EFEKTIVITAS EKSTRAK RIMPANG JAHE PUTIH (Zingiber officinale var. Amarum) SEBAGAI ANTIFERTILITAS TERHADAP KEBUNTINGAN MENCIT (Mus musculus L.) TAHAP PRAIMPLANTASI

Harlis, Wa Ode; Malik, Nurhayu; Nufrianti, Nufrianti

doi:10.33772/biowallacea.v5i1.4595

Jurnal

EFEKTIVITAS EKSTRAK RIMPANG JAHE PUTIH (Zingiber officinale var. Amarum) SEBAGAI ANTIFERTILITAS TERHADAP KEBUNTINGAN MENCIT (Mus musculus L.) TAHAP PRAIMPLANTASI

BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research) · Vol. 5 No. 1 (2018) · pp. 761–772

DOI: 10.33772/biowallacea.v5i1.4595
ISSN: 2685-6360, 2355-6404
Published: 2018-04-28
Publisher: University of Halu Oleo
Language: eng

Abstract

ABSTRAKTujuan penelitian ini untuk melihat efektivitas ekstrak rimpang jahe putih (Zingiber officinale var. Amarum) sebagai antifertilitas terhadap kebuntingan mencit (Mus musculus L.) tahap praimplantasi. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan. 16 ekor mencit betina berat 20-30 gr berumur 2-3 bulan dibagi kedalam 4 kelompok yaitu; K1 (Aquades), K2 (0,7 mg/g bb), K3 (1,4 mg/g bb), dan K4 (2,8 mg/g bb) ekstrak. Pemberian Ekstrak diberikan secara oral sebanyak 0,5 ml/ekor/hari pada kebuntingan hari ke-0 sampai ke-3. Mencit dipelihara sampai hari kebuntingan ke-18. Mencit dikorbankan dan dibedah, selanjutnya diamati parameter kebuntingan tahap praimplantasi. Hasil penelitian menunjukkan bahwa ekstrak rimpang jahe putih menurunkan persentase implantasi yaitu K1 (0,90%), K2 (0,39%), K3. Menurunkan persentase embrio resorbsi yaitu K1 (0%), K2 (0%), K3. Menurunkan persentase fetus hidup yaitu K1 (0,90%), K2 (0,35%), K3. Serta meningkatkan persentase fetus mati K1 (0%), K2 (0,04%) K3 dan pada keempat parameter untuk K4 tidak ditemukan fetus, Ekstrak juga meningkatkan persentase kehilangan gestasi yaitu K1 (0,12%), K2 (0,60%), K3 (1%)dan K4 (1%). Kata kunci: Ekstrak rimpang jahe putih, Kebuntingan tahap praimplantasi ABSTRACT The purpose of this study was to see the effectiveness of white ginger rhizome extract (Zingiber officinale var. Amarum) as an antifertility on pregnancy in the preimplantation stage of mice (Mus musculus L.). This study uses a Completely Randomized Design (CRD) consisting of 4 treatments. 16 female mice weighing 20-30 grams aged 2-3 months were divided into 4 groups, namely; K1 (Aquades), K2 (0.7 mg / g bb), K3 (1.4 mg / g bb), and K4 (2.8 mg / g bb) extract. The administration of the extract was administered orally as much as 0.5 ml / head / day in the 0 to 3 day pregnancy. Mice are maintained until the 18th pregnancy day. Mice were sacrificed and dissected, then the preimplantation stage pregnancy parameters were observed. The results showed that the white ginger rhizome extract reduced the percentage of implantation, namely K1 (0.90%), K2 (0.39%), K3. Reducing the percentage of resorbsi embryos, namely K1 (0%), K2 (0%), K3. Reducing the percentage of live fetuses, namely K1 (0.90%), K2 (0.35%), K3. As well as increasing the percentage of dead fetuses K1 (0%), K2 (0.04%) K3 and in the fourth parameter for K4 no fetus was found, the extract also increased the percentage of gestational loss, namely K1 (0.12%), K2 (0.60% ), K3 (1%) and K4 (1%). Keywords: White ginger rhizome extract, preimplantation stage pregnancy

Collaboration network of the authors

32 authors · 75 co-authorship links · 4 across different organisations

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Universitas Halu Oleo
Universitas Gadjah Mada
Universitas Syiah Kuala
Sriwijaya University
Institut Agama Islam Negeri Kendari
Universitas Muhammadiyah Parepare
Affiliation unknown

Different organisations
Same organisation
Affiliation unknown
Thicker line = more joint articles · bigger circle = more articles

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Co-author	Organisation	Joint articles
Salahuddin Salahuddin	Universitas Gadjah Mada	5
Andi Septiana	Universitas Halu Oleo	3
Jamili Jamili	Affiliation unknown	2
Nasaruddin Nasaruddin	Universitas Syiah Kuala	2
Suriana Suriana	Affiliation unknown	2
Dwi Arinto Adi	Affiliation unknown	2
Inda Yani	Affiliation unknown	2
Analuddin Analuddin	Universitas Halu Oleo	1
Hariyanto Hariyanto	Affiliation unknown	1
Fitmayanti Fitmayanti	Affiliation unknown	1
Indrawati Indrawati	Sriwijaya University	1
St. Mantasia	Affiliation unknown	1
Yani Taufik	Affiliation unknown	1
Wa Ode Nur Niya	Affiliation unknown	1
Musadar Mappasomba	Affiliation unknown	1
Muhammad Fadhil Pallatje	Affiliation unknown	1
Victor Braganca	Affiliation unknown	1
La Ode Ali Amani	Affiliation unknown	1
Musadar Musadar	Affiliation unknown	1
Fidar Susilawati	Affiliation unknown	1
Resman Resman	Affiliation unknown	1
Nurhasana Nurhasana	Universitas Halu Oleo	1
Ernawati Ernawati	Institut Agama Islam Negeri Kendari	1
Siska Pratiwi	Affiliation unknown	1
Arjuni Arjuni	Affiliation unknown	1
Amirullah Amirullah	Affiliation unknown	1
Eis Nurhiliya	Affiliation unknown	1
Jusrianti Jusrianti	Universitas Muhammadiyah Parepare	1
Sitti Wirdhana Ahmad	Affiliation unknown	1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ojs.uho.ac.id/index.php/wallacea/oai, first harvested 31 Okt 2026, last seen 1 Nov 2026.

