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Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat

Jurnal Medik Veteriner · Vol. 4 No. 2 (2021) · hlm. 243–248

DOI
10.20473/jmv.vol4.iss2.2021.243-248
ISSN
2581-012X, 2615-7497
Terbit
2021-10-31
Penerbit
Universitas Airlangga
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-nc-sa/4.0

Abstrak

Monosodium glutamate (MSG) is a sodium salt from glutamic acid which is currently very popular to be used as a food flavoring ingredient to stimulate appetite. Exessive consumption of MSG can disrupt the balance of antioxidants and ROS, and cause the negative effects of oxidative stress on testes. Coffee has high chlorogenic acid, function for antioxidants and reduce the negative effect on cell damage in the testes. This study aims to analyze the effect of robusta coffee extract on histological of mice testes induced with MSG. This study was completely randomized design (CRD), using 20 male mice for 5 treatment groups: K+ (MSG 0.12 mg and Vitamin C 6 mg), K- (MSG 0.12 mg and CMC Na 0.1 ml), P1 (MSG 0.12 mg and RCE 0.1 mg), P2 (MSG 0.12 mg and RCE 0.2 mg), and P3 (MSG 0.12 mg and RCE 0.4 mg) orally for 42 days. Histophatological scores were analyzed with Saphiro-Wilk Test and Anova. There is no effect of increasing testicular weight. 0,12 mg MSG can cause a decrease in the number of spermatogonia and spermatocytes. 0,2 mg robusta coffee extract can maintain the number of spermatogonia and spermatocytes.

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Rekan penulisOrganisasiArtikel bersama
Amung Logam SaputroUniversitas Airlangga21
Maya Nurwartanti YunitaUniversitas Airlangga20
Ratih Novita PrajaUniversitas Airlangga18
Aditya YudhanaUniversitas Airlangga13
Soeharsono SoeharsonoUniversitas Airlangga11
Bodhi AgustonoUniversitas Airlangga10
Mohammad Anam Al ArifUniversitas Airlangga8
Muhammad Anam Al-ArifUniversitas Airlangga7
Widya Paramita LokapirnasariUniversitas Airlangga7
Mirni LamidUniversitas Airlangga6
Widya Paramita LokapirnasariUniversitas Airlangga6
Tjuk Imam RestiadiUniversitas Airlangga6
Nenny HarijaniUniversitas Airlangga6
Jola RahmahaniUniversitas Airlangga6
Trilas SardjitoUniversitas Airlangga5
Erma SafitriUniversitas Airlangga5
Nusdianto TriakosoUniversitas Airlangga5
Wiwiek TyasningsihUniversitas Airlangga5
Ira Sari YudaniayantiUniversitas Airlangga5
Imam MustofaUniversitas Airlangga5
Sri ChusniatiUniversitas Airlangga4
Tri Wahyu SuprayogiUniversitas Airlangga4
Ratna DamayantiUniversitas Airlangga4
Sri Pantja MadyawatiUniversitas Airlangga4
Yeni DhamayantiUniversitas Airlangga4
Sarmanu SarmanuUniversitas Airlangga3
Mustofa Helmi EffendiUniversitas Airlangga3
Suherni SusilowatiUniversitas Airlangga3
Boedi SetiawanUniversitas Airlangga3
Hermin RatnaniUniversitas Airlangga3
Sunaryo Hadi WarsitoUniversitas Airlangga3
Juni EkowatiUniversitas Airlangga2
Wiyanto HaditanojoAfiliasi tidak diketahui2
Tatik HernawatiUniversitas Airlangga2

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Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/JMV/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc)
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat</dc:title>
	<dc:creator>Plumeriastuti, Hani</dc:creator>
	<dc:creator>Weliyani, Trima</dc:creator>
	<dc:creator>Hamid, Iwan Sahrial</dc:creator>
	<dc:creator>Hidanah, Sri</dc:creator>
	<dc:creator>Prastiya, Ragil Angga</dc:creator>
	<dc:creator>Wibawati, Prima Ayu</dc:creator>
	<dc:subject xml:lang="en-US">monosodium glutamat</dc:subject>
	<dc:subject xml:lang="en-US">robusta coffee</dc:subject>
	<dc:subject xml:lang="en-US">testes</dc:subject>
	<dc:description xml:lang="en-US">Monosodium glutamate (MSG) is a sodium salt from glutamic acid which is currently very popular to be used as a food flavoring ingredient to stimulate appetite. Exessive consumption of MSG can disrupt the balance of antioxidants and ROS, and cause the negative effects of oxidative stress on testes. Coffee has high chlorogenic acid, function for antioxidants and reduce the negative effect on cell damage in the testes. This study aims to analyze the effect of robusta coffee extract on histological of mice testes induced with MSG. This study was completely randomized design (CRD), using 20 male mice for 5 treatment groups: K+ (MSG 0.12 mg and Vitamin C 6 mg), K- (MSG 0.12 mg and CMC Na 0.1 ml), P1 (MSG 0.12 mg and RCE 0.1 mg), P2 (MSG 0.12 mg and RCE 0.2 mg), and P3 (MSG 0.12 mg and RCE 0.4 mg) orally for 42 days. Histophatological scores were analyzed with Saphiro-Wilk Test and Anova. There is no effect of increasing testicular weight. 0,12 mg MSG can cause a decrease in the number of spermatogonia and spermatocytes. 0,2 mg robusta coffee extract can maintain the number of spermatogonia and spermatocytes.</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Airlangga</dc:publisher>
	<dc:date>2021-10-31</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/JMV/article/view/21809</dc:identifier>
	<dc:identifier>10.20473/jmv.vol4.iss2.2021.243-248</dc:identifier>
	<dc:source xml:lang="en-US">Jurnal Medik Veteriner; Vol. 4 No. 2 (2021): October; 243-248</dc:source>
	<dc:source>2581-012X</dc:source>
	<dc:source>2615-7497</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/JMV/article/view/21809/pdf</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2021 Trima Weliyani, Iwan Sahrial Hamid, Sri Hidanah, Ragil Angga Prastiya, Prima Ayu Wibawati</dc:rights>
	<dc:rights xml:lang="en-US">http://creativecommons.org/licenses/by-nc-sa/4.0</dc:rights>
</oai_dc:dc>