Melola Discovery

← Melola Discovery

Jurnal

Uji Efek Stimulansia Ekstrak Etil Asetat Kulit Kayu Akway (Drymis piperita) Asal Papua Pada Tikus (Ratus norvegicus) Jantan

JURNAL BIOLOGI PAPUA · Vol. 12 No. 1 (2020) · pp. 37–42

DOI
10.31957/jbp.969
ISSN
2503-0450, 2086-3314
Published
2020-03-05
Publisher
Jurusan Biologi FMIPA Universitas Cenderawasih
Language
eng

Abstract

Drymis sp. stem bark from Papua widely utilized by local people especially in Sougb Tribe from Sururey Distric Pegunungan Arfak West Papua, one of them is used to increase the stamina of the body. The aim of this study was to investigate the tonic effect of Drymis sp. stem bark of Ratus norvegicus. Ratatory exhaustion method was used to the tonic effect. Selected rats (30) were divided into 6 groups, each consisting of 5 rats. Tested extract was administrated oraly one dose to the rats. Group I, II and III was given the ethil acetat fraction of Drymis sp. stem bark 10mg/kg body weight, 30mg/kg body weight and 50mg/kg body weight consecutively. Group IV was given CMC-Na 0,5% (as negative control). Goup V was given caffein 15 mg/kg body weight (as positive control) and Group VI as a control. The total swimming period until exhaustion was measured and use as index of swimming capacity. Research result show that the highest dose 50 mg/body weight of the tested fraction the longer swimming time and with better stamina. The result of One Way ANOVA test showed that there was a significant difference between treatment group, followed by tukey test, tukey result obtained the ethil acetat fraction and negative control (CMC Na) showed that there was significant difference, and there is no real difference between between treatment group and positive control.   Key words: Drymis sp, Papua, tonic effect, rats. Â

Collaboration network of the authors

24 authors · 53 co-authorship links

Hover or tap a name to highlight its co-authors. Double-click to open the author's page.

  • Affiliation unknown
  • Different organisations
  • Same organisation
  • Affiliation unknown
  • Thicker line = more joint articles · bigger circle = more articles
Show as table
Co-authorOrganisationJoint articles
Elsye GunawanAffiliation unknown4
Maria T. NainggolanAffiliation unknown4
Verena AgustiniAffiliation unknown2
Deshinta S. NataliaAffiliation unknown1
Dirk Y.P. RuntuboiAffiliation unknown1
Agustina RubanAffiliation unknown1
Yati B. YuliatiAffiliation unknown1
Dadang SupriyatnaAffiliation unknown1
Rusnaeni RusnaeniAffiliation unknown1
Jane AwomAffiliation unknown1
Susan WopiAffiliation unknown1
Noviana HallikAffiliation unknown1
Risma PayungAffiliation unknown1
Supeni SufaatiAffiliation unknown1
Agnes E. MaryuniAffiliation unknown1
Nur F. BakriAffiliation unknown1
Maria J.S OlaAffiliation unknown1
Yuliana Rut YabansabraAffiliation unknown1
Anike BowaireAffiliation unknown1
Demas R. YaamAffiliation unknown1
Aira TirisAffiliation unknown1
Erpina S.M. NadeakAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ejournal.uncen.ac.id/index.php/JBP/oai, first harvested 1 Nov 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Uji Efek Stimulansia Ekstrak Etil Asetat Kulit Kayu Akway (Drymis piperita) Asal Papua Pada Tikus (Ratus norvegicus) Jantan</dc:title>
	<dc:creator>Pratiwi, Rani D.</dc:creator>
	<dc:creator>Simaremare, Eva S.</dc:creator>
	<dc:description xml:lang="en-US">Drymis sp. stem bark from Papua widely utilized by local people especially in Sougb Tribe from Sururey Distric Pegunungan Arfak West Papua, one of them is used to increase the stamina of the body. The aim of this study was to investigate the tonic effect of Drymis sp. stem bark of Ratus norvegicus. Ratatory exhaustion method was used to the tonic effect. Selected rats (30) were divided into 6 groups, each consisting of 5 rats. Tested extract was administrated oraly one dose to the rats. Group I, II and III was given the ethil acetat fraction of Drymis sp. stem bark 10mg/kg body weight, 30mg/kg body weight and 50mg/kg body weight consecutively. Group IV was given CMC-Na 0,5% (as negative control). Goup V was given caffein 15 mg/kg body weight (as positive control) and Group VI as a control. The total swimming period until exhaustion was measured and use as index of swimming capacity. Research result show that the highest dose 50 mg/body weight of the tested fraction the longer swimming time and with better stamina. The result of One Way ANOVA test showed that there was a significant difference between treatment group, followed by tukey test, tukey result obtained the ethil acetat fraction and negative control (CMC Na) showed that there was significant difference, and there is no real difference between between treatment group and positive control.   Key words: Drymis sp, Papua, tonic effect, rats.   </dc:description>
	<dc:publisher xml:lang="en-US">Jurusan Biologi FMIPA Universitas Cenderawasih</dc:publisher>
	<dc:date>2020-03-05</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.uncen.ac.id/index.php/JBP/article/view/969</dc:identifier>
	<dc:identifier>10.31957/jbp.969</dc:identifier>
	<dc:source xml:lang="en-US">JURNAL BIOLOGI PAPUA; Vol. 12 No. 1 (2020); 37-42</dc:source>
	<dc:source xml:lang="id-ID">Jurnal Biologi Papua; Vol 12 No 1 (2020); 37-42</dc:source>
	<dc:source>2503-0450</dc:source>
	<dc:source>2086-3314</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.uncen.ac.id/index.php/JBP/article/view/969/962</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2020 JURNAL BIOLOGI PAPUA</dc:rights>
</oai_dc:dc>