Original metadata (oai_dc)

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	<dc:title xml:lang="en-US">EFEKTIVITAS  EKSTRAK RIMPANG  JAHE PUTIH (Zingiber officinale var. Amarum) SEBAGAI ANTIFERTILITAS TERHADAP KEBUNTINGAN MENCIT (Mus musculus L.) TAHAP PRAIMPLANTASI</dc:title>
	<dc:creator>Harlis, Wa Ode</dc:creator>
	<dc:creator>Malik, Nurhayu</dc:creator>
	<dc:creator>Nufrianti, Nufrianti</dc:creator>
	<dc:description xml:lang="en-US">ABSTRAKTujuan penelitian ini untuk melihat efektivitas ekstrak rimpang jahe putih (Zingiber officinale var. Amarum) sebagai antifertilitas terhadap kebuntingan mencit (Mus musculus L.) tahap praimplantasi. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan. 16 ekor mencit betina berat 20-30 gr  berumur 2-3 bulan dibagi kedalam 4 kelompok  yaitu;  K1 (Aquades), K2 (0,7 mg/g bb), K3 (1,4 mg/g bb), dan K4 (2,8 mg/g bb) ekstrak. Pemberian Ekstrak diberikan secara oral sebanyak 0,5 ml/ekor/hari pada kebuntingan hari ke-0 sampai ke-3. Mencit dipelihara sampai hari kebuntingan ke-18. Mencit dikorbankan dan dibedah, selanjutnya diamati parameter kebuntingan tahap praimplantasi. Hasil penelitian menunjukkan bahwa ekstrak rimpang jahe putih menurunkan persentase implantasi yaitu K1 (0,90%), K2 (0,39%), K3. Menurunkan persentase embrio resorbsi yaitu K1 (0%), K2 (0%), K3. Menurunkan persentase fetus hidup yaitu K1 (0,90%), K2 (0,35%), K3. Serta meningkatkan persentase fetus mati K1 (0%), K2 (0,04%) K3 dan pada keempat parameter untuk K4 tidak ditemukan fetus, Ekstrak juga meningkatkan persentase kehilangan gestasi yaitu K1 (0,12%), K2 (0,60%), K3 (1%)dan K4 (1%). Kata kunci : Ekstrak rimpang jahe putih, Kebuntingan tahap praimplantasi ABSTRACT The purpose of this study was to see the effectiveness of white ginger rhizome extract (Zingiber officinale var. Amarum) as an antifertility on pregnancy in the preimplantation stage of mice (Mus musculus L.). This study uses a Completely Randomized Design (CRD) consisting of 4 treatments. 16 female mice weighing 20-30 grams aged 2-3 months were divided into 4 groups, namely; K1 (Aquades), K2 (0.7 mg / g bb), K3 (1.4 mg / g bb), and K4 (2.8 mg / g bb) extract. The administration of the extract was administered orally as much as 0.5 ml / head / day in the 0 to 3 day pregnancy. Mice are maintained until the 18th pregnancy day. Mice were sacrificed and dissected, then the preimplantation stage pregnancy parameters were observed. The results showed that the white ginger rhizome extract reduced the percentage of implantation, namely K1 (0.90%), K2 (0.39%), K3. Reducing the percentage of resorbsi embryos, namely K1 (0%), K2 (0%), K3. Reducing the percentage of live fetuses, namely K1 (0.90%), K2 (0.35%), K3. As well as increasing the percentage of dead fetuses K1 (0%), K2 (0.04%) K3 and in the fourth parameter for K4 no fetus was found, the extract also increased the percentage of gestational loss, namely K1 (0.12%), K2 (0.60% ), K3 (1%) and K4 (1%). Keywords: White ginger rhizome extract, preimplantation stage pregnancy</dc:description>
	<dc:publisher xml:lang="en-US">University of Halu Oleo</dc:publisher>
	<dc:contributor xml:lang="en-US">University of Halu Oleo Kendari</dc:contributor>
	<dc:date>2018-04-28</dc:date>
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	<dc:identifier>https://ojs.uho.ac.id/index.php/wallacea/article/view/4595</dc:identifier>
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	<dc:source xml:lang="en-US">BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research); Vol 5, No 1 (2018): Sains  Biodiversitas Wallacea; 761-772</dc:source>
	<dc:source>2685-6360</dc:source>
	<dc:source>2355-6404</dc:source>
	<dc:source>10.33772/biowallacea.v5i1</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ojs.uho.ac.id/index.php/wallacea/article/view/4595/3493</dc:relation>
	<dc:relation>https://ojs.uho.ac.id/index.php/wallacea/article/downloadSuppFile/4595/253</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2018 Jurnal BioWallacea</dc:rights>
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