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Skrining Senyawa Kimia dan Uji Aktivitas Sitotoksik Ekstrak Etanol Teripang Kridou Bintik (Bohadschia argus Jeager) Asal Pantai Harlem Kabupaten Jayapura, Papua

JURNAL BIOLOGI PAPUA · Vol. 11 No. 1 (2019) · pp. 12–17

DOI
10.31957/jbp.633
ISSN
2503-0450, 2086-3314
Published
2019-05-29
Publisher
Jurusan Biologi FMIPA Universitas Cenderawasih
Language
eng

Abstract

The Bohadschia argus Jeager contains bioactive compounds that have the potential as antibiotics, antibacterial, antitumor, anticoagulants and anesthetics and alleviate cancer. This study aims to determine the content of chemical compounds group and to test the cytotoxic activity of ethanol extract of Bohadschia argus Jeager. The method for determining the group of chemical compounds was used the color reaction and precipitation using chemical reagents. The method for testing cytotoxic activity using the Brine Shimp Lethality Test (BSLT), this method commonly was used to test the safety of the use of natural ingredients as traditional medicine. The results of screening of the chemical compound group of  Bohadschia argus Jeager extract showed that the extract contained a lot of alkaloids secondary metabolites and few saponins. The results of testing of cytotoxic activity showed LC50 value of 878.22 ppm. Base on the results of this study it can be concluded that the ethanol extract of Bohadschia argus Jeager has significant cytotoxic activity against Artemia salina Leach, so it can be considered as a chemotherapeutic agent.   Key words: Screening, chemical compounds, ethanol extract, B. argus, BSLT.Â

Collaboration network of the authors

40 authors · 134 co-authorship links · showing the 40 most connected

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Co-authorOrganisationJoint articles
Suharno SuharnoAffiliation unknown13
Farmawaty FarmawatyAffiliation unknown10
Irma RahayuAffiliation unknown6
Henderite L. OheeAffiliation unknown4
Vita PurnamasariAffiliation unknown4
Aditya K. KarimAffiliation unknown3
Gerardinalia NgamelubunAffiliation unknown3
Maklon WarpurAffiliation unknown2
Septriyanto DirgantaraAffiliation unknown2
Suwito SuwitoAffiliation unknown2
Maria Ludia SimonapendiAffiliation unknown2
Suriani Br SurbaktiAffiliation unknown2
Mesak MantekAffiliation unknown2
Ervina IndrayaniAffiliation unknown2
Modustriati P. MardanyAffiliation unknown1
Kalep SegenilAffiliation unknown1
Ganis OktaliaAffiliation unknown1
Zainal A. WasarakaAffiliation unknown1
Erlani RaharengAffiliation unknown1
Joane J. AnsakaAffiliation unknown1
Novela H. KorwaAffiliation unknown1
Yuliana H. RumsarwirAffiliation unknown1
Agustriani WarpurAffiliation unknown1
Lisye I. ZebuaAffiliation unknown1
Tomi A. NelamboAffiliation unknown1
Leonardo A. NumberiAffiliation unknown1
Roma M. ManaluAffiliation unknown1
Marseline G. MailisaAffiliation unknown1
Irene SuebuAffiliation unknown1
Wehelmina LahalloAffiliation unknown1
Daniel LantangAffiliation unknown1
Ike G. SiregarAffiliation unknown1
Norce MoteAffiliation unknown1
Michael A. RiceAffiliation unknown1
Suriani SurbaktiAffiliation unknown1
Henderina J. KeiluhuAffiliation unknown1
Sarah YulianaAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ejournal.uncen.ac.id/index.php/JBP/oai, first harvested 1 Nov 2026, last seen 1 Nov 2026.
Original metadata (oai_dc)
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	<dc:title xml:lang="en-US">Skrining Senyawa Kimia dan Uji Aktivitas Sitotoksik Ekstrak Etanol Teripang Kridou Bintik (Bohadschia argus Jeager) Asal Pantai Harlem Kabupaten Jayapura, Papua</dc:title>
	<dc:creator>Kilungga, Apianus</dc:creator>
	<dc:creator>Chrystomo, Linus Y.</dc:creator>
	<dc:creator>Sujarta, Puguh</dc:creator>
	<dc:description xml:lang="en-US">The Bohadschia argus Jeager contains bioactive compounds that have the potential as antibiotics, antibacterial, antitumor, anticoagulants and anesthetics and alleviate cancer. This study aims to determine the content of chemical compounds group and to test the cytotoxic activity of ethanol extract of Bohadschia argus Jeager. The method for determining the group of chemical compounds was used the color reaction and precipitation using chemical reagents. The method for testing cytotoxic activity using the Brine Shimp Lethality Test (BSLT), this method commonly was used to test the safety of the use of natural ingredients as traditional medicine. The results of screening of the chemical compound group of  Bohadschia argus Jeager extract showed that the extract contained a lot of alkaloids secondary metabolites and few saponins. The results of testing of cytotoxic activity showed LC50 value of 878.22 ppm. Base on the results of this study it can be concluded that the ethanol extract of Bohadschia argus Jeager has significant cytotoxic activity against Artemia salina Leach, so it can be considered as a chemotherapeutic agent.   Key words: Screening, chemical compounds, ethanol extract, B. argus, BSLT. </dc:description>
	<dc:publisher xml:lang="en-US">Jurusan Biologi FMIPA Universitas Cenderawasih</dc:publisher>
	<dc:date>2019-05-29</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.uncen.ac.id/index.php/JBP/article/view/633</dc:identifier>
	<dc:identifier>10.31957/jbp.633</dc:identifier>
	<dc:source xml:lang="en-US">JURNAL BIOLOGI PAPUA; Vol. 11 No. 1 (2019); 12-17</dc:source>
	<dc:source xml:lang="id-ID">Jurnal Biologi Papua; Vol 11 No 1 (2019); 12-17</dc:source>
	<dc:source>2503-0450</dc:source>
	<dc:source>2086-3314</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.uncen.ac.id/index.php/JBP/article/view/633/788</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2019 JURNAL BIOLOGI PAPUA</dc:rights>
</oai_dc:dc>