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THE EFFECT OF LOW-FIBER DIETS ON COLORECTAL CANCER INCIDENCE IN SOUTHEAST AND EAST ASIA: SYSTEMATIC REVIEW AND META-ANALYSIS

The Indonesian Journal of Public Health · Vol. 18 No. 2 (2023) · hlm. 353–365

DOI
10.20473/ijph.v18i2.2023.353-365
ISSN
2540-8836, 1829-7005
Terbit
2023-08-01
Penerbit
Universitas Airlangga
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-nc-sa/4.0

Abstrak

Introduction: Colorectal cancer is a malignant tumor that grows in the colon tissue. In the Asian region, in 2018, cases and deaths from colorectal cancer are highest in East Asia (there were 736,573 cases and 325,128 of them died) and Southeast Asia (there were 95,223 cases and 52,475 of them died). Aims: Several studies have been conducted regarding the effect of a low-fiber diet and an increased risk of colorectal cancer, but it still shows mixed results. Methods: This study is an unobstrutive study with a systematic review and meta-analysis method. Data sources came from 14 primary studies with a case-control study design that met the inclusion criteria. Data analysis was performed using CMA software trial version 3.0 with a confidence level of α = 5%. Research with low-fiber diet variables shows heterogeneous variations in results so that the chosen model is random effect model. Result: The analysis states that there was a significant relationship between a low-fiber diet (CI: 0.421–0.867) and an increased risk of colorectal cancer due to the role of soluble and insoluble fiber. Lack of intake of soluble fiber can decrease insulin action and blood sugar control or the production of short-chain fatty acids, whereas insufficient intake of insoluble fiber can increase the potential for interactions between mutagens and colonic mucosa. Conclusion: The results of the study are expected to be an input for a proper diet so that there is no increase in cases of colorectal cancer.

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  • Universitas Airlangga
  • State University of Medan
  • Rumah Sakit Dokter Soetomo
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Rekan penulisOrganisasiArtikel bersama
Trias MahmudionoUniversitas Airlangga2
Fatqiatul WulandariUniversitas Airlangga2
Nila Reswari HaryanaState University of Medan2
Mahmud Aditya RifqiUniversitas Airlangga2
Stefania Widya SetyaningtyasUniversitas Airlangga2
Rian DianaUniversitas Airlangga2
Aliffah Nurria NastitiUniversitas Airlangga2
Asri Meidyah AgustinUniversitas Airlangga2
Nursalam NursalamUniversitas Airlangga2
Kusnanto KusnantoUniversitas Airlangga2
Mira TrihariniUniversitas Airlangga2
Agus SulistyonoRumah Sakit Dokter Soetomo2
Zeni FirginingtyasUniversitas Airlangga1
Laila NurayatiUniversitas Airlangga1
Nathania Helsa F. LosongUniversitas Airlangga1
Brigita Rainy OktivaUniversitas Airlangga1
Denna Rahinda Yulia FanniUniversitas Airlangga1
Rizka Amalia HabibaUniversitas Airlangga1
Susila Rusdiana DewiUniversitas Airlangga1
Santi KusumastutiUniversitas Airlangga1
Ajeng Putri RahmanditaUniversitas Airlangga1
Lury Novita YustianingrumUniversitas Airlangga1
Intan Galih CorniaUniversitas Airlangga1
Rosita AndrianiUniversitas Airlangga1
Bambang PurwantoUniversitas Airlangga1
Dewi Retno SuminarUniversitas Airlangga1
Muhammad Dimas BimantaraUniversitas Airlangga1
Annisa Rachma Firdausi DarmawanUniversitas Airlangga1
Sheila Monica Kelly AmaliaAfiliasi tidak diketahui1
Susi HidayahUniversitas Airlangga1
Yurike Dhika AdhelaUniversitas Airlangga1
Diah IndrianiAfiliasi tidak diketahui1
Juwariyah JuwariyahUniversitas Airlangga1
Chusnul FadillaUniversitas Airlangga1
Ratna KuatiningsariUniversitas Airlangga1
Ade Lia RamadaniUniversitas Airlangga1
Martha Ria WijayantiUniversitas Airlangga1

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Sumber metadata: OAI-PMH (metadata jurnal) https://e-journal.unair.ac.id/IJPH/oai, pertama di-harvest 10 Nov 2026, terakhir terlihat 10 Nov 2026.
Metadata asli (oai_dc)
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">THE EFFECT OF LOW-FIBER DIETS ON COLORECTAL CANCER INCIDENCE IN SOUTHEAST AND EAST ASIA: SYSTEMATIC REVIEW AND META-ANALYSIS </dc:title>
	<dc:creator>Novianti, Tia Eka</dc:creator>
	<dc:creator>Rachmah, Qonita</dc:creator>
	<dc:creator>Adriani, Merryana</dc:creator>
	<dc:subject xml:lang="en-US">colorectal cancer</dc:subject>
	<dc:subject xml:lang="en-US">low-fiber diet</dc:subject>
	<dc:subject xml:lang="en-US">meta-analysis</dc:subject>
	<dc:subject xml:lang="en-US">systematic review</dc:subject>
	<dc:description xml:lang="en-US">Introduction : Colorectal cancer is a malignant tumor that grows in the colon tissue. In the Asian region, in 2018, cases and deaths from colorectal cancer are highest in East Asia (there were 736,573 cases and 325,128 of them died) and Southeast Asia (there were 95,223 cases and 52,475 of them died). Aims: Several studies have been conducted regarding the effect of a low-fiber diet and an increased risk of colorectal cancer, but it still shows mixed results. Methods: This study is an unobstrutive study with a systematic review and meta-analysis method. Data sources came from 14 primary studies with a case-control study design that met the inclusion criteria. Data analysis was performed using CMA software trial version 3.0 with a confidence level of α = 5%. Research with low-fiber diet variables shows heterogeneous variations in results so that the chosen model is random effect model. Result: The analysis states that there was a significant relationship between a low-fiber diet (CI: 0.421–0.867) and an increased risk of colorectal cancer due to the role of soluble and insoluble fiber. Lack of intake of soluble fiber can decrease insulin action and blood sugar control or the production of short-chain fatty acids, whereas insufficient intake of insoluble fiber can increase the potential for interactions between mutagens and colonic mucosa. Conclusion: The results of the study are expected to be an input for a proper diet so that there is no increase in cases of colorectal cancer.</dc:description>
	<dc:publisher xml:lang="en-US">Universitas Airlangga</dc:publisher>
	<dc:date>2023-08-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:format>text/xml</dc:format>
	<dc:identifier>https://e-journal.unair.ac.id/IJPH/article/view/22756</dc:identifier>
	<dc:identifier>10.20473/ijph.v18i2.2023.353-365</dc:identifier>
	<dc:source xml:lang="en-US">The Indonesian Journal of Public Health; Vol. 18 No. 2 (2023): THE INDONESIAN JOURNAL OF PUBLIC HEALTH; 353-365</dc:source>
	<dc:source>2540-8836</dc:source>
	<dc:source>1829-7005</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://e-journal.unair.ac.id/IJPH/article/view/22756/25570</dc:relation>
	<dc:relation>https://e-journal.unair.ac.id/IJPH/article/view/22756/25571</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2023 The Indonesian Journal of Public Health</dc:rights>
	<dc:rights xml:lang="en-US">https://creativecommons.org/licenses/by-nc-sa/4.0</dc:rights>
</oai_dc:dc>