Melola Discovery

← Melola Discovery

Akses terbuka Jurnal SINTA 1

Long-term preclinical evaluation of a bare-metal stent (INA-Stent) in the iliac arteries of Macaca nemestrina

Jurnal Medik Veteriner · Vol. 9 No. 1 (2026) · hlm. 234–241

DOI
10.20473/jmv.vol9.iss1.2026.234-241
ISSN
2581-012X, 2615-7497
Terbit
2026-04-01
Penerbit
Universitas Airlangga
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-nc-sa/4.0

Abstrak

This study represents the final phase of a preclinical investigation assessing the outcomes of bare-metal stent (INA-Stent) implantation in the iliac arteries of Macaca nemestrina. The aim of the study was to evaluate the condition of the stent and to determine the presence or absence of restenosis and inflammation in the surrounding tissue. The INA-Stent was implanted in four healthy adult M. nemestrina. The animals were euthanized at 6- and 9-month intervals to enable clinical and histological evaluation of the implanted stents. This study specifically reports the terminal preclinical evaluation of the final M. nemestrina, in which the stent had been implanted for 36 months. The assessment was conducted to identify clinical signs and to determine the condition of the stent following surgical implantation in the iliac artery. The procedures included clinical evaluation, anesthesia, catheterization, intravascular optical coherence tomography (OCT), followed by euthanasia, necropsy, and scanning electron microscopy (SEM). Based on the SEM and OCT findings, the INA-Stent was well integrated into the arterial wall, did not induce chronic inflammation, and showed no evidence of restenosis at 36 months post-implantation.

Kata kunci

Jaringan kolaborasi para penulis

22 penulis · 76 tautan kepenulisan bersama · 19 lintas organisasi

Arahkan kursor atau ketuk sebuah nama untuk menyorot rekan penulisnya. Klik dua kali untuk membuka halaman penulis.

  • Universitas Gadjah Mada
  • Universitas Ahmad Dahlan
  • Rumah Sakit Umum Pusat Dr. Sardjito
  • University of Brawijaya
  • Organisasi berbeda
  • Organisasi sama
  • Afiliasi tidak diketahui
  • Garis lebih tebal = lebih banyak artikel bersama · lingkaran lebih besar = lebih banyak artikel
Tampilkan sebagai tabel
Rekan penulisOrganisasiArtikel bersama
Nunuk PurwantiUniversitas Gadjah Mada1
Aryan MoritaUniversitas Gadjah Mada1
Susmira Delta KusdinaUniversitas Gadjah Mada1
Solikhah SolikhahUniversitas Ahmad Dahlan1
Dyah SuryaniUniversitas Ahmad Dahlan1
Arif AndriyantoUniversitas Gadjah Mada1
Hevi WihadmadyatamiUniversitas Gadjah Mada1
Vista BudiariatiUniversitas Gadjah Mada1
Tri Wahyu PangestiningsihUniversitas Gadjah Mada1
Teguh BudipitojoUniversitas Gadjah Mada1
Khairunnisa AqiilahUniversitas Gadjah Mada1
Ariana ArianaUniversitas Gadjah Mada1
Golda Rani SaragihUniversitas Gadjah Mada1
Ulayatul KustiatiUniversity of Brawijaya1

Afiliasi berasal dari OpenAlex; metadata OAI-PMH jurnal tidak memuatnya. Penulis tanpa ID OpenAlex dicocokkan berdasarkan nama, sehingga dua orang bisa tergabung atau satu orang bisa terpisah.

Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/JMV/oai, pertama di-harvest 9 Nov 2026, terakhir terlihat 9 Nov 2026.
Metadata asli (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Long-term preclinical evaluation of a bare-metal stent (INA-Stent) in the iliac arteries of Macaca nemestrina</dc:title>
	<dc:creator>Wijayanti, Agustina Dwi</dc:creator>
	<dc:creator>Arifianto, Dinar</dc:creator>
	<dc:creator>Wijayanto, Hery</dc:creator>
	<dc:creator>Purnomo, Agus</dc:creator>
	<dc:creator>Budi, Setyo</dc:creator>
	<dc:creator>Taufiq, Nahar</dc:creator>
	<dc:creator>Yulianto, Heribertus Dedy Kusuma</dc:creator>
	<dc:creator>Siswomihardjo, Widowati</dc:creator>
	<dc:subject xml:lang="en-US">intravascular optical coherence tomography</dc:subject>
	<dc:subject xml:lang="en-US">INA-Stent</dc:subject>
	<dc:subject xml:lang="en-US">Macaca nemestrina</dc:subject>
	<dc:subject xml:lang="en-US">preclinical study</dc:subject>
	<dc:subject xml:lang="en-US">scanning electron microscopy</dc:subject>
	<dc:description xml:lang="en-US">This study represents the final phase of a preclinical investigation assessing the outcomes of bare-metal stent (INA-Stent) implantation in the iliac arteries of Macaca nemestrina. The aim of the study was to evaluate the condition of the stent and to determine the presence or absence of restenosis and inflammation in the surrounding tissue. The INA-Stent was implanted in four healthy adult M. nemestrina. The animals were euthanized at 6- and 9-month intervals to enable clinical and histological evaluation of the implanted stents. This study specifically reports the terminal preclinical evaluation of the final M. nemestrina, in which the stent had been implanted for 36 months. The assessment was conducted to identify clinical signs and to determine the condition of the stent following surgical implantation in the iliac artery. The procedures included clinical evaluation, anesthesia, catheterization, intravascular optical coherence tomography (OCT), followed by euthanasia, necropsy, and scanning electron microscopy (SEM). Based on the SEM and OCT findings, the INA-Stent was well integrated into the arterial wall, did not induce chronic inflammation, and showed no evidence of restenosis at 36 months post-implantation.</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Airlangga</dc:publisher>
	<dc:date>2026-04-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:format>text/xml</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/JMV/article/view/73893</dc:identifier>
	<dc:identifier>10.20473/jmv.vol9.iss1.2026.234-241</dc:identifier>
	<dc:source xml:lang="en-US">Jurnal Medik Veteriner; Vol. 9 No. 1 (2026): April; 234-241</dc:source>
	<dc:source>2581-012X</dc:source>
	<dc:source>2615-7497</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/JMV/article/view/73893/36900</dc:relation>
	<dc:relation>https://e-journal.unair.ac.id/JMV/article/view/73893/37711</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2026 Agustina Dwi Wijayanti, Dinar Arifianto, Hery Wijayanto, Agus Purnomo, Setyo Budi, Nahar Taufiq, Heribertus Dedy Kusuma Yulianto, Widowati Siswomihardjo</dc:rights>
	<dc:rights xml:lang="en-US">http://creativecommons.org/licenses/by-nc-sa/4.0</dc:rights>
</oai_dc:dc>