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Effectiveness of Piper betle leaf infusion as a palpebral skin antiseptic

Universa Medicina · Vol. 28 No. 2 (2009) · hlm. 83–91

ISSN
2407-2230, 1907-3062
Terbit
2009-08-29
Penerbit
Faculty of Medicine, Universitas Trisakti
Bahasa
eng

Abstrak

The goal of an antiseptic is to eliminate or greatly reduce the number of microorganisms in the surgical field at the time of the surgery. The objective of this study was to verify the effectiveness of 20% Piper betle leaf infusion as an antiseptic solution in pre-surgery cataract patients. A clinical trial with partner-matching design was conducted on 31 pairs of eyelids. From each pair of eyelids, one eyelid was asigned to the Piper betle infusion group and the opposite one to the povidone-iodine group. The microorganisms were collected by swab from the patient’s palpebral skin, inoculated on nutrient agar, and incubated at 37oC for 20 hours. The antiseptic effectiveness was measured by counting the microbial colonies before and after administration of the antiseptic solutions. This study demonstrates that the mean colony counts after application of 20% Piper betle leaf infusion showed a significant reduction of 27-100% compared with those before administration (p=0.001). Mean colony counts after 10% povidone-iodine administration showed a significant reduction of 88-100% compared with the mean counts before the solution was applied (p=0.000). The 20% Piper betle infusion has an antiseptic potential. Nevertheless, the 10% povidone-iodine solution has more effective antiseptic capability.

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  • Universitas Trisakti
  • Universiti Sains Malaysia
  • Sam Ratulangi University
  • Loyola College
  • Université de Mostaganem
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  • Organisasi berbeda
  • Organisasi sama
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Rekan penulisOrganisasiArtikel bersama
Nany HairunisaUniversitas Trisakti3
Yasmine MashabiUniversitas Trisakti2
Asrenee Ab. RazakUniversiti Sains Malaysia1
Agnes Tineke Waney RorongUniversitas Trisakti1
Muhammad Amru Hammam El PutraUniversitas Trisakti1
Ade Dwi LestariUniversitas Trisakti1
Nabila AngelicaUniversitas Trisakti1
Muthia Ariana PutriUniversitas Trisakti1
Salma KhairunnisaUniversitas Trisakti1
Norsuhana OmarUniversiti Sains Malaysia1
Gusti G SuardanaAfiliasi tidak diketahui1
Widya ArtiniAfiliasi tidak diketahui1
Hosea Jaya EdySam Ratulangi University1
Edy ParwantoUniversitas Trisakti1
David TjahyadiUniversitas Trisakti1
Ashaolu Victoria OladimejiLoyola College1
Noureddine DjebliUniversité de Mostaganem1

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Sumber metadata: OAI-PMH (metadata jurnal) https://univmed.org/ejurnal/index.php/medicina/oai, pertama di-harvest 10 Nov 2026, terakhir terlihat 10 Nov 2026.
Metadata asli (oai_dc)
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	<dc:title xml:lang="en">Effectiveness of Piper betle leaf infusion as a palpebral skin antiseptic</dc:title>
	<dc:creator xml:lang="en">Amalia, Husnun</dc:creator>
	<dc:creator xml:lang="en">Sitompul, Ratna</dc:creator>
	<dc:creator xml:lang="en">Hutauruk, Johan</dc:creator>
	<dc:creator xml:lang="en">Andrianjah, Andrianjah</dc:creator>
	<dc:creator xml:lang="en">Mun’im, Abdul</dc:creator>
	<dc:subject xml:lang="en">Antiseptic</dc:subject>
	<dc:subject xml:lang="en">palpebral skin</dc:subject>
	<dc:subject xml:lang="en">Piper betle leaf infusion</dc:subject>
	<dc:subject xml:lang="en">povidone-iodine</dc:subject>
	<dc:description xml:lang="en">The goal of an antiseptic is to eliminate or greatly reduce the number of microorganisms in the surgical field at the time of the surgery. The objective of this study was to verify the effectiveness of 20% Piper betle leaf infusion as an antiseptic solution in pre-surgery cataract patients. A clinical trial with partner-matching design was conducted on 31 pairs of eyelids. From each pair of eyelids, one eyelid was asigned to the Piper betle infusion group and the opposite one to the povidone-iodine group. The microorganisms were collected by swab from the patient’s palpebral skin, inoculated on nutrient agar, and incubated at 37oC for 20 hours. The antiseptic effectiveness was measured by counting the microbial colonies before and after administration of the antiseptic solutions. This study demonstrates that the mean colony counts after application of 20% Piper betle leaf infusion showed a significant reduction of 27-100% compared with those before administration (p=0.001). Mean colony counts after 10% povidone-iodine administration showed a significant reduction of 88-100% compared with the mean counts before the solution was applied (p=0.000). The 20% Piper betle infusion has an antiseptic potential. Nevertheless, the 10% povidone-iodine solution has more effective antiseptic capability.</dc:description>
	<dc:publisher xml:lang="en">Faculty of Medicine, Universitas Trisakti</dc:publisher>
	<dc:date>2009-08-29</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://univmed.org/ejurnal/index.php/medicina/article/view/233</dc:identifier>
	<dc:source xml:lang="en">Universa Medicina; Vol. 28 No. 2 (2009); 83-91</dc:source>
	<dc:source>2407-2230</dc:source>
	<dc:source>1907-3062</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://univmed.org/ejurnal/index.php/medicina/article/view/233/204</dc:relation>
	<dc:relation>10.18051/univmed.v28i2.233</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2009 Husnun Amalia, Ratna Sitompul, Johan Hutauruk, Andrianjah Andrianjah, Abdul Mun’im</dc:rights>
</oai_dc:dc>