Human papillomavirus (HPV) is a significant source of morbidity and mortality worldwide. The primary risk factors for aquiring HPV are generally associated with sexual activity. Â Evidence suggest that condoms provide some protection against infection and disease progression, but any genital contact is sufficient for HPV transmission. Â Having more than one sexual partner often result in HPV infection. Â All sexually active adolescents are at high risk for aquiring HPV. Â Persistent infection with high-risk HPV types (e.g HPV 16 or 18) is considered necessary for the development cervical cancer. Â Most infection are asymptomatic and are efficiently cleared by he immune system. Â The lesions that caused by HPV can regress in adolescent and young adult women. Â A small percentage of adolescents will develop precancerous lesions that may progress to invasive cervical cancer. Â Adolescents should be given appropriate education about HPV and the dangers associated with infection. Â Vaccination for HPV infection should be given for presexually active children and adolescents.Key words: human papilloma virus, adolescent, cervical cancer, vaccination.Â
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