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Sintetis Senyawa Caffeic Acid Phenethyl Ester dan Karakterisasinya Menggunakan 1H NMR

SAINS : Jurnal Kimia & Pendidikan Kimia · Vol. 10 No. 2 (2021) · pp. 41–49

ISSN
2964-8084, 2301-5934
Published
2021-12-02
Publisher
PKimia FKIP Universitas Halu Oleo
Language
eng

Abstract

Thesynthesis ofcaffeic acid phenethyl ester (CAPE) and its characterization using 1H NMR has been carried out. This research aims to discloseseveral potential ways of CAPE synthesis.The study was conducted by reacting some precursors in effort to produce CAPE.The progress of the synthesis was monitored using TLC and the characterization of the synthetic products was performed with 1H NMR.Three different approaches in effort to synthesize CAPE were conducted.The first approach was a direct rection between caffeoyl chloride and phenethyl alcohol. The second approach was including a protection using benzyl group and the last one was utilizing acetyl protecting groups where both these protecting groups were used to protect the catechol groups of the caffeic acidmoiety. However, the first and second methods failed to achieve the compound target, CAPE. There was only one procedure hasbeen successful, namely the reaction between phenethyl ester with acetyl-protected caffeic acidresulting inthe production of the synthetic compound target, CAPE, as much as 42%

Keywords

Collaboration network of the authors

13 authors · 26 co-authorship links

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  • Universitas Halu Oleo
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Ida UsmanAffiliation unknown1
Waode Sukmawati ArsyadAffiliation unknown1
M. JahidingAffiliation unknown1
Mashuni MashuniAffiliation unknown1
Muh. Aksan DermawanAffiliation unknown1
Fitri Handayani HamidAffiliation unknown1
Laode Abdul KadirAffiliation unknown1
Andi Laila NugrawatyAffiliation unknown1
Andi SeptianaUniversitas Halu Oleo1
Lina LestariUniversitas Halu Oleo1
La Ode AhmadAffiliation unknown1
Rasas RayaAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/SAINS/oai, first harvested 30 Okt 2026, last seen 30 Okt 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Sintetis Senyawa Caffeic Acid Phenethyl Ester dan Karakterisasinya Menggunakan 1H NMR</dc:title>
	<dc:creator>Kadidae, La Ode</dc:creator>
	<dc:subject xml:lang="en-US"></dc:subject>
	<dc:subject xml:lang="en-US">CAPE, protecting groups, 1H NMR</dc:subject>
	<dc:subject xml:lang="en-US"></dc:subject>
	<dc:description xml:lang="en-US">Thesynthesis ofcaffeic acid phenethyl ester (CAPE) and its characterization using 1H NMR has been carried out. This research aims to discloseseveral potential ways of CAPE synthesis.The study was conducted by reacting some precursors in effort to produce CAPE.The progress of the synthesis was monitored using TLC and the characterization of the synthetic products was performed with 1H NMR.Three different approaches in effort to synthesize CAPE were conducted.The first approach was a direct rection between caffeoyl chloride and phenethyl alcohol. The second approach was including a protection using benzyl group and the last one was utilizing acetyl protecting groups where both these protecting groups were used to protect the catechol groups of the caffeic acidmoiety. However, the first and second methods failed to achieve the compound target, CAPE. There was only one procedure hasbeen successful, namely the reaction between phenethyl ester with acetyl-protected caffeic acidresulting inthe production of the synthetic compound target, CAPE, as much as 42%</dc:description>
	<dc:publisher xml:lang="en-US">PKimia FKIP Universitas Halu Oleo</dc:publisher>
	<dc:contributor xml:lang="en-US"></dc:contributor>
	<dc:date>2021-12-02</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
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	<dc:type xml:lang="en-US">Peer-reviewed Article</dc:type>
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	<dc:identifier>https://ojs.uho.ac.id/index.php/SAINS/article/view/25592</dc:identifier>
	<dc:source xml:lang="en-US">SAINS : Jurnal Kimia  Pendidikan Kimia; Vol 10, No 2 (2021): EDISI DESEMBER 2021; 41-49</dc:source>
	<dc:source>2964-8084</dc:source>
	<dc:source>2301-5934</dc:source>
	<dc:language>eng</dc:language>
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	<dc:rights xml:lang="en-US">Copyright (c) 2021 SAINS : Jurnal Kimia  Pendidikan Kimia</dc:rights>
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