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Uji Aktivitas Sitotoksik dan Analisis Fitokimia Ekstrak Etanol Daun Sampare (Glochidion sp.)

JURNAL BIOLOGI PAPUA · Vol. 9 No. 2 (2018) · pp. 49–54

DOI
10.31957/jbp.112
ISSN
2503-0450, 2086-3314
Published
2018-05-14
Publisher
Jurusan Biologi FMIPA Universitas Cenderawasih
Language
eng

Abstract

Sampare (Glochidion sp., Family: Phyllantaceae) is a plant which grows dominant in Biak, Papua. Based on the local wisdom of the community, by hereditary, it can be used as an herbal medicine to treat the malaria disease. This study aims to determine the toxicity of LC50 and to know the phytochemical compounds of extracted leaf of Glochidion sp using ethanol. The Brine Shrimp Lethality Test (BSLT) and phytochemical screening using reagent chemical substance methods were used in this research. The results of this study can be concluded that the toxicity of extracted leaf of Glochidion sp. using ethanol was low, with LC50 = 758.58 ppm and the results of phytochemical analysis showed the existence of the content of alkaloids, flavonoids, saponins, tannins and quinones. But, the steroids and triterpenoids could not be found in the extracted leaf of Glochidion sp using ethanol. Therefore, for further research is needed to isolate the bioactive compounds and in vivo test on the plasmodium, which cause the malaria disease. Key words: Glochidion sp., malaria desease, Brine Shrimp Lethality Test (BSLT), LC50, phytochemical analysis

Collaboration network of the authors

29 authors · 72 co-authorship links

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Co-authorOrganisationJoint articles
Ervina IndrayaniAffiliation unknown3
Maklon WarpurAffiliation unknown2
Puguh SujartaAffiliation unknown2
Suharno SuharnoAffiliation unknown2
Modustriati P. MardanyAffiliation unknown2
Zainal A. WasarakaAffiliation unknown2
Ign Joko SuyonoAffiliation unknown2
Kalep SegenilAffiliation unknown1
Laila HanumAffiliation unknown1
Laksmindra FitriaAffiliation unknown1
Rury EprilurahmanAffiliation unknown1
Paul J. KawatuAffiliation unknown1
Sismindari SismindariAffiliation unknown1
Apianus KilunggaAffiliation unknown1
Yuliana H. RumsarwirAffiliation unknown1
Agustriani WarpurAffiliation unknown1
Lisye I. ZebuaAffiliation unknown1
Tomi A. NelamboAffiliation unknown1
Daniel LantangAffiliation unknown1
Ike G. SiregarAffiliation unknown1
Henderina J. KeiluhuAffiliation unknown1
Sarah YulianaAffiliation unknown1
Ronauli SilitongaAffiliation unknown1
Irma RahayuAffiliation unknown1
Farmawaty FarmawatyAffiliation unknown1
Rahmad S. BudiAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ejournal.uncen.ac.id/index.php/JBP/oai, first harvested 1 Nov 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Uji Aktivitas Sitotoksik dan Analisis Fitokimia Ekstrak Etanol Daun Sampare (Glochidion sp.)</dc:title>
	<dc:creator>Oktalia, Ganis</dc:creator>
	<dc:creator>Chrystomo, Linus Y.</dc:creator>
	<dc:creator>Karim, Aditya K.</dc:creator>
	<dc:description xml:lang="en-US">Sampare (Glochidion sp., Family: Phyllantaceae) is a plant which grows dominant in Biak, Papua. Based on the local wisdom of the community, by hereditary, it can be used as an herbal medicine to treat the malaria disease. This study aims to determine the toxicity of LC50 and to know the phytochemical compounds of extracted leaf of Glochidion sp using ethanol. The Brine Shrimp Lethality Test (BSLT) and phytochemical screening using reagent chemical substance methods were used in this research. The results of this study can be concluded that the toxicity of extracted leaf of Glochidion sp. using ethanol was low, with LC50 = 758.58 ppm and the results of phytochemical analysis showed the existence of the content of alkaloids, flavonoids, saponins, tannins and quinones. But, the steroids and triterpenoids could not be found in the extracted leaf of Glochidion sp using ethanol. Therefore, for further research is needed to isolate the bioactive compounds and in vivo test on the plasmodium, which cause the malaria disease. Key words: Glochidion sp., malaria desease, Brine Shrimp Lethality Test (BSLT), LC50, phytochemical analysis</dc:description>
	<dc:publisher xml:lang="en-US">Jurusan Biologi FMIPA Universitas Cenderawasih</dc:publisher>
	<dc:date>2018-05-14</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.uncen.ac.id/index.php/JBP/article/view/112</dc:identifier>
	<dc:identifier>10.31957/jbp.112</dc:identifier>
	<dc:source xml:lang="en-US">JURNAL BIOLOGI PAPUA; Vol. 9 No. 2 (2017); 49-54</dc:source>
	<dc:source xml:lang="id-ID">Jurnal Biologi Papua; Vol 9 No 2 (2017); 49-54</dc:source>
	<dc:source>2503-0450</dc:source>
	<dc:source>2086-3314</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.uncen.ac.id/index.php/JBP/article/view/112/106</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2018 JURNAL BIOLOGI PAPUA</dc:rights>
</oai_dc:dc>