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Synthesis and Antibacterial Activity of Chitosan-Cinamaldehyde/AgNp Schiff Base Composite

VALENSI · Vol. ume No. 1 (2025) · hlm. 126–137

DOI
10.15408/jkv.v11i1.45121
ISSN
2548-3013, 2460-6065
Terbit
2025-06-17
Penerbit
Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University
Bahasa
eng
Lisensi
creativecommons.org/licenses/by-sa/4.0

Abstrak

Chitosan is a material that has antibacterial properties. Chitosan was modified with cinnamaldehyde to form chitosan Schiff base, which acts as a capping agent in the synthesis of silver nanoparticles. The Schiff base product was modified again into a silver nanoparticle Schiff base composite to improve its ability as a capping agent and improve its antibacterial properties. This study aims to synthesize a chitosan-cinnamaldehyde/AgNP Schiff base composite (CCSB/AgNP) as an active ingredient with excellent antibacterial properties. The first stage was the synthesis of a chitosan-cinnamaldehyde Schiff base. In the second stage, the synthesis of the chitosan/AgNP composite was carried out by adding STPP with sonication and a water bath. The third stage involved synthesizing of the CCSB/AgNP composite using the same method as the second stage employing both heating and non-heating as well as sonication and non-sonication. The product was characterized using a UV-Vis spectrophotometer, FT-IR, SEM-EDX, mapping, and AAS. Antibacterial tests were performed on the synthesized product using the Total Plate Count (TPC) method. Chitosan has a molecular weight of 338080 g/mol and a degree of deacetylation of 65.09%. The Schiff base product of chitosan-cinnamaldehyde is a brownish-yellow solid with a yield of 76.9% (w/w) and a degree of substitution of 87.02%. The presence of Ag was confirmed by EDX mapping, which revealed mass percentages of 0.26%, 1.00%, and 3.97% for C/AgNP-1, C/AgNP-2, and CCSB/AgNP-2, respectively. The chitosan/AgNP product has a yield of 97% (w/w) and an SPR effect at 439 nm. The synthesis of CCSB/AgNP obtained a dark green solid with a yield of 87% (w/w) and an SPR effect at 433 nm. The antibacterial activity test yielded the highest percentage reduction in the number of bacteria in CCSB/AgNP at 3 days of observation at 95.1%, and 7 days at 94.1%.

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  • Diponegoro University
  • Universiti Malaysia Terengganu
  • Institut Teknologi Indonesia
  • National Research and Innovation Agency
  • Universitas Pertamina
  • State University of Semarang
  • Hasanuddin University
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Rekan penulisOrganisasiArtikel bersama
Nor Basid Adiwibawa PrasetyaDiponegoro University12
Mukhammad Asy’ariDiponegoro University6
Hadiyanto HadiyantoDiponegoro University5
Yosie AndrianiUniversiti Malaysia Terengganu4
Linda Aliffia YoshiInstitut Teknologi Indonesia3
Enjarlis EnjarlisInstitut Teknologi Indonesia2
Athanasia Amanda SeptevaniNational Research and Innovation Agency2
Andin Vita AmaliaState University of Semarang1
Tri Retnaningsih SoeprobowatiDiponegoro University1
J. JoelianingsihInstitut Teknologi Indonesia1
R RatnawatiHasanuddin University1
S. SlametUniversity of Indonesia1
Yuli Amalia HusnilInstitut Teknologi Indonesia1
Abdullah AbdullahDiponegoro University1
Hamid HamidDiponegoro University1
Alifah Husnun KholieqohAfiliasi tidak diketahui1
Rosmiati RosmiatiNational Research and Innovation Agency1
Nur Asniza AzizUniversitas Ma Chung1
Murni Nur Islamiah KassimUniversiti Malaysia Terengganu1
Efriyana OksalUniversity of Palangka Raya1
Kamariah BakarUniversiti Malaysia Terengganu1
Desy Fitrya SyamsumirUniversiti Malaysia Terengganu1
Yeong Yik SungUniversiti Malaysia Terengganu1
Dwi HudiyantiDiponegoro University1
Tengku Sifzizul Tengku MuhammadUniversiti Malaysia Terengganu1
Dessy AriyantiDiponegoro University1
Adrianus Kristyo PrabowoDiponegoro University1
Agnes Priska TiarasukmaDiponegoro University1
Ika Dyah WidharyantiUniversitas Pertamina1
Muhammad Andiri HendrawanUniversitas Pertamina1
Dilla DayantiDiponegoro University1
Yayuk AstutiDiponegoro University1
Achmad Yanuar MaulanaDong-A University1
K KhoirunnisaDiponegoro University1

