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The effectiveness of wound caring technique with polyhexamethylene biguanide and dialkyl carbamoyl chloride to healing process duration of diabetic foot ulcer patient

Jurnal Keperawatan Padjadjaran · Vol. 11 No. 1 (2023) · hlm. 18–24

DOI
10.24198/jkp.v11i1.2152
ISSN
2442-7276, 2338-5324
Terbit
2023-04-27
Penerbit
Faculty of Nursing Universitas Padjadjaran
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-sa/4.0/

Abstrak

Background: Antimicrobial dressing on moist-based wound care is a successful wound care technique, especially for diabetes mellitus wounds. The moisture on wound can be made by closed wound care to reach a standard moisture in various wounds. The antimicrobial dressing type that can increase the wound healing is Polyhexamethylene biguanide (PHMB) and Dialkyl carbamoyl chloride (DACC). Polyhexamethylene biguanide can accelerate the tissue granulation and reduce the risk of infection. Dialkyl carbamoyl chloride is a part of moist wound healing with strong hydrophobic threat so the bacteria will be lifted and accelerate the wound healing process.  The aim of this research is to analyze the effect of healing technique  using Polyhexamethylene biguanide and Dialkyl carbamoyl chloride wound healing process on diabetic foot ulcer patients.  Methods: This research was quasi-experimental with 129 respondents.  The instruments were Bates Jensen’s observation sheet and data were processed by double linear regression. Results: It was obtained an average difference between the duration of the wound healing process between PHMB and DACC therapy with a p-value of 0.0005. Conclusion: The use of this type of DACC dressing is more effective against the duration of the healing process of diabetic foot ulcers because of the time needed for DACC to work  on killing bacteria in-vitro in 30 minutes compared to other dressing.

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  • Universitas Islam Negeri Ar-Raniry
  • Universitas Jambi
  • STIKes Widya Dharma Husada Tangerang
  • Universitas Medika Suherman
  • Universitas Halu Oleo
  • Andalas University
  • The Ohio State University
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Rekan penulisOrganisasiArtikel bersama
Heliati FajriahUniversitas Islam Negeri Ar-Raniry2
Umar Bin Abdul AzizUniversitas Islam Negeri Ar-Raniry2
Lutfi LutfiUniversitas Jambi1
Wiralestari WiralestariUniversitas Jambi1
Iskandar SamUniversitas Jambi1
Widya Sari WendryUniversitas Jambi1
Edi SuryaAfiliasi tidak diketahui1
Asmadi AsmadiAfiliasi tidak diketahui1
Muhammad RidhwanAfiliasi tidak diketahui1
Salami MahmudUniversitas Islam Negeri Ar-Raniry1
Umar Abdul AzizUniversitas Islam Negeri Ar-Raniry1
Yusran YusranUniversitas Halu Oleo1
Mushaddiq MushaddiqUniversitas Islam Negeri Ar-Raniry1
Safrul MulukUniversitas Islam Negeri Ar-Raniry1
Lidia AnjalianiUniversitas Islam Negeri Ar-Raniry1
Teuku ZulfikarUniversitas Islam Negeri Ar-Raniry1
Ridha MihartiUniversitas Islam Negeri Ar-Raniry1
Cut AttahirahUniversitas Islam Negeri Ar-Raniry1
Andriansyah AndriansyahUniversitas Islam Negeri Ar-Raniry1
Mahdalevia MahdaleviaUniversitas Islam Negeri Ar-Raniry1
Erika ShoviandaUniversitas Islam Negeri Ar-Raniry1
Arnis WardaniUniversitas Islam Negeri Ar-Raniry1
Andriansyah AndriansyahThe Ohio State University1
Jamaliah HasballahUniversitas Islam Negeri Ar-Raniry1
Diana PutriAndalas University1

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Sumber metadata: OAI-PMH (metadata jurnal) http://jkp.fkep.unpad.ac.id/index.php/jkp/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">The effectiveness of wound caring  technique with polyhexamethylene  biguanide and dialkyl carbamoyl  chloride to healing process duration of  diabetic foot ulcer patient</dc:title>
	<dc:creator>Armi, Armi</dc:creator>
	<dc:creator>Fitriani, Dewi</dc:creator>
	<dc:creator>Sartika, Mila</dc:creator>
	<dc:creator>Setiawan, Yana</dc:creator>
	<dc:subject xml:lang="en-US">diabetic foot ulcer</dc:subject>
	<dc:subject xml:lang="en-US">wound healing</dc:subject>
	<dc:description xml:lang="en-US">Background: Antimicrobial dressing on moist-based wound care is a successful wound care technique, especially for diabetes mellitus wounds. The moisture on wound can be made by closed wound care to reach a standard moisture in various wounds. The antimicrobial dressing type that can increase the wound healing is Polyhexamethylene biguanide (PHMB) and Dialkyl carbamoyl chloride (DACC). Polyhexamethylene biguanide can accelerate the tissue granulation and reduce the risk of infection. Dialkyl carbamoyl chloride is a part of moist wound healing with strong hydrophobic threat so the bacteria will be lifted and accelerate the wound healing process.  The aim of this research is to analyze the effect of healing technique  using Polyhexamethylene biguanide and Dialkyl carbamoyl chloride wound healing process on diabetic foot ulcer patients.  
Methods: This research was quasi-experimental with 129 respondents.  The instruments were Bates Jensen’s observation sheet and data were processed by double linear regression.
Results: It was obtained an average difference between the duration of the wound healing process between PHMB and DACC therapy with a p-value of 0.0005.
Conclusion: The use of this type of DACC dressing is more effective against the duration of the healing process of diabetic foot ulcers because of the time needed for DACC to work  on killing bacteria in-vitro in 30 minutes compared to other dressing.</dc:description>
	<dc:publisher xml:lang="en-US">Faculty of Nursing Universitas Padjadjaran</dc:publisher>
	<dc:date>2023-04-27</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://jkp.fkep.unpad.ac.id/index.php/jkp/article/view/2152</dc:identifier>
	<dc:identifier>10.24198/jkp.v11i1.2152</dc:identifier>
	<dc:source xml:lang="en-US">Jurnal Keperawatan Padjadjaran; Vol. 11 No. 1 (2023): Jurnal Keperawatan Padjadjaran; 18-24</dc:source>
	<dc:source>2442-7276</dc:source>
	<dc:source>2338-5324</dc:source>
	<dc:source>10.24198/jkp.v11i1</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://jkp.fkep.unpad.ac.id/index.php/jkp/article/view/2152/353</dc:relation>
	<dc:relation>10.24198/jkp.v8i1.1295.s649</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 Armi Armi, Dewi Fitriani, Mila Sartika, Yana Setiawan</dc:rights>
	<dc:rights xml:lang="en-US">https://creativecommons.org/licenses/by-sa/4.0/</dc:rights>
</oai_dc:dc>