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Nephrolepis exaltata - Hibiscus rosa-sinensis combination herbal mask decreases levels of reactive oxygen species in nasal wash

Universa Medicina · Vol. 39 No. 3 (2020) · hlm. 184–191

DOI
10.18051/UnivMed.2020.v39.184-191
ISSN
2407-2230, 1907-3062
Terbit
2020-11-16
Penerbit
Faculty of Medicine, Universitas Trisakti
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-nc-sa/4.0

Abstrak

BackgroundPoor air and mask quality in the work environment increase the risks of inflammation, reactive oxygen species (ROS) production, ongoing oxidative stress, and superoxide dismutase 3 (SOD3) levels in the airways. The study aimed to investigate the effect of the Nephrolepis exaltata - Hibiscus rosa-sinensis (NE-HRS) combination herbal mask on the airways, as measured by ROS and SOD3 levels in the nasal wash of textile industry workers.MethodsThis was a pre- and post-test randomized controlled trial, consisting of 30 subjects with ³5-year working time, conducted for eight weeks and monitored every ten days. Subjects were randomized into 3 groups, regular surgical mask group (n=10), NE-HRS combination herbal mask group (n=10) and factory mask group (n=10). SOD3 and ROS levels were determined using ELISA. Data were analyzed with One-way ANOVA and multiple comparison tests.Results ROS levels decreased significantly in all groups (p=0.004). Regular surgical masks decreased ROS levels by 67.90 ± 50.66 pg/mL, NE-HRS combination herbal masks by 49.91 ± 45.06 pg/mL, and factory masks by 193.96 ± 128.36 pg/ml. SOD3 levels also decreased but not significantly (p=0.053). Differences in ROS levels between surgical mask and NE-HRS combination herbal mask was not significant (p=0.796). ConclusionHerbal masks laminated with NE-HRS combination significantly reduced ROS levels among textile industry workers. NE-HRS combination herbal masks have a similar protective effect to the regular surgical mask.

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  • Diponegoro University
  • State University of Semarang
  • Universitas Gadjah Mada
  • Sultan Agung Islamic University
  • Politeknik Bina Trada Semarang
  • Universitas Jambi
  • Padjadjaran University
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Rekan penulisOrganisasiArtikel bersama
Diana Nur AfifahDiponegoro University3
Fatikhu Yatuni AsmaraDiponegoro University3
Dian Puspita DewiDiponegoro University3
Reni Sulung UtamiDiponegoro University2
Herera RahajengDiponegoro University2
Neni SusilaningsihDiponegoro University2
Nani MaharaniDiponegoro University2
Hairul AsriDiponegoro University2
Anggorowati AnggorowatiDiponegoro University2
Saiful RidloState University of Semarang1
Andra NovitasariState University of Semarang1
Dwi HastutiUniversitas Jambi1
Zubaidah ZubaidahDiponegoro University1
Siti Yuyun Rahayu FitriPadjadjaran University1
Rafinda Naditya ArismunandarDiponegoro University1
Isniya NosartikaDiponegoro University1
Brigitta Natania Renata PurnomoDiponegoro University1
Indah SaraswatiDiponegoro University1
David PakayaTadulako University1
Aryoko WidodoDiponegoro University1
Endang LestariSultan Agung Islamic University1
Eti Poncorini PamungkasariSebelas Maret University1
Saekhol BakrieDiponegoro University1
Doni WidyandanaUniversitas Gadjah Mada1
Fitriana MawardiUniversitas Gadjah Mada1
Heru SuwardiantoDiponegoro University1
Selvia David RichardDiponegoro University1
Aryu CandraDiponegoro University1
Puspo Palupi Yekti HangujiwatDiponegoro University1
Dadi HamdaniSekolah Tinggi Ilmu Kesehatan Muhammadiyah Ciamis1
Indah Sri WahyuningsihSultan Agung Islamic University1
. SuhartonoAfiliasi tidak diketahui1
Untung SujiantoDiponegoro University1
Ethyca SariDiponegoro University1

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Sumber metadata: OAI-PMH (metadata jurnal) https://univmed.org/ejurnal/index.php/medicina/oai, pertama di-harvest 10 Nov 2026, terakhir terlihat 10 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Nephrolepis exaltata - Hibiscus rosa-sinensis  combination herbal mask decreases levels of reactive oxygen species in nasal wash</dc:title>
	<dc:creator xml:lang="en">Prasetyo, Awal</dc:creator>
	<dc:creator xml:lang="en">Ariani, Resti</dc:creator>
	<dc:creator xml:lang="en">Antari, Arlita Leniseptaria</dc:creator>
	<dc:creator xml:lang="en">Sadhana, Udadi</dc:creator>
	<dc:creator xml:lang="en">Miranti, Ika Pawitra</dc:creator>
	<dc:creator xml:lang="en">Kristina, Tri Nur</dc:creator>
	<dc:subject xml:lang="en">Herbal mask</dc:subject>
	<dc:subject xml:lang="en">ROS</dc:subject>
	<dc:subject xml:lang="en">SOD3</dc:subject>
	<dc:subject xml:lang="en">textile industry workers</dc:subject>
	<dc:description xml:lang="en">BackgroundPoor air and mask quality in the work environment increase the risks of inflammation, reactive oxygen species (ROS) production, ongoing oxidative stress, and superoxide dismutase 3 (SOD3) levels in the airways. The study aimed to investigate the effect of the Nephrolepis exaltata - Hibiscus rosa-sinensis (NE-HRS) combination herbal mask on the airways, as measured by ROS and SOD3 levels in the nasal wash of textile industry workers.MethodsThis was a pre- and post-test randomized controlled trial, consisting of 30 subjects with ³5-year working time, conducted for eight weeks and monitored every ten days. Subjects were randomized into 3 groups, regular surgical mask group (n=10), NE-HRS combination herbal mask group (n=10) and factory mask group (n=10). SOD3 and ROS levels were determined using ELISA. Data were analyzed with One-way ANOVA and multiple comparison tests.Results ROS levels decreased significantly in all groups (p=0.004). Regular surgical masks decreased ROS levels by 67.90 ± 50.66 pg/mL, NE-HRS combination herbal masks by 49.91 ± 45.06 pg/mL, and factory masks by 193.96 ± 128.36 pg/ml. SOD3 levels also decreased but not significantly (p=0.053). Differences in ROS levels between surgical mask and NE-HRS combination herbal mask was not significant (p=0.796). ConclusionHerbal masks laminated with NE-HRS combination significantly reduced ROS levels among textile industry workers. NE-HRS combination herbal masks have a similar protective effect to the regular surgical mask.</dc:description>
	<dc:publisher xml:lang="en">Faculty of Medicine, Universitas Trisakti</dc:publisher>
	<dc:date>2020-11-16</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://univmed.org/ejurnal/index.php/medicina/article/view/1004</dc:identifier>
	<dc:identifier>10.18051/UnivMed.2020.v39.184-191</dc:identifier>
	<dc:source xml:lang="en">Universa Medicina; Vol. 39 No. 3 (2020); 184-191</dc:source>
	<dc:source>2407-2230</dc:source>
	<dc:source>1907-3062</dc:source>
	<dc:source>10.18051/UnivMed.2020.v39.i3</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://univmed.org/ejurnal/index.php/medicina/article/view/1004/602</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2020 Awal Prasetyo, Resti Ariani, Arlita Leniseptaria Antari, Udadi Sadhana, Ika Pawitra Miranti, Tri Nur Kristina</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by-nc-sa/4.0</dc:rights>
</oai_dc:dc>