THE EFFECTIVENESS OF GLUCOMANNAN AND NANO ACTIVATED-CARBON AS HYPERCHOLESTEROL-LOWERING AGENTS

Pasaribu, Gunawan Trisandi; Waluyo, Totok K.; Pari, Gustan; Hastuti, Novitri

doi:10.59465/ijfr.2020.7.2.155-164

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THE EFFECTIVENESS OF GLUCOMANNAN AND NANO ACTIVATED-CARBON AS HYPERCHOLESTEROL-LOWERING AGENTS

Indonesian Journal of Forestry Research · Vol. 7 No. 2 (2020) · hlm. 155–164

DOI: 10.59465/ijfr.2020.7.2.155-164
ISSN: 2406-8195, 2355-7079
Terbit: 2020-10-31
Penerbit: Association of Indonesian Forestry and Environment Researchers and Technicians
Bahasa: eng
Lisensi: creativecommons.org/licenses/by-nc-sa/4.0

Abstrak

Porang (konjac) plants have long been used as a food source and traditional medicine. Glucomannan derived from porang has been utilised for various uses such as antidiabetic and antihypercholesterolemia agent. This paper studies the mixture of porang flour and nano activated-carbon and its effect on the cholesterol activity of rats. The mixture of porang and activated carbon were subjected to test for male Sprague Dawley rats to test the antihypercholesterolemia activity. The result showed that concerted anticholesterol activity of porang and nano activated-carbon revealed the cholesterol level decreases in rat's blood. However, the different treatments of unleached and leached porang either leached porang and nano activated-carbon applied in the experiments showed that the levels of cholesterol decrease were slightly different (16–18%). Low glucomannan content as the alleged anticholesterol agent was regarded quite effective in lowering the cholesterol level in rat's blood and comparable with those of simvastatin which achieved 18% reduction. Therefore, it indicates potential utilisation as a functional food for a cholesterol-lowering agent. The involvement of activated carbon in the alleged anticholesterol agent (leached porang flour) did little in enhancing the cholesterol level decrease in rat's blood. The glucomannan in both leached porang flour and leached porang flour + nano activated-carbon shows potential utilisation as an anticholesterol agent. Yet, raw (unleached) porang is prospectively potential as a functional food for cholesterol-lowering.

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National Research and Innovation Agency
Hasanuddin University
IPB University
Indonesia University of Education
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Rekan penulis	Organisasi	Artikel bersama
Luciasih Agustini	National Research and Innovation Agency	2
Erlina Nurul Aini	National Research and Innovation Agency	2
Dian Anggraini Indrawan	National Research and Innovation Agency	2
Heru Satrio Wibisono	National Research and Innovation Agency	2
S Suhasman	Hasanuddin University	1
Andi Detti Yunianti	Hasanuddin University	1
Nurul Aprilia	Hasanuddin University	1
Saefudin Saefudin	Indonesia University of Education	1
Efrida Basri	Afiliasi tidak diketahui	1
Sofnie Sofnie	Afiliasi tidak diketahui	1
Elis Nina Herliyana	IPB University	1
Santiyo Wibowo	IPB University	1
Wasrin Syafii	IPB University	1

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Sumber metadata: OAI-PMH (metadata jurnal) https://ejournal.aptklhi.org/index.php/ijfr/oai, pertama di-harvest 8 Nov 2026, terakhir terlihat 8 Nov 2026.

Metadata asli (oai_dc)

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	<dc:title xml:lang="en-US">THE EFFECTIVENESS OF GLUCOMANNAN AND NANO ACTIVATED-CARBON AS HYPERCHOLESTEROL-LOWERING AGENTS</dc:title>
	<dc:creator>Pasaribu, Gunawan Trisandi</dc:creator>
	<dc:creator>Waluyo, Totok K.</dc:creator>
	<dc:creator>Pari, Gustan</dc:creator>
	<dc:creator>Hastuti, Novitri</dc:creator>
	<dc:subject xml:lang="en-US">Porang</dc:subject>
	<dc:subject xml:lang="en-US">anticholesterol</dc:subject>
	<dc:subject xml:lang="en-US">nano activated-carbon</dc:subject>
	<dc:subject xml:lang="en-US">glucomannan</dc:subject>
	<dc:description xml:lang="en-US">Porang (konjac) plants have long been used as a food source and traditional medicine. Glucomannan derived from porang has been utilised for various uses such as antidiabetic and antihypercholesterolemia agent. This paper studies the mixture of porang flour and nano activated-carbon and its effect on the cholesterol activity of rats. The mixture of porang and activated carbon were subjected to test for male Sprague Dawley rats to test the antihypercholesterolemia activity. The result showed that concerted anticholesterol activity of porang and nano activated-carbon revealed the cholesterol level decreases in rat's blood. However, the different treatments of unleached and leached porang either leached porang and nano activated-carbon applied in the experiments showed that the levels of cholesterol decrease were slightly different (16–18%). Low glucomannan content as the alleged anticholesterol agent was regarded quite effective in lowering the cholesterol level in rat's blood and comparable with those of simvastatin which achieved 18% reduction. Therefore, it indicates potential utilisation as a functional food for a cholesterol-lowering agent. The involvement of activated carbon in the alleged anticholesterol agent (leached porang flour) did little in enhancing the cholesterol level decrease in rat's blood. The glucomannan in both leached porang flour and leached porang flour + nano activated-carbon shows potential utilisation as an anticholesterol agent. Yet, raw (unleached) porang is prospectively potential as a functional food for cholesterol-lowering.</dc:description>
	<dc:publisher xml:lang="en-US">Association of Indonesian Forestry and Environment Researchers and Technicians</dc:publisher>
	<dc:date>2020-10-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.aptklhi.org/index.php/ijfr/article/view/467</dc:identifier>
	<dc:identifier>10.59465/ijfr.2020.7.2.155-164</dc:identifier>
	<dc:source xml:lang="en-US">Indonesian Journal of Forestry Research; Vol. 7 No. 2 (2020): Indonesian Journal of Forestry Research; 155-164</dc:source>
	<dc:source>2406-8195</dc:source>
	<dc:source>2355-7079</dc:source>
	<dc:source>10.59465/10.59465/ijfr.2020.7.2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.aptklhi.org/index.php/ijfr/article/view/467/130</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2020 Indonesian Journal of Forestry Research</dc:rights>
	<dc:rights xml:lang="en-US">http://creativecommons.org/licenses/by-nc-sa/4.0</dc:rights>
</oai_dc:dc>