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Sumber metadata: OAI-PMH (metadata jurnal) http://journal.uinjkt.ac.id/index.php/valensi/oai, pertama di-harvest 10 Nov 2026, terakhir terlihat 10 Nov 2026.
Metadata asli (oai_dc) 
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	<dc:title xml:lang="en">Synthesis and Antibacterial Activity of Chitosan-Cinamaldehyde/AgNp Schiff Base Composite</dc:title>
	<dc:creator xml:lang="en">Huda, Muhammad Badrul </dc:creator>
	<dc:creator xml:lang="en">Rinaryadi, Kemilau Permata Hati </dc:creator>
	<dc:creator xml:lang="en">Ngadiwiyana, Ngadiwiyana</dc:creator>
	<dc:creator xml:lang="en">Christwardana, Marcelinus </dc:creator>
	<dc:creator xml:lang="en">Sarjono, Purbowatiningrum Ria </dc:creator>
	<dc:creator xml:lang="en">Ismiyarto, Ismiyarto</dc:creator>
	<dc:subject xml:lang="en">Antibacterial</dc:subject>
	<dc:subject xml:lang="en">chitosan</dc:subject>
	<dc:subject xml:lang="en">nanoparticle Ag</dc:subject>
	<dc:subject xml:lang="en">Schiff base </dc:subject>
	<dc:description xml:lang="en">Chitosan is a material that has antibacterial properties. Chitosan was modified with cinnamaldehyde to form chitosan Schiff base, which acts as a capping agent in the synthesis of silver nanoparticles. The Schiff base product was modified again into a silver nanoparticle Schiff base composite to improve its ability as a capping agent and improve its antibacterial properties. This study aims to synthesize a chitosan-cinnamaldehyde/AgNP Schiff base composite (CCSB/AgNP) as an active ingredient with excellent antibacterial properties. The first stage was the synthesis of a chitosan-cinnamaldehyde Schiff base. In the second stage, the synthesis of the chitosan/AgNP composite was carried out by adding STPP with sonication and a water bath. The third stage involved synthesizing of the CCSB/AgNP composite using the same method as the second stage employing both heating and non-heating as well as sonication and non-sonication. The product was characterized using a UV-Vis spectrophotometer, FT-IR, SEM-EDX, mapping, and AAS. Antibacterial tests were performed on the synthesized product using the Total Plate Count (TPC) method. Chitosan has a molecular weight of 338080 g/mol and a degree of deacetylation of 65.09%. The Schiff base product of chitosan-cinnamaldehyde is a brownish-yellow solid with a yield of 76.9% (w/w) and a degree of substitution of 87.02%. The presence of Ag was confirmed by EDX mapping, which revealed mass percentages of 0.26%, 1.00%, and 3.97% for C/AgNP-1, C/AgNP-2, and CCSB/AgNP-2, respectively. The chitosan/AgNP product has a yield of 97% (w/w) and an SPR effect at 439 nm. The synthesis of CCSB/AgNP obtained a dark green solid with a yield of 87% (w/w) and an SPR effect at 433 nm. The antibacterial activity test yielded the highest percentage reduction in the number of bacteria in CCSB/AgNP at 3 days of observation at 95.1%, and 7 days at 94.1%. </dc:description>
	<dc:publisher xml:lang="en">Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University</dc:publisher>
	<dc:date>2025-06-17</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://journal.uinjkt.ac.id/index.php/valensi/article/view/45121</dc:identifier>
	<dc:identifier>10.15408/jkv.v11i1.45121</dc:identifier>
	<dc:source xml:lang="en">Jurnal Kimia Valensi; Jurnal Kimia VALENSI,  Volume 11, No. 1, May 2025; 126-137</dc:source>
	<dc:source>2548-3013</dc:source>
	<dc:source>2460-6065</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://journal.uinjkt.ac.id/index.php/valensi/article/view/45121/17969</dc:relation>
	<dc:rights xml:lang="en">Copyright (c) 2025 Ismiyarto - Ismiyarto</dc:rights>
	<dc:rights xml:lang="en">https://creativecommons.org/licenses/by-sa/4.0</dc:rights>
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