Jurnal
Skrining Senyawa Kimia dan Uji Aktivitas Sitotoksik Ekstrak Etanol Teripang Kridou Bintik (Bohadschia argus Jeager) Asal Pantai Harlem Kabupaten Jayapura, Papua
JURNAL BIOLOGI PAPUA · Vol. 11 No. 1 (2019) · pp. 12–17
- ISSN
- 2503-0450, 2086-3314
- Published
- 2019-05-29
- Publisher
- Jurusan Biologi FMIPA Universitas Cenderawasih
- Language
- eng
Abstract
The Bohadschia argus Jeager contains bioactive compounds that have the potential as antibiotics, antibacterial, antitumor, anticoagulants and anesthetics and alleviate cancer. This study aims to determine the content of chemical compounds group and to test the cytotoxic activity of ethanol extract of Bohadschia argus Jeager. The method for determining the group of chemical compounds was used the color reaction and precipitation using chemical reagents. The method for testing cytotoxic activity using the Brine Shimp Lethality Test (BSLT), this method commonly was used to test the safety of the use of natural ingredients as traditional medicine. The results of screening of the chemical compound group of  Bohadschia argus Jeager extract showed that the extract contained a lot of alkaloids secondary metabolites and few saponins. The results of testing of cytotoxic activity showed LC50 value of 878.22 ppm. Base on the results of this study it can be concluded that the ethanol extract of Bohadschia argus Jeager has significant cytotoxic activity against Artemia salina Leach, so it can be considered as a chemotherapeutic agent.   Key words: Screening, chemical compounds, ethanol extract, B. argus, BSLT.Â
Collaboration network of the authors
40 authors · 134 co-authorship links · showing the 40 most connected
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Show as table
| Co-author | Organisation | Joint articles |
|---|---|---|
| Suharno Suharno | Affiliation unknown | 13 |
| Farmawaty Farmawaty | Affiliation unknown | 10 |
| Irma Rahayu | Affiliation unknown | 6 |
| Henderite L. Ohee | Affiliation unknown | 4 |
| Vita Purnamasari | Affiliation unknown | 4 |
| Aditya K. Karim | Affiliation unknown | 3 |
| Gerardinalia Ngamelubun | Affiliation unknown | 3 |
| Maklon Warpur | Affiliation unknown | 2 |
| Septriyanto Dirgantara | Affiliation unknown | 2 |
| Suwito Suwito | Affiliation unknown | 2 |
| Maria Ludia Simonapendi | Affiliation unknown | 2 |
| Suriani Br Surbakti | Affiliation unknown | 2 |
| Mesak Mantek | Affiliation unknown | 2 |
| Ervina Indrayani | Affiliation unknown | 2 |
| Modustriati P. Mardany | Affiliation unknown | 1 |
| Kalep Segenil | Affiliation unknown | 1 |
| Ganis Oktalia | Affiliation unknown | 1 |
| Zainal A. Wasaraka | Affiliation unknown | 1 |
| Erlani Rahareng | Affiliation unknown | 1 |
| Joane J. Ansaka | Affiliation unknown | 1 |
| Novela H. Korwa | Affiliation unknown | 1 |
| Yuliana H. Rumsarwir | Affiliation unknown | 1 |
| Agustriani Warpur | Affiliation unknown | 1 |
| Lisye I. Zebua | Affiliation unknown | 1 |
| Tomi A. Nelambo | Affiliation unknown | 1 |
| Leonardo A. Numberi | Affiliation unknown | 1 |
| Roma M. Manalu | Affiliation unknown | 1 |
| Marseline G. Mailisa | Affiliation unknown | 1 |
| Irene Suebu | Affiliation unknown | 1 |
| Wehelmina Lahallo | Affiliation unknown | 1 |
| Daniel Lantang | Affiliation unknown | 1 |
| Ike G. Siregar | Affiliation unknown | 1 |
| Norce Mote | Affiliation unknown | 1 |
| Michael A. Rice | Affiliation unknown | 1 |
| Suriani Surbakti | Affiliation unknown | 1 |
| Henderina J. Keiluhu | Affiliation unknown | 1 |
| Sarah Yuliana | Affiliation unknown | 1 |
Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.