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Havanensin-type Limonoids from the Stem Bark of Chisocheton pentandrus (Meliaceae)

Journal of Mathematical and Fundamental Sciences · Vol. 54 No. 3 (2023) · hlm. 302–310

DOI
10.5614/j.math.fund.sci.2023.54.3.2
ISSN
2338-5510, 2337-5760
Terbit
2023-05-15
Penerbit
Directorate for Research and Innovation (DRI) ITB
Bahasa
eng

Abstrak

A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of the isolated 1-5 were identified by NMR spectroscopy and HRTOFMS. Pentandricine E (1) displayed the highest cytotoxicity toward the MCF-7 breast cancer line with an IC50 value of 63.27 ± 0.21 mM.

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  • Padjadjaran University
  • Mulawarman University
  • Yamagata University
  • Tanjungpura University
  • Sultan Idris Education University
  • Universitas Gadjah Mada
  • National Research and Innovation Agency
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Rekan penulisOrganisasiArtikel bersama
Unang SupratmanPadjadjaran University13
Nurlelasari NurlelasariPadjadjaran University7
Desi HarnetiPadjadjaran University7
Rani MaharaniPadjadjaran University7
Kindi FarabiPadjadjaran University6
Tri MayantiPadjadjaran University6
Sofa FajriahNational Research and Innovation Agency5
Ace Tatang HidayatPadjadjaran University5
Al Arofatus NainiPadjadjaran University4
Erina HilmayantiPadjadjaran University3
Dewa Gede KatjaSam Ratulangi University3
Mohamad Nurul AzmiUniversiti Sains Malaysia3
Mohd Azlan NafiahSultan Idris Education University2
Khalijah AwangUniversity of Malaya2
Ricson P. HutagaolUniversitas Nusa Bangsa2
Darwati DarwatiPadjadjaran University2
Baso Didik HikmawanAfiliasi tidak diketahui1
Islamudin AhmadMulawarman University1
Laode RijaiMulawarman University1
Erwin SamsulMulawarman University1
Herman HermanMulawarman University1
Rachmat SahputraTanjungpura University1
Erlina ErlinaTanjungpura University1
Aimi ZulaikaTanjungpura University1
Tri Joko RaharjoState University of Semarang1
Tendy OktriawanUniversitas Gadjah Mada1
Nanang Rudianto ArieftaYamagata University1
Endang AstutiUniversitas Gadjah Mada1
Takuya KosekiYamagata University1
Laode RijaiAfiliasi tidak diketahui1
Hadi KuncoroMulawarman University1

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Sumber metadata: OAI-PMH (metadata jurnal) https://journals.itb.ac.id/index.php/jmfs/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc)
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	<dc:title xml:lang="en-US">Havanensin-type Limonoids from the Stem Bark of Chisocheton pentandrus (Meliaceae)</dc:title>
	<dc:creator>Runadi, Dudi</dc:creator>
	<dc:creator>Purnama, Purnama</dc:creator>
	<dc:creator>Salam, Supriatno </dc:creator>
	<dc:creator>Nurlelasari, Nulelasari</dc:creator>
	<dc:creator>Harneti, Desi</dc:creator>
	<dc:creator>Mayanti, Tri </dc:creator>
	<dc:creator>Maharani, Rani </dc:creator>
	<dc:creator>Supratman, Unang</dc:creator>
	<dc:creator>Shiono, Yoshihito</dc:creator>
	<dc:subject xml:lang="en-US">Chisocheton pentandrus</dc:subject>
	<dc:subject xml:lang="en-US">havanensin-type</dc:subject>
	<dc:subject xml:lang="en-US">MCF-7</dc:subject>
	<dc:subject xml:lang="en-US">pentandricine E</dc:subject>
	<dc:subject xml:lang="en-US">Chemistry</dc:subject>
	<dc:description xml:lang="en-US">A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of the isolated 1-5 were identified by NMR spectroscopy and HRTOFMS. Pentandricine E (1) displayed the highest cytotoxicity toward the MCF-7 breast cancer line with an IC50 value of 63.27 ± 0.21 mM.</dc:description>
	<dc:publisher xml:lang="en-US">Directorate for Research and Innovation (DRI) ITB</dc:publisher>
	<dc:date>2023-05-15</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journals.itb.ac.id/index.php/jmfs/article/view/19268</dc:identifier>
	<dc:identifier>10.5614/j.math.fund.sci.2023.54.3.2</dc:identifier>
	<dc:source xml:lang="en-US">Journal of Mathematical and Fundamental Sciences; Vol. 54 No. 3 (2023); 302-310</dc:source>
	<dc:source>2338-5510</dc:source>
	<dc:source>2337-5760</dc:source>
	<dc:source>10.5614/j.math.fund.sci.2023.54.3</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journals.itb.ac.id/index.php/jmfs/article/view/19268/6204</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 Journal of Mathematical and Fundamental Sciences</dc:rights>
</oai_dc:dc>