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Therapeutic Effects of BRC Functional Food from Indonesian Black Rice on Body Weight and Haematological Parameters in Obese Rats

Journal of Tropical Biodiversity and Biotechnology · Vol. 9 No. 1 (2024)

DOI
10.22146/jtbb.85847
ISSN
2540-9581, 2540-9573
Terbit
2024-01-12
Penerbit
Universitas Gadjah Mada
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-sa/4.0

Abstrak

Obesity increases the risk of various diseases. Black rice, renowned for its high anthocyanin content, is considered a potential functional food for preventing metabolic disorders. The current study investigated the effects of black rice crunch (BRC) on body weight and haematological profiles in obese rats. Rats were fed with high-fat diet to induce obesity and supplemented with different concentrations of BRC for 4 and 8 weeks. The results showed that high-fat diet effectively induced obesity, as evidenced by significant increase in body weight. Importantly, 75% BRC supplementation resulted in significant weight reduction in obese rats. Further analysis revealed an increase in erythrocyte numbers in obese groups supplemented with 75% BRC, but no significant changes in haemoglobin concentration or haematocrit percentage. Further investigation showed that 75% BRC led to a decrease in mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), and mean corpuscular volume (MCV), potentially affecting the size and concentration of haemoglobin within erythrocytes. The total leucocytes count increased with the high-fat diet, while BRC supplementation alone did not have significant impact. Lymphocyte percentage remained stable across the groups, indicating minimal influence of the dietary interventions. Neutrophil percentage varied initially but was not specific to BRC or the high-fat diet. Platelet count and distribution width were not significantly influenced, but mean platelet volume (MPV) increased after 8 weeks of BRC treatment, suggesting larger platelet sizes associated with obesity. Overall, the study provides important insights into the effects of BRC supplementation on body weight and haematological parameters related to obesity.

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  • Universitas Gadjah Mada
  • Universitas Al-Azhar Indonesia
  • Nara Institute of Science and Technology
  • National Research and Innovation Agency
  • Universitas Muhammadiyah Pontianak
  • Universitas Islam Negeri Sultan Maulana Hasanuddin Banten
  • Universitas Bangun Nusantara
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Rekan penulisOrganisasiArtikel bersama
Rumiyati RumiyatiUniversitas Gadjah Mada4
Woro Anindito Sri TunjungUniversitas Gadjah Mada4
M. MurwantokoAfiliasi tidak diketahui3
Langkah SembiringUniversitas Gadjah Mada3
Didik IndradewaUniversitas Gadjah Mada3
Firman AlamsyahUniversitas Al-Azhar Indonesia3
Hendry T.S.S.G. SaragihUniversitas Gadjah Mada3
Tri Rini NuringtyasUniversitas Gadjah Mada3
PUDJI ASTUTIAfiliasi tidak diketahui2
Charlie Ester de FretesNational Research and Innovation Agency2
Alfi Rizqi AmaliaUniversitas Gadjah Mada2
Radhiyah Mardhiyah HamidUniversitas Gadjah Mada2
Rifqi Zahroh JanatunaimUniversitas Gadjah Mada2
Donny WidiantoUniversitas Gadjah Mada2
Alfino SebastianUniversitas Gadjah Mada2
Wahyu Aristyaning PutriUniversitas Gadjah Mada2
Hanum Mukti RahayuUniversitas Muhammadiyah Pontianak2
Anis Uswatun KhasanahUniversitas Islam Negeri Sultan Maulana Hasanuddin Banten2
Yuni SineUniversitas Gadjah Mada2
Taryono TaryonoUniversitas Gadjah Mada2
Ratna Dewi EskundariUniversitas Bangun Nusantara2
Nastiti WijayantiUniversitas Gadjah Mada2
Nur Indah SeptrianiUniversitas Gadjah Mada2
Masashi KawaichiNara Institute of Science and Technology2
Muhammad AdnanUniversitas Islam Negeri Ar-Raniry1
Matin NuhamunadaUniversitas Gadjah Mada1
Rita MalizaAndalas University1

