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Aktivitas Antioksidan Senyawa Asam 5(E)-Eikosenoat dari Batang Tanaman Polygonum pulchrum Bl

Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan · Vol. 1 No. 2 (2015)

DOI
10.33772/pharmauho.v1i2.3462
ISSN
2715-4181
Published
2015-09-16
Publisher
Fakultas Farmasi Universitas Halu Oleo
Language
eng

Abstract

Isolation and identification of secondary metabolite stem bark of Polygonum pulchrum and its antioxidant activity were done. Extraction was performed by maceration using methanol solvent. The separation and purification obtained by using vacuum liquid chromatography (VLC), radial chromatography (RC) and monitored by thin layer chromatography (TLC). Identification of isolated compounds determined by spectroscopy method i.e. FT-IR, 1D-NMR (1H, 13C-NMR and DEPT) and 2-D NMR (HMQC and HMBC). White solid compound was isolated and characterized as 5(E)-eicosenoic acid. Antioxidant was analyzed towards DPPH (1,1-diphenyl-picrilhydrazil). The compound showed that has antioxidant potency with IC50 value at 348.10 µM.Keywords: Polygonum pulchrum, 5(E)-eicosenoic acid, antimicrobial, antioxidant

Collaboration network of the authors

40 authors · 141 co-authorship links · showing the 40 most connected

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  • Universitas Halu Oleo
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
W WahyuniAffiliation unknown7
S SahidinAffiliation unknown5
Wahyuni WahyuniAffiliation unknown5
Nur Illiyyin AkibAffiliation unknown4
Adryan FristiohadyAffiliation unknown4
Henny KasmawatiUniversitas Halu Oleo3
S SabarudinAffiliation unknown3
Musadar MappasombaAffiliation unknown3
Vica AspadiahAffiliation unknown3
Rina AndrianiAffiliation unknown3
Analuddin AnaluddinUniversitas Halu Oleo2
Fadhliyah MalikAffiliation unknown2
Mentarry BafadalAffiliation unknown2
Asrul SaniAffiliation unknown2
Haristan HaristanAffiliation unknown1
Wahyu Hendrawan TulungiAffiliation unknown1
LOAN RamadhanAffiliation unknown1
Suryani SuryaniUniversitas Halu Oleo1
Nurlena IkawatiAffiliation unknown1
Ardiyanti ArdiyantiAffiliation unknown1
Nurhayani HMAffiliation unknown1
Muhammad Juharisman SaputraAffiliation unknown1
Wa BaaneAffiliation unknown1
Andi SeptianaUniversitas Halu Oleo1
Jamili JamiliAffiliation unknown1
Asrun BudiatmaAffiliation unknown1
Musdalifa MusdalifaAffiliation unknown1
wiwin WiwinAffiliation unknown1
Ari SartinahUniversitas Halu Oleo1
Mesi LeoritaAffiliation unknown1
Sandra Aulia MardikasariAffiliation unknown1
Mustakim HamidAffiliation unknown1
Didi Dharmadi HasanuddinAffiliation unknown1
Indah MawarniAffiliation unknown1
Baru SadarunAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/pharmauho/oai, first harvested 30 Okt 2026, last seen 30 Okt 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Aktivitas Antioksidan Senyawa Asam 5(E)-Eikosenoat dari Batang Tanaman Polygonum pulchrum Bl</dc:title>
	<dc:creator>Malaka, Muhammad Hajrul</dc:creator>
	<dc:creator>Yodha, Agung Wibawa Mahatva</dc:creator>
	<dc:creator>Azhar, Muhammad</dc:creator>
	<dc:creator>Hamsidi, Rini</dc:creator>
	<dc:creator>Sahidin, Sahidin</dc:creator>
	<dc:description xml:lang="en-US">Isolation and identification of secondary metabolite stem bark of Polygonum pulchrum and its antioxidant activity were done. Extraction was performed by maceration using methanol solvent. The separation and purification obtained by using vacuum liquid chromatography (VLC), radial chromatography (RC) and monitored by thin layer chromatography (TLC). Identification of isolated compounds determined by spectroscopy method i.e. FT-IR, 1D-NMR (1H, 13C-NMR and DEPT) and 2-D NMR (HMQC and HMBC). White solid compound was isolated and characterized as 5(E)-eicosenoic acid. Antioxidant was analyzed towards DPPH (1,1-diphenyl-picrilhydrazil). The compound showed that has antioxidant potency with IC50 value at 348.10 µM.Keywords: Polygonum pulchrum, 5(E)-eicosenoic acid, antimicrobial, antioxidant </dc:description>
	<dc:publisher xml:lang="en-US">Fakultas Farmasi Universitas Halu Oleo</dc:publisher>
	<dc:contributor xml:lang="en-US"></dc:contributor>
	<dc:date>2015-09-16</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:type xml:lang="en-US"></dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ojs.uho.ac.id/index.php/pharmauho/article/view/3462</dc:identifier>
	<dc:identifier>10.33772/pharmauho.v1i2.3462</dc:identifier>
	<dc:source xml:lang="en-US">Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan; Vol 1, No 2 (2015): Pharmauho</dc:source>
	<dc:source>2715-4181</dc:source>
	<dc:source>10.33772/pharmauho.v1i2</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ojs.uho.ac.id/index.php/pharmauho/article/view/3462/2616</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2018 Pharmauho</dc:rights>
</oai_dc:dc>