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Efektivitas Gel Tepung Cacing Tanah (Lumbricus rubellus Hoff.) Sebagai Penyembuh Luka Sayat Pada Mencit (Mus muscullus L.)

BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research) · Vol. 9 No. 2 (2023) · pp. 59–68

DOI
10.33772/biowallacea.v9i2.25504
ISSN
2685-6360, 2355-6404
Published
2023-01-07
Publisher
University of Halu Oleo
Language
eng
License
creativecommons.org/licenses/by/4.0

Abstract

Cuts are wounds that occur due to being cut by a sharp instrument. Earthworms (Lumbricus rubellus Hoff.) contain antibacterial compounds, arachidonic acid and proteins that help the growth of skin tissue. The formulation in the form of a gel is easier to use and has soothing, moisturizing properties, and easily penetrates the skin so that it provides a healing effect. This study aims to determine the effect of earthworm flour gel on wound healing in mice (Mus muscullus L.). This type of research is an experimental study with a completely randomized design (CRD). A total of 20 male mice were divided into 5 groups, namely positive control (Kalmicetine 10%), negative control (without treatment), K1 (earthworm flour gel concentration 3%), K2 (earthworm flour gel concentration 4%) and K3 (earthworm flour gel with a concentration of 4%). earthworm flour 5% concentration). The results showed that the average length of time for wound healing for each group was 11.75 days or 282 hours for a 3% concentration, 11.25 days or 270 hours for a 4% concentration, and 11 days or 264 hours for a 5% concentration, compared to positive control (Kalmicetine). 10%) 12 days or 288 hours and negative control for 14 days or 336 hours. The results of the study concluded that earthworm (Lumbricus rubellus Hoff.) flour gel was effective in accelerating the healing of cuts.Keywords: Cuts, Lumbricus rubellus, gelAbstrakLuka sayat adalah luka yang terjadi karena teriris oleh instrument yang tajam. Cacing tanah (Lumbricus rubellus Hoff.) mengandung senyawa antibakteri, asam arakidonat dan protein yang membantu pertumbuhan jaringan kulit. Formulasi dalam bentuk gel lebih mudah digunakan dan mempunyai sifat yang menyejukan, melembabkan, dan mudah berpenetrasi pada kulit sehingga memberikan efek penyembuhan. Penelitian ini bertujuan untuk mengetahui pengaruh gel tepung cacing tanah terhadap penyembuhan luka sayat pada mencit (Mus muscullus L.). Jenis penelitian adalah penelitian eksperimental dengan metode rancangan acak lengkap (RAL). Sebanyak 20 ekor mencit jantan dibagi dalam 5 kelompok yaitu kontrol positif (Kalmicetine 10%), kontrol negatif (tanpa perlakuan), K1 (gel tepung cacing tanah konsentrasi 3%), K2 (gel tepung cacing tanah konsentrasi 4%) dan K3 (gel tepung cacing tanah konsentrasi 5%). Hasil penelitian menunjukkan bahwa rerata lama waktu penyembuhan luka setiap kelompok adalah 11,75 hari atau 282 jam untuk konsentrasi 3%, 11.25 hari atau 270 jam untuk konsentrasi 4%, dan 11 hari atau 264 jam untuk konsentrasi 5%, dibandingkan kontrol positif (Kalmicetine 10%) 12 hari atau 288 jam dan kontrol negatif selama 14 hari atau 336 jam. Hasil penelitian disimpulkan bahwa gel tepung cacing tanah (Lumbricus rubellus Hoff.) efektif dalam mempercepat penyembuhan luka sayat.Kata Kunci: Luka sayat, Lumbricus rubellus, gel

Collaboration network of the authors

40 authors · 104 co-authorship links · 5 across different organisations · showing the 40 most connected

