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The Curative Activity of Isolated Fraction from Spathodea campanulata Beauv Stem Bark on Rats Exposed to Benzopyrene

Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences · Vol. 4 No. 3 (2014) · hlm. 161–165

DOI
10.11594/jtls.04.03.01
ISSN
2527-4376, 2087-5517
Terbit
2014-12-24
Penerbit
Journal of Tropical Life Science
Bahasa
eng

Abstrak

This paper reports a screening results of the secondary metabolites composed in Spathodea campanulata Beauv stem bark, evaluate inhibiting activity of malondialdehyde (MDA) on rats cancer model exposed with benzopyrene, and the histology of its lung. The secondary metabolite of the stem bark fraction consisted of alkaloids, flavonoids-phenolic, terpenoid and steroid compounds. The isolated fraction contained of these metabolites significantly indicate bioactivity by reducting of malondialdehyde (MDA) level, and also histology appearance of the lung tissue prepared from the benzopyrene-exposed rat indicated a curative activity.

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  • University of Brawijaya
  • Padjadjaran University
  • Universitas Islam Malang
  • Mulawarman University
  • National Research and Innovation Agency
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Rekan penulisOrganisasiArtikel bersama
Unang SupratmanPadjadjaran University2
Arie SrihardyastutieUniversity of Brawijaya2
Siti Mariyah UlfaUniversity of Brawijaya1
Momodou Salieu SoweUniversity of Brawijaya1
Arda Rista LestariUniversity of Brawijaya1
Eka NovitasariUniversity of Brawijaya1
Sofi NabilaUniversity of Brawijaya1
Tri ArdiyatiAfiliasi tidak diketahui1
Gatot CiptadiUniversity of Brawijaya1
Sutiman Bambang SumitroUniversity of Brawijaya1
Nurul Jadid MubarakatiUniversitas Islam Malang1
Alvi MillianaAfiliasi tidak diketahui1
Sanarto SantosoAfiliasi tidak diketahui1
Sumarno Reto PrawiroUniversity of Brawijaya1
Tinny Endang HernowatiUniversity of Brawijaya1
Avin Ainur Fitrianingsih‬University of Brawijaya1
Lailia Nur RachmaUniversity of Brawijaya1
Ace Tatang HidayatPadjadjaran University1
Sandra Amalia RiyadiPadjadjaran University1
Raihan Fathurrahman HasbillaPadjadjaran University1
Wahyu SafriansyahPadjadjaran University1
Susianti SusiantiPadjadjaran University1
Supriyanto SalamMulawarman University1
Ronny LesmanaPadjadjaran University1
Siti Nurul AfifahUniversity of Brawijaya1
Moh. Farid RahmanUniversity of Brawijaya1
Sofa FajriahNational Research and Innovation Agency1
Kindi FarabiPadjadjaran University1
Tri MayantiPadjadjaran University1
Al Arofatus NainiPadjadjaran University1
Faizah MairaPadjadjaran University1

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Sumber metadata: OAI-PMH (metadata jurnal) http://jtrolis.ub.ac.id/index.php/jtrolis/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">The Curative Activity of Isolated Fraction from Spathodea campanulata Beauv  Stem Bark on Rats Exposed to Benzopyrene</dc:title>
	<dc:creator xml:lang="en">Masruri, Masruri</dc:creator>
	<dc:creator xml:lang="en">Lutfillah, Mohamad</dc:creator>
	<dc:creator xml:lang="en">Sumaryanto, Ady</dc:creator>
	<dc:creator xml:lang="en">Retnowati, Rurini</dc:creator>
	<dc:creator xml:lang="en">Aulanni'am, Aulanni'am</dc:creator>
	<dc:description xml:lang="en">This paper reports a screening results of the secondary metabolites composed in Spathodea campanulata Beauv stem bark, evaluate inhibiting activity of malondialdehyde (MDA) on rats cancer model exposed with benzopyrene, and the histology of its lung. The secondary metabolite of the stem bark fraction consisted of alkaloids, flavonoids-phenolic, terpenoid and steroid compounds. The isolated fraction contained of these metabolites significantly indicate bioactivity by reducting of malondialdehyde (MDA) level, and also histology appearance of the lung tissue prepared from the benzopyrene-exposed rat indicated a curative activity.</dc:description>
	<dc:publisher xml:lang="en">Journal of Tropical Life Science</dc:publisher>
	<dc:date>2014-12-24</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://jtrolis.ub.ac.id/index.php/jtrolis/article/view/254</dc:identifier>
	<dc:identifier>10.11594/jtls.04.03.01</dc:identifier>
	<dc:source xml:lang="en">Journal of Tropical Life Science; Vol. 4 No. 3 (2014); 161-165</dc:source>
	<dc:source>2527-4376</dc:source>
	<dc:source>2087-5517</dc:source>
	<dc:source>10.11594/jtls.4.3</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://jtrolis.ub.ac.id/index.php/jtrolis/article/view/254/208</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2014 Journal of Tropical Life Science</dc:rights>
</oai_dc:dc>