Akses terbuka Jurnal SINTA 1
Efficacy of Oregano Extract Ointment on Fibroblast Cells and Epidermis in Albino Rats with Excisional Wound Model
Jurnal Medik Veteriner · Vol. 6 No. 2 (2023) · hlm. 262–270
- ISSN
- 2581-012X, 2615-7497
- Terbit
- 2023-10-22
- Penerbit
- Universitas Airlangga
- Bahasa
- eng
Abstrak
This study aimed to determine the effect of oregano extract ointment therapy on the number of fibroblast cells and the epidermal thickness in excised wounds. The experimental animals used were 20 male Wistar strain albino rats, 12 weeks old, weighing 100–150 g, divided into 5 treatment groups i.e., (C-) not excised and without ointment, (C+) excised and without ointment, and the treatment group were excised using a 5 x 5 mm biopsy punch and treated with oregano extract ointment using concentrations of (T1) 3%, (T2) 6% and (T3) 9% twice daily for 14 days in an excised wound. The variables observed in this study were the number of fibroblast cells and the epidermal thickness by the HE staining method then measured using ImageJ. Data analysis used the One-Way ANOVA test followed by the Tukey test (p < 0,05). The results showed a decrease in the number of fibroblast cells and an increase in the epidermal thickness in the 6% concentration ointment. This study concluded that the administration of oregano extract ointment with a concentration of 6% was the optimal concentration in accelerating the final proliferative phase, characterized by a decrease in fibroblast cells and an increase in epidermal thickness.
Kata kunci
Jaringan kolaborasi para penulis
38 penulis · 166 tautan kepenulisan bersama · 13 lintas organisasi
Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.
- University of Brawijaya
- Universitas Gadjah Mada
- University of Copenhagen
- KONKLUSI - Kolaborasi Inklusi Konservasi (Yayasan)
- Afiliasi tidak diketahui
- Organisasi berbeda
- Organisasi sama
- Afiliasi tidak diketahui
- Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
| Rekan penulis | Organisasi | Artikel bersama |
|---|---|---|
| Rini Widayanti | Universitas Gadjah Mada | 2 |
| Irhamna Putri Rahmawati | Afiliasi tidak diketahui | 2 |
| Fidi Nur Aini Eka Puji Dameanti | University of Brawijaya | 2 |
| Nofan Rickyawan | University of Brawijaya | 2 |
| Sabhrina Gita Aninta | University of Copenhagen | 1 |
| Josephine Vanda Tirtayani | Afiliasi tidak diketahui | 1 |
| Nathan Rusli | Afiliasi tidak diketahui | 1 |
| Berta Alviyanto | Afiliasi tidak diketahui | 1 |
| Randy Kusuma | Afiliasi tidak diketahui | 1 |
| Adwitiya Irene Kumaralalita | Afiliasi tidak diketahui | 1 |
| Danuja Widigdaya | Afiliasi tidak diketahui | 1 |
| Safira Kinanti Pribadi | University of Brawijaya | 1 |
| Tania Salsabila Utari | University of Brawijaya | 1 |
| Fitri Ekasari | University of Brawijaya | 1 |
| Anastasia Cahyakusuma Wahyuningtyas | University of Brawijaya | 1 |
| Herdhanu Jayanto | KONKLUSI - Kolaborasi Inklusi Konservasi (Yayasan) | 1 |
| Muhamad Ferian Hendrasmara | University of Brawijaya | 1 |
| Dahliatul Qosimah | University of Brawijaya | 1 |
| Ajeng Aeka Nurmaningdyah | University of Brawijaya | 1 |
| Wawid Purwatiningsih | University of Brawijaya | 1 |
| Pradhana Kurniawan Cadiwirya | Afiliasi tidak diketahui | 1 |
| Dyah Ayu Oktavianie Ardhiana Pratama | University of Brawijaya | 1 |
| Ani Setianingrum | University of Brawijaya | 1 |
| Maulidi Robingi Mardiyani Wukirani | University of Brawijaya | 1 |
| Essly Hervianingsih Adha | University of Brawijaya | 1 |
| Sang Ayu Putri Aristya Dewi | University of Brawijaya | 1 |
| Yuliana Agustin | University of Brawijaya | 1 |
| Ida Bagus Gde Rama Wisesa | University of Brawijaya | 1 |
| Reza Yesica | University of Brawijaya | 1 |
| Shelly Kusumarini R | University of Brawijaya | 1 |
| Yudit Oktanella | University of Brawijaya | 1 |
| Gabriela Jeanne G.P | University of Brawijaya | 1 |
Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.