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Systematic Review: Impact of Bisphenol-A (BPA) Exposure on Human Health

JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) · Vol. 17 No. 1 (2025) · hlm. 85–98

DOI
10.20473/jkl.v17i1.2025.85-98
ISSN
2540-881X, 1829-7285
Terbit
2025-01-31
Penerbit
Universitas Airlangga
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-nc-sa/4.0

Abstrak

Introduction: One chemical substance used in producing epoxy resins and polycarbonate (PC) is called bisphenol-A (BPA). Three million tons of the chemical compound bisphenol-A are still produced annually. The amount of BPA produced in 2015 was 7.7 million tons; by 2022, 10.8 million tons are anticipated to be made. This study aimed to ascertain the effects of bisphenol-A exposure on human health. Discussion: This study used a systematic review method by collecting articles through online databases with a publication range of 2018 - 2024. The article search used the PRISMA flow diagram. The findings of 30 articles all examined the impact of BPA exposure on health. The level of exposure to bisphenol-A can have an impact on health due to the nature of BPA EDC (Endocrine Disrupting Hormone) which can inhibit the activity of natural hormones in the body. Conclusion: The impact on human health due to exposure to bisphenol-A such as cancer, obesity, disruption of reproductive health, hypertension, disrupting child development, and also behavioral changes in children. Bisphenol-A enters the body not only through food packaging but also through air and dust contaminated with BPA. The length of exposure and concentration of BPA affect its effects on the human body.

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  • Diponegoro University
  • State University of Semarang
  • Universitas Bhakti Husada Indonesia
  • Afiliasi tidak diketahui
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  • Organisasi sama
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Rekan penulisOrganisasiArtikel bersama
Budiyono BudiyonoDiponegoro University3
Mursid RaharjoDiponegoro University2
SuhartonoDiponegoro University2
Mursid RaharjoDiponegoro University2
Citta Zahra PrimaliaDiponegoro University1
BudiyonoAfiliasi tidak diketahui1
Efa NugrohoState University of Semarang1
Cahya Tri PurnamiDiponegoro University1
Ayu IstiadaState University of Semarang1
Yuliani SetyaningsihDiponegoro University1
Qoni Mulia SagitaDiponegoro University1
M. Zen RahfiludinDiponegoro University1
Sumarah SumarahDiponegoro University1
Anies AniesDiponegoro University1
Agus SubagioDiponegoro University1
Nikie Astorina Yunita DewantiDiponegoro University1
Mutiara Afri SagitaDiponegoro University1
Suhartono SuhartonoDiponegoro University1
Apoina KartiniDiponegoro University1
Radhika WulandariDiponegoro University1
Nur Endah WahyuningsihDiponegoro University1
NurjazuliAfiliasi tidak diketahui1
Wulan MasyithahDiponegoro University1
Onny SetianiDiponegoro University1
SulistiyaniDiponegoro University1
Andi DaramussengDiponegoro University1
Aldi Prastya KurniawanDiponegoro University1
Tri JokoDiponegoro University1
Bibit Nasrokhatun DiniahUniversitas Bhakti Husada Indonesia1

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Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/JKL/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en-US">Systematic Review: Impact of Bisphenol-A (BPA) Exposure on Human Health</dc:title>
	<dc:creator>Sulistiyani, Sulistiyani</dc:creator>
	<dc:creator>Okti Iswari Triswindyaningrum</dc:creator>
	<dc:creator>Yusniar Hanani Darundiati</dc:creator>
	<dc:subject xml:lang="en-US">Bisphenol-A (BPA)</dc:subject>
	<dc:subject xml:lang="en-US">BPA exposure</dc:subject>
	<dc:subject xml:lang="en-US"> Food packaging</dc:subject>
	<dc:subject xml:lang="en-US">Hormonal effects</dc:subject>
	<dc:subject xml:lang="en-US">Human health</dc:subject>
	<dc:description xml:lang="en-US">Introduction: One chemical substance used in producing epoxy resins and polycarbonate (PC) is called bisphenol-A (BPA). Three million tons of the chemical compound bisphenol-A are still produced annually. The amount of BPA produced in 2015 was 7.7 million tons; by 2022, 10.8 million tons are anticipated to be made. This study aimed to ascertain the effects of bisphenol-A exposure on human health. Discussion: This study used a systematic review method by collecting articles through online databases with a publication range of 2018 - 2024. The article search used the PRISMA flow diagram. The findings of 30 articles all examined the impact of BPA exposure on health. The level of exposure to bisphenol-A can have an impact on health due to the nature of BPA EDC (Endocrine Disrupting Hormone) which can inhibit the activity of natural hormones in the body. Conclusion: The impact on human health due to exposure to bisphenol-A such as cancer, obesity, disruption of reproductive health, hypertension, disrupting child development, and also behavioral changes in children. Bisphenol-A enters the body not only through food packaging but also through air and dust contaminated with BPA. The length of exposure and concentration of BPA affect its effects on the human body.</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Airlangga</dc:publisher>
	<dc:date>2025-01-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:format>text/xml</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/JKL/article/view/58471</dc:identifier>
	<dc:identifier>10.20473/jkl.v17i1.2025.85-98</dc:identifier>
	<dc:source xml:lang="en-US">JURNAL KESEHATAN LINGKUNGAN ; Vol. 17 No. 1 (2025): JURNAL KESEHATAN LINGKUNGAN; 85-98</dc:source>
	<dc:source>2540-881X</dc:source>
	<dc:source>1829-7285</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/JKL/article/view/58471/31655</dc:relation>
	<dc:relation>https://e-journal.unair.ac.id/JKL/article/view/58471/31656</dc:relation>
	<dc:rights xml:lang="en-US">http://creativecommons.org/licenses/by-nc-sa/4.0</dc:rights>
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