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Universitas Halu Oleo
  • Universitas Syiah Kuala
  • Osaka City University
  • Institut Agama Islam Negeri Kendari
  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Namriah NamriahUniversitas Halu Oleo9
Sahta GintingUniversitas Halu Oleo8
Darwis DarwisUniversitas Halu Oleo8
SYAMSU ALAMAffiliation unknown4
Andi SeptianaUniversitas Halu Oleo3
Nurhayu MalikAffiliation unknown3
Khairul MunadiUniversitas Syiah Kuala2
Yunida YunidaUniversitas Syiah Kuala2
Halim HalimUniversitas Halu Oleo2
Sitti LeomoUniversitas Halu Oleo2
Kahirun KahirunUniversitas Halu Oleo2
Jamili JamiliAffiliation unknown2
Suriana SurianaAffiliation unknown2
Dwi Arinto AdiAffiliation unknown2
Tetsuo TsujiokaOsaka City University1
Analuddin AnaluddinUniversitas Halu Oleo1
F. S. RembonAffiliation unknown1
Asmuddin AsmuddinUniversitas Halu Oleo1
Dewi Nurhayati YusufUniversitas Halu Oleo1
NURMA ADEAffiliation unknown1
DILA PUSPITAAffiliation unknown1
Nunik Dwi YulianaAffiliation unknown1
Fransiscus RembonAffiliation unknown1
Nur ApriliantiAffiliation unknown1
Arsy Aysyah AnnasAffiliation unknown1
Fitmayanti FitmayantiAffiliation unknown1
Lukman YunusAffiliation unknown1
La Baco S.Affiliation unknown1
La Ode Santiaji BandeUniversitas Halu Oleo1
Gusnawaty HSUniversitas Halu Oleo1
Ernawati ErnawatiInstitut Agama Islam Negeri Kendari1
Gusni Sri NingsihAffiliation unknown1
Analuddin KangkusoAffiliation unknown1
Inda YaniAffiliation unknown1
Siska PratiwiAffiliation unknown1
Nufrianti NufriantiAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/wallacea/oai, first harvested 31 Okt 2026, last seen 31 Okt 2026.
Original metadata (oai_dc)
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	<dc:title xml:lang="en-US">Efektivitas Gel Tepung Cacing Tanah (Lumbricus rubellus Hoff.) Sebagai Penyembuh Luka Sayat Pada Mencit (Mus muscullus L.)</dc:title>
	<dc:creator>Harlis, Wa Ode</dc:creator>
	<dc:creator>Nasaruddin, Nasaruddin</dc:creator>
	<dc:creator>Nurhasana, Nurhasana</dc:creator>
	<dc:creator>Resman, Resman</dc:creator>
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	<dc:description xml:lang="en-US">Cuts are wounds that occur due to being cut by a sharp instrument. Earthworms (Lumbricus rubellus Hoff.) contain antibacterial compounds, arachidonic acid and proteins that help the growth of skin tissue. The formulation in the form of a gel is easier to use and has soothing, moisturizing properties, and easily penetrates the skin so that it provides a healing effect. This study aims to determine the effect of earthworm flour gel on wound healing in mice (Mus muscullus L.). This type of research is an experimental study with a completely randomized design (CRD). A total of 20 male mice were divided into 5 groups, namely positive control (Kalmicetine 10%), negative control (without treatment), K1 (earthworm flour gel concentration 3%), K2 (earthworm flour gel concentration 4%) and K3 (earthworm flour gel with a concentration of 4%). earthworm flour 5% concentration). The results showed that the average length of time for wound healing for each group was 11.75 days or 282 hours for a 3% concentration, 11.25 days or 270 hours for a 4% concentration, and 11 days or 264 hours for a 5% concentration, compared to positive control (Kalmicetine). 10%) 12 days or 288 hours and negative control for 14 days or 336 hours. The results of the study concluded that earthworm (Lumbricus rubellus Hoff.) flour gel was effective in accelerating the healing of cuts.Keywords: Cuts, Lumbricus rubellus, gelAbstrakLuka sayat adalah luka yang terjadi karena teriris oleh instrument yang tajam. Cacing tanah (Lumbricus rubellus Hoff.) mengandung senyawa antibakteri, asam arakidonat dan protein yang membantu pertumbuhan jaringan kulit. Formulasi dalam bentuk gel lebih mudah digunakan dan mempunyai sifat yang menyejukan, melembabkan, dan mudah berpenetrasi pada kulit sehingga memberikan efek penyembuhan. Penelitian ini bertujuan untuk mengetahui pengaruh gel tepung cacing tanah  terhadap penyembuhan luka sayat pada mencit (Mus muscullus L.). Jenis penelitian adalah penelitian eksperimental dengan metode rancangan acak lengkap (RAL).  Sebanyak 20 ekor mencit jantan dibagi dalam 5 kelompok yaitu kontrol positif (Kalmicetine 10%), kontrol negatif (tanpa perlakuan), K1 (gel tepung cacing tanah konsentrasi 3%), K2 (gel tepung cacing tanah konsentrasi 4%) dan K3 (gel tepung cacing tanah konsentrasi 5%). Hasil penelitian menunjukkan bahwa rerata lama waktu penyembuhan luka setiap kelompok adalah 11,75 hari atau 282 jam untuk konsentrasi 3%, 11.25 hari atau 270 jam untuk konsentrasi 4%, dan 11 hari atau 264 jam untuk konsentrasi 5%, dibandingkan kontrol positif  (Kalmicetine 10%) 12 hari atau 288 jam dan kontrol negatif selama 14 hari atau 336 jam. Hasil penelitian disimpulkan bahwa gel tepung cacing tanah (Lumbricus rubellus Hoff.) efektif dalam mempercepat penyembuhan luka sayat.Kata Kunci: Luka sayat, Lumbricus rubellus, gel</dc:description>
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	<dc:date>2023-01-07</dc:date>
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	<dc:source xml:lang="en-US">BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research); Vol 9, No 2 (2022): Biodiversitas Wallacea; 59-68</dc:source>
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	<dc:language>eng</dc:language>
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	<dc:rights xml:lang="en-US">Copyright (c) 2022 BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research)</dc:rights>
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