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Sumber metadata: OAI-PMH (metadata jurnal) https://jurnal.ugm.ac.id/jtbb/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en-US">Therapeutic Effects of BRC Functional Food from Indonesian Black Rice on Body Weight and Haematological Parameters in Obese Rats</dc:title>
	<dc:creator>Sofyantoro, Fajar</dc:creator>
	<dc:creator>Syam, Adi Mazdi</dc:creator>
	<dc:creator>Adania, Baik Aisyah</dc:creator>
	<dc:creator>Almunawar, Muhammad Fikri</dc:creator>
	<dc:creator>Nasution, Nurlita Putri Bela</dc:creator>
	<dc:creator>Hidayat, Rheina Faticha Asyamsa</dc:creator>
	<dc:creator>Mataram, Made Bagus Auriva</dc:creator>
	<dc:creator>Maharesi, Chesa Ekani</dc:creator>
	<dc:creator>Nurhidayah, Septika</dc:creator>
	<dc:creator>Purwestri, Yekti Asih</dc:creator>
	<dc:creator>Nuriliani, Ardaning</dc:creator>
	<dc:creator>Hidayati, Lisna</dc:creator>
	<dc:creator>Pratiwi, Rarastoeti</dc:creator>
	<dc:subject xml:lang="en-US">Biology;Biochemistry;Physiology</dc:subject>
	<dc:subject xml:lang="en-US">obesity; black rice; functional food; body weight; erythrocyte profile; leukocyte count</dc:subject>
	<dc:description xml:lang="en-US">Obesity increases the risk of various diseases. Black rice, renowned for its high anthocyanin content, is considered a potential functional food for preventing metabolic disorders. The current study investigated the effects of black rice crunch (BRC) on body weight and haematological profiles in obese rats. Rats were fed with high-fat diet to induce obesity and supplemented with different concentrations of BRC for 4 and 8 weeks. The results showed that high-fat diet effectively induced obesity, as evidenced by significant increase in body weight. Importantly, 75% BRC supplementation resulted in significant weight reduction in obese rats. Further analysis revealed an increase in erythrocyte numbers in obese groups supplemented with 75% BRC, but no significant changes in haemoglobin concentration or haematocrit percentage. Further investigation showed that 75% BRC led to a decrease in mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), and mean corpuscular volume (MCV), potentially affecting the size and concentration of haemoglobin within erythrocytes. The total leucocytes count increased with the high-fat diet, while BRC supplementation alone did not have significant impact. Lymphocyte percentage remained stable across the groups, indicating minimal influence of the dietary interventions. Neutrophil percentage varied initially but was not specific to BRC or the high-fat diet. Platelet count and distribution width were not significantly influenced, but mean platelet volume (MPV) increased after 8 weeks of BRC treatment, suggesting larger platelet sizes associated with obesity. Overall, the study provides important insights into the effects of BRC supplementation on body weight and haematological parameters related to obesity. </dc:description>
	<dc:publisher xml:lang="en-US">Universitas Gadjah Mada</dc:publisher>
	<dc:contributor xml:lang="en-US"></dc:contributor>
	<dc:date>2024-01-12</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
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	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.ugm.ac.id/jtbb/article/view/85847</dc:identifier>
	<dc:identifier>10.22146/jtbb.85847</dc:identifier>
	<dc:source xml:lang="en-US">Journal of Tropical Biodiversity and Biotechnology; Vol 9, No 1 (2024): March; jtbb85847</dc:source>
	<dc:source>2540-9581</dc:source>
	<dc:source>2540-9573</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.ugm.ac.id/jtbb/article/view/85847/37633</dc:relation>
	<dc:relation>https://journal.ugm.ac.id/jtbb/article/downloadSuppFile/85847/27242</dc:relation>
	<dc:relation>https://journal.ugm.ac.id/jtbb/article/downloadSuppFile/85847/27277</dc:relation>
	<dc:coverage xml:lang="en-US">South East Asia</dc:coverage>
	<dc:coverage xml:lang="en-US"></dc:coverage>
	<dc:coverage xml:lang="en-US"></dc:coverage>
	<dc:rights xml:lang="en-US">Copyright (c) 2024 Journal of Tropical Biodiversity and Biotechnology</dc:rights>
	<dc:rights xml:lang="en-US">http://creativecommons.org/licenses/by-sa/4.0</dc:rights>
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