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Uji Toksisitas Akut Ekstrak Metanol Daun Keji Beling (Strobilanthes crispus BI.), Batang dan Bunga Jarak Tintir (Jatropha multifida L.) terhadap Larva Artemia salina Leach dengan Metode Brine Shrimp Lethality Test (BSLT)

Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan · Vol. 1 No. 1 (2015)

DOI
10.33772/pharmauho.v1i1.3456
ISSN
2715-4181
Published
2015-04-12
Publisher
Fakultas Farmasi Universitas Halu Oleo
Language
eng

Abstract

Research on the acute toxicity test of methanol extracts of keji beling leaves (Strobilanthes crispus BI.), stems and flowers of jarak tintir (Jatropha multifida L.) against Artemia salina Leach larvae using Brine Shrimp Lethality Test method (BSLT) had been carried out. The purpose of this study was to determine the potency of acute toxicity of methanol extract which were shown by LC50 value. In this research, the sample methanol were obtained from a previous research. Acute toxicity tests was conducted to determine the LC50 values of plant extracts according to the method of Brine Shrimp Lethality Test. Results of the research showed methanol extract of keji beling leaves were not toxic with LC50 value 4427,95 μg/mL, meanwhile stems and flowers of jarak tintir had low toxicity with LC50 225,09 and 253,26 μg/mL, respectively. The value of LC50 influenced by the content of secondary metabolites in plants.Keywords: Acute toxicity test, Brine Shrimp Lethality Test, LC50, J. multifida, S. crispus

Collaboration network of the authors

40 authors · 117 co-authorship links · showing the 40 most connected

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Universitas Halu Oleo
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Sahidin SahidinAffiliation unknown5
Nur Illiyyin AkibAffiliation unknown4
Mentarry BafadalAffiliation unknown4
Mustamin AnggoUniversitas Halu Oleo3
Muhammad Hajrul MalakaAffiliation unknown3
Fadhliyah MalikAffiliation unknown3
Henny KasmawatiUniversitas Halu Oleo3
Hafiludin SamparadjaAffiliation unknown2
S SabarudinAffiliation unknown2
Suryani SuryaniUniversitas Halu Oleo2
Ramadhan TosepuUniversitas Halu Oleo1
Rini RiniUniversitas Halu Oleo1
Nur Arfa YantiAffiliation unknown1
Sri AmbardiniUniversitas Halu Oleo1
Dirvamena BoerUniversitas Halu Oleo1
Darwis SulemanUniversitas Halu Oleo1
Nurlena IkawatiAffiliation unknown1
Ardiyanti ArdiyantiAffiliation unknown1
Nurhayani HMAffiliation unknown1
Muhammad Juharisman SaputraAffiliation unknown1
Wa BaaneAffiliation unknown1
Harleli HarleliUniversitas Halu Oleo1
Sartiah YusranAffiliation unknown1
Muhammad SudiaAffiliation unknown1
Sri WahyuningsihAffiliation unknown1
Kadir KadirAffiliation unknown1
Misryati MisryatiAffiliation unknown1
Safrin SafrinAffiliation unknown1
Novayanti NovayantiAffiliation unknown1
Rahmat AlimuddinAffiliation unknown1
M. TahirAffiliation unknown1
W WahyuniAffiliation unknown1
Aty WidyawaruyantiAffiliation unknown1
Achmad Fuad HafidAffiliation unknown1
Wiwied EkasariAffiliation unknown1
Andryani NingsiAffiliation unknown1
Dwi Nur SaktianiAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/pharmauho/oai, first harvested 30 Okt 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Uji Toksisitas Akut Ekstrak Metanol Daun Keji Beling (Strobilanthes crispus BI.), Batang dan Bunga Jarak Tintir (Jatropha multifida L.) terhadap Larva Artemia salina Leach dengan Metode Brine Shrimp Lethality Test (BSLT)</dc:title>
	<dc:creator>Hamsidi, Rini</dc:creator>
	<dc:creator>Wahyuni, Wahyuni</dc:creator>
	<dc:creator>Sani, Asrul</dc:creator>
	<dc:description xml:lang="en-US">Research on the acute toxicity test of methanol extracts of keji beling leaves (Strobilanthes crispus BI.), stems and flowers of jarak tintir (Jatropha multifida L.) against Artemia salina Leach larvae using Brine Shrimp Lethality Test method (BSLT) had been carried out. The purpose of this study was to determine the potency of acute toxicity of methanol extract which were shown by LC50 value. In this research, the sample methanol were obtained from a previous research. Acute toxicity tests was conducted to determine the LC50 values of plant extracts according to the method of Brine Shrimp Lethality Test. Results of the research showed methanol extract of keji beling leaves were not toxic with LC50 value 4427,95 μg/mL, meanwhile stems and flowers of jarak tintir had low toxicity with LC50 225,09 and 253,26 μg/mL, respectively. The value of LC50 influenced by the content of secondary metabolites in plants.Keywords : Acute toxicity test, Brine Shrimp Lethality Test, LC50, J. multifida, S. crispus</dc:description>
	<dc:publisher xml:lang="en-US">Fakultas Farmasi Universitas Halu Oleo</dc:publisher>
	<dc:contributor xml:lang="en-US"></dc:contributor>
	<dc:date>2015-04-12</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
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	<dc:identifier>https://ojs.uho.ac.id/index.php/pharmauho/article/view/3456</dc:identifier>
	<dc:identifier>10.33772/pharmauho.v1i1.3456</dc:identifier>
	<dc:source xml:lang="en-US">Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan; Vol 1, No 1 (2015): Pharmauho</dc:source>
	<dc:source>2715-4181</dc:source>
	<dc:source>10.33772/pharmauho.v1i1</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ojs.uho.ac.id/index.php/pharmauho/article/view/3456/2610</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2018 Pharmauho</dc:rights>
</oai_dc:dc>