Melola Discovery

← Melola Discovery

Jurnal SINTA 1

Cytotoxic Effects of Cinnamon Powder and Lemongrass Oil-Enriched Roselle Tea on T47D Breast Cancer Cells

Indonesian Journal of Cancer Chemoprevention · Vol. 15 No. 3 (2024) · hlm. 186–197

DOI
10.14499/indonesianjcanchemoprev15iss3pp186-197
ISSN
2355-8989, 2088-0197
Terbit
2024-10-31
Penerbit
Indonesian Society for Cancer Chemoprevention
Bahasa
eng

Abstrak

Breast cancer is the most prevalent cancer among women and is the leading cause of cancer-related mortality worldwide. This underlines the importance of preventive strategies to reduce the risk. Harnessing natural products like tea could be an alternative preventive strategy. In this study, the chemopreventive potential of roselle flower tea (Hibiscus sabdariffa L.) enriched with cinnamon oil (Cinnamomum burmannii) and lemongrass (Cymbopogon citratus) was evaluated. The tea was formulated using a stirred boiler tank and tested for its cytotoxicity against T47D cells using the MTT method. The cytotoxicity test showed that with the addition of cinnamon oil and lemongrass, roselle tea had more significant cytotoxic activity against T47D cancer cells than pristine roselle tea. Adding 5 g of cinnamon and lemongrass oil vapor for 15 seconds into the tea showed the highest cytotoxicity, with an IC50 of 730 μg/mL. This value is almost three times higher than without adding cinnamon oil and lemongrass. In conclusion, adding cinnamon oil and lemongrass to the roselle tea formulation can increase cytotoxic activity against T47D cancer cells, indicating its potential as a natural anti-cancer agent.Keywords: Chemopreventive, Cinnamon, Lemongrass, Roselle Tea, T47D Cells.

Jaringan kolaborasi para penulis

40 penulis · 111 tautan kepenulisan bersama · 21 lintas organisasi · menampilkan 40 yang paling banyak terhubung

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

  • State University of Semarang
  • Universitas Sains Al-Qur'an
  • Prince of Songkla University
  • Universiti Sains Islam Malaysia
  • Walisongo State Islamic University
  • Afiliasi tidak diketahui
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
  • Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Saffanah Binti Mohd Ab AzidPrince of Songkla University8
Lisdiana LisdianaState University of Semarang3
R. SusantiState University of Semarang2
Dyah Rini IndriyantiState University of Semarang2
Nanik WijayatiState University of Semarang2
Sri JuminiUniversitas Sains Al-Qur'an1
Sutikno MadnasriState University of Semarang1
Yatim Md NadrahUniversiti Sains Islam Malaysia1
H HamzahAfiliasi tidak diketahui1
F FatiatunUniversitas Sains Al-Qur'an1
Endang SusilaningsihState University of Semarang1
L. LastriState University of Semarang1
Apriliana DrastisiantiWalisongo State Islamic University1
E. KusumoState University of Semarang1
Zaneta Nur FaidaState University of Semarang1
Anida Hasna RahmatikaState University of Semarang1
Sistia Asfa FiqrotinnisaState University of Semarang1
Lia Intan HumairohAfiliasi tidak diketahui1
Citra PramestiAfiliasi tidak diketahui1
Wulan ChristijantiState University of Semarang1
Bagus Hammam FalahState University of Semarang1
Endah PeniatiState University of Semarang1
Addina Nur LuthfianiState University of Semarang1
Karsinah KarsinahAfiliasi tidak diketahui1
Widowati WidowatiState University of Semarang1
Margareta RahayuningsihState University of Semarang1
Suwarti SuwartiState University of Semarang1
Masturi MasturiState University of Semarang1
Fifin Dewi RatnasariAfiliasi tidak diketahui1
Kurnia Galuh Candra KiranaAfiliasi tidak diketahui1
Fadhillah ChoirunnisaAfiliasi tidak diketahui1
Ratih SukmawatiAfiliasi tidak diketahui1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://ijcc.chemoprev.org/index.php/ijcc/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Cytotoxic Effects of Cinnamon Powder and Lemongrass Oil-Enriched Roselle Tea on T47D Breast Cancer Cells</dc:title>
	<dc:creator>Aisyah, Sabila</dc:creator>
	<dc:creator>Cahyono, Edy</dc:creator>
	<dc:creator>WH, Nugrahaningsih</dc:creator>
	<dc:creator>Alighiri, Dante</dc:creator>
	<dc:creator>Alauhdin, Mohammad</dc:creator>
	<dc:creator>Zaky, Adrian Maulana</dc:creator>
	<dc:creator>Handayani, Tri</dc:creator>
	<dc:creator>Permatasari, Bella</dc:creator>
	<dc:description xml:lang="en-US">Breast cancer is the most prevalent cancer among women and is the leading cause of cancer-related mortality worldwide. This underlines the importance of preventive strategies to reduce the risk. Harnessing natural products like tea could be an alternative preventive strategy. In this study, the chemopreventive potential of roselle flower tea (Hibiscus sabdariffa L.) enriched with cinnamon oil (Cinnamomum burmannii) and lemongrass (Cymbopogon citratus) was evaluated. The tea was formulated using a stirred boiler tank and tested for its cytotoxicity against T47D cells using the MTT method. The cytotoxicity test showed that with the addition of cinnamon oil and lemongrass, roselle tea had more significant cytotoxic activity against T47D cancer cells than pristine roselle tea. Adding 5 g of cinnamon and lemongrass oil vapor for 15 seconds into the tea showed the highest cytotoxicity, with an IC50 of 730 μg/mL. This value is almost three times higher than without adding cinnamon oil and lemongrass. In conclusion, adding cinnamon oil and lemongrass to the roselle tea formulation can increase cytotoxic activity against T47D cancer cells, indicating its potential as a natural anti-cancer agent.Keywords: Chemopreventive, Cinnamon, Lemongrass, Roselle Tea, T47D Cells.</dc:description>
	<dc:publisher xml:lang="en-US">Indonesian Society for Cancer Chemoprevention</dc:publisher>
	<dc:contributor xml:lang="en-US">Universitas Negeri Semarang</dc:contributor>
	<dc:date>2024-10-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US"></dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ijcc.chemoprev.org/index.php/ijcc/article/view/499</dc:identifier>
	<dc:identifier>10.14499/indonesianjcanchemoprev15iss3pp186-197</dc:identifier>
	<dc:source xml:lang="en-US">Indonesian Journal of Cancer Chemoprevention; Vol 15, No 3 (2024); 186-197</dc:source>
	<dc:source>2355-8989</dc:source>
	<dc:source>2088-0197</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ijcc.chemoprev.org/index.php/ijcc/article/view/499/319</dc:relation>
	<dc:relation>https://ijcc.chemoprev.org/index.php/ijcc/article/downloadSuppFile/499/70</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2024 Indonesian Journal of Cancer Chemoprevention</dc:rights>
</oai_dc:dc>