:subject xml:lang="en">Technical Success</dc:subject>
	<dc:subject xml:lang="en">Vascular Tortuosity</dc:subject>
	<dc:subject xml:lang="en">Venoplasty</dc:subject>
	<dc:description xml:lang="en">Background: Central venous stenosis (CVS) is a common complication in long-term hemodialysis patients, particularly those with a history of central venous catheterization. Percutaneous transluminal venoplasty is the primary treatment modality; however, its success varies depending on anatomical and procedural factors.
Objectives: This study aimed to evaluate the procedural success of venoplasty in CVS patients and to identify anatomical and procedural factors associated with wire-crossing failure and residual stenosis of less than 30%.
Materials and Methods: A retrospective study was conducted involving 55 patients with CVS who underwent venoplasty at Dr. Saiful Anwar General Hospital, Malang, between 2021 and 2025. Data collected included patient demographics, lesion characteristics, and procedural variables. Data were analyzed using SPSS version 27. Descriptive statistics were used to summarize baseline characteristics. Chi-square or Fisher’s exact tests were used for bivariate analysis, followed by multivariate logistic regression to determine independent predictors of procedural success.
Results: Wire crossing was successfully achieved in 76.4% of cases, while balloon venoplasty resulted in residual stenosis &amp;lt;30% in 74.5% of patients. Multivariate analysis revealed that total occlusion (OR 1.619; 95% CI: 1.243–2.109; p = 0.001), presence of venous collaterals (OR 1.429; 95% CI: 0.974–2.094; p = 0.048), and vessel tortuosity (OR 2.237; 95% CI: 1.258–3.978; p = 0.000) were significantly associated with wire-crossing failure. Clinical success (residual stenosis &amp;lt;30%) was significantly associated with non-total occlusion (OR 1.542; 95% CI: 1.164–2.043; p = 0.014) and absence of vessel tortuosity (OR 2.610; 95% CI: 1.362–5.001; p = 0.000). No significant associations were found between procedural outcomes and factors such as wire type, balloon pressure, or puncture technique.
Conclusion: Anatomical characteristics—including total occlusion, vessel tortuosity, and collateral formation—are the key determinants of venoplasty success in patients with CVS, outweighing the influence of procedural variables. Comprehensive anatomical assessment prior to intervention is essential to optimize procedural outcomes.</dc:description>
	<dc:publisher xml:lang="en">Universitas Brawijaya</dc:publisher>
	<dc:date>2025-10-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://heartscience.ub.ac.id/index.php/heartscience/article/view/20476</dc:identifier>
	<dc:identifier>10.21776/ub.hsj.2025.006.04.8</dc:identifier>
	<dc:source xml:lang="en">Heart Science Journal; Vol. 6 No. 4 (2025): The Pursuit of Precision: Navigating Risks, Refining Diagnosis, and Securing Long-Term Vascular Outcomes in Contemporary Cardiovascular Practice</dc:source>
	<dc:source>2721-9984</dc:source>
	<dc:source>2721-9976</dc:source>
	<dc:source>10.21776/ub.hsj.2025.006.04</dc:source>
	<dc:language>en</dc:language>
	<dc:relation>https://heartscience.ub.ac.id/index.php/heartscience/article/view/20476/538</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 Novi Kurnianingsih, Akita Rukmana Akbar</dc:rights>
	<dc:rights xml:lang="en">http://creativecommons.org/licenses/by/4.0</dc:rights>
</oai_dc:dc>