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Identifikasi Komponen Metabolit Sekunder yang Menentukan Toksisitas Ekstrak Daun Lansium domesticum Varietas Langsat

SAINS : Jurnal Kimia & Pendidikan Kimia · Vol. 11 No. 2 (2023) · pp. 144–147

ISSN
2964-8084, 2301-5934
Published
2023-01-15
Publisher
PKimia FKIP Universitas Halu Oleo
Language
eng

Abstract

Research has been carried out on Secondary Metabolite Components Determining Toxicity of Lansium domesticum Leaf Extract of Langsat Variety with the aim of analyzing the toxicity of n-hexane, ethyl acetate and methanol fractions as well as identifying secondary metabolite components that determine the toxicity of Lansium domesticum leaf extract of Langsat variety. The method used was liquid-liquid extraction, then each fraction was tested for phytochemicals and tested for toxicity using the Brine Shrimp Lethality Test (BSLT) method. The results showed that the n-hexane fraction was dominated by steroids with a few polyphenols and tannins. The ethyl acetate fraction is dominated by polyphenols, tannins and alkaloids and still contains a small amount of steroids. The methanol fraction contains small amounts of polyphenols, tannins and saponins. Each fraction showed toxic activity against Artemia salina Leach larvae. The ethyl acetate fraction showed the highest toxic activity (LC50 of 75.24 ppm), followed by the methanol fraction (LC50 of 104.97 ppm) and lastly the n-hexane fraction (LC50 of 309.03 ppm). The components of secondary metabolites that greatly determine the toxic activity of the methanol extract of the leaves of L. domesticum of the langsat variety are polyphenols and tannins.

Keywords

Collaboration network of the authors

40 authors · 98 co-authorship links · showing the 40 most connected

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  • Universitas Halu Oleo
  • Affiliation unknown
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  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
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Co-authorOrganisationJoint articles
Jamal HarimudinAffiliation unknown6
La Ode ResteleAffiliation unknown4
Jufri KarimUniversitas Halu Oleo3
Djafar MeyAffiliation unknown3
la Ode RustamAffiliation unknown2
Yoo Eka Yana KansilUniversitas Halu Oleo2
Safrudin SaharAffiliation unknown2
Ahmad HidayatAffiliation unknown2
Weka WidayatiAffiliation unknown2
Jamal HarimuddinAffiliation unknown2
Akbardiansyah AkbardiansyahAffiliation unknown2
Muhammad AnasAffiliation unknown1
Erniwati ErniwatiAffiliation unknown1
wa Ode YusriaAffiliation unknown1
Ahmad IskandarAffiliation unknown1
La Ode KaimudinAffiliation unknown1
Suriana SurianaAffiliation unknown1
Musadar MappasombaAffiliation unknown1
Fahyuddin FahyuddinAffiliation unknown1
Jamili JamiliAffiliation unknown1
Karsadi KarsadiAffiliation unknown1
Hamuni HamuniAffiliation unknown1
Hasbullah SyafAffiliation unknown1
Eka AprianaAffiliation unknown1
Azhar BafadalUniversitas Halu Oleo1
Mukhtar AbuUniversitas Halu Oleo1
Lade Albar KalzaUniversitas Halu Oleo1
Suhadi SuhadiAffiliation unknown1
Sinarwaty SinarwatyAffiliation unknown1
Endro SukotjoAffiliation unknown1
La HataniAffiliation unknown1
Adnan HakimAffiliation unknown1
Anita IndirasaryAffiliation unknown1
Lukman YunusAffiliation unknown1
Eulisa EulisaAffiliation unknown1
La Onu OlaAffiliation unknown1
Ade Rahmasari HarsonoAffiliation unknown1
Sri Fera RahayuAffiliation unknown1
Muh. MagribiAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/SAINS/oai, first harvested 30 Okt 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Identifikasi Komponen Metabolit Sekunder yang Menentukan Toksisitas Ekstrak Daun Lansium domesticum Varietas Langsat</dc:title>
	<dc:creator>Fitriani, Fitriani</dc:creator>
	<dc:subject xml:lang="en-US"></dc:subject>
	<dc:subject xml:lang="en-US">Keywords: Langsat Leaf, Lansium domesticum,Phytochemical, Toxycity, BSLT</dc:subject>
	<dc:subject xml:lang="en-US"></dc:subject>
	<dc:description xml:lang="en-US">Research has been carried out on Secondary Metabolite Components Determining Toxicity of Lansium domesticum Leaf Extract of Langsat Variety with the aim of analyzing the toxicity of n-hexane, ethyl acetate and methanol fractions as well as identifying secondary metabolite components that determine the toxicity of Lansium domesticum leaf extract of Langsat variety. The method used was liquid-liquid extraction, then each fraction was tested for phytochemicals and tested for toxicity using the Brine Shrimp Lethality Test (BSLT) method. The results showed that the n-hexane fraction was dominated by steroids with a few polyphenols and tannins. The ethyl acetate fraction is dominated by polyphenols, tannins and alkaloids and still contains a small amount of steroids. The methanol fraction contains small amounts of polyphenols, tannins and saponins. Each fraction showed toxic activity against Artemia salina Leach larvae. The ethyl acetate fraction showed the highest toxic activity (LC50 of 75.24 ppm), followed by the methanol fraction (LC50 of 104.97 ppm) and lastly the n-hexane fraction (LC50 of 309.03 ppm). The components of secondary metabolites that greatly determine the toxic activity of the methanol extract of the leaves of L. domesticum of the langsat variety are polyphenols and tannins.</dc:description>
	<dc:publisher xml:lang="en-US">PKimia FKIP Universitas Halu Oleo</dc:publisher>
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	<dc:date>2023-01-15</dc:date>
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	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
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	<dc:identifier>https://ojs.uho.ac.id/index.php/SAINS/article/view/29072</dc:identifier>
	<dc:source xml:lang="en-US">SAINS : Jurnal Kimia  Pendidikan Kimia; Vol 11, No 2 (2022): EDISI DESEMBER 2022; 144-147</dc:source>
	<dc:source>2964-8084</dc:source>
	<dc:source>2301-5934</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ojs.uho.ac.id/index.php/SAINS/article/view/29072/pdf</dc:relation>
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	<dc:rights xml:lang="en-US">Copyright (c) 2023 SAINS : Jurnal Kimia  Pendidikan Kimia</dc:rights>
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