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Pengembangan Produk Minuman Tonikum Kulit Kayu Akway (Drymis piperita): Prospek Penambah Stamina Tubuh Secara In Vivo

JURNAL BIOLOGI PAPUA · Vol. 13 No. 1 (2021) · pp. 44–51

DOI
10.31957/jbp.1342
ISSN
2503-0450, 2086-3314
Published
2021-04-01
Publisher
Jurusan Biologi FMIPA Universitas Cenderawasih
Language
eng

Abstract

Akway bark (Drymis piperita) from Papua is widely used by local people in Arfak Mountains of West Papua to increase stamina. The purpose of this study was to determine the physical quality and tonic effects of Akway bark (bark tonic drink D. piperita) on mice (Mus musculus). The swimming resistance used to determine the tonic effect of mice (24 individuals) which divided into 6 groups. Group I was given water, group II tonic drink base, group III as positive control of 50 mg caffeine energy drinks, groups IV, V, and VI were given bark tonic drink 10mg /kg body weight, 30 mg/kg body weight, and 50mg /kg body weight respectively. The total period swimming until fatigue was measured and used as an index of swimming capacity. The results of  physical quality of the Akway bark tonic drink has a sweet and sour taste, with clear dark brown color, had distinctive aroma with pH of 4, and its volume was 100 ml with solubility deposits on day 21. The results of pre-clinical testing shown the highest dose was 50 mg/ weight swimming time 9.28 minutes and having better stamina. The next was with dose of 30 mg/kgBW, swimming for for 6.01 minutes and the last was dose of 10 mg /kgBW swimming for 3.23 minutes. The results of the one-way ANOVA test showed that it was significantly different between the 10 mg/kgBW, 30 mg/kgBW and 50 mg/kgBW groups. Key words: drink; D. piperita tonic; effect; mice; Papua.Â

Collaboration network of the authors

37 authors · 159 co-authorship links

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Co-authorOrganisationJoint articles
Eva S. SimaremareAffiliation unknown4
Rusnaeni RusnaeniAffiliation unknown3
Maria T. NainggolanAffiliation unknown2
Eva Susanty SimaremareAffiliation unknown2
Septriyanto DirgantaraAffiliation unknown2
Rani Dewi PratiwiAffiliation unknown2
Deshinta S. NataliaAffiliation unknown2
Risma PayungAffiliation unknown2
Nur F. BakriAffiliation unknown2
Verena AgustiniAffiliation unknown1
Jane AwomAffiliation unknown1
Susan WopiAffiliation unknown1
Ega RianaAffiliation unknown1
Nur F. BakrieAffiliation unknown1
Aris A.L. ToruanAffiliation unknown1
Felycitae E. AppaAffiliation unknown1
Maria J.S OlaAffiliation unknown1
RusnaeniAffiliation unknown1
Sarce M. SasarariAffiliation unknown1
Allowisya FutwembunAffiliation unknown1
Khoirul HudaAffiliation unknown1
Qonita A. NisaAffiliation unknown1
Yuliana R. YabansabraAffiliation unknown1
Tatang SutarmanAffiliation unknown1
Andre M. WorabaiAffiliation unknown1
Dimas A. SyafrudinAffiliation unknown1
Fadil M. Al RidhaAffiliation unknown1
Karlin MansumberAffiliation unknown1
Kristina I. RahailAffiliation unknown1
Marselina E. KotenAffiliation unknown1
Muhammad M. KhalilAffiliation unknown1
Ota M. RumainumAffiliation unknown1
Pitera WendaAffiliation unknown1
Sarhana R.A. SaidAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ejournal.uncen.ac.id/index.php/JBP/oai, first harvested 1 Nov 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
<oai_dc:dc xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/  http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
	<dc:title xml:lang="en-US">Pengembangan Produk Minuman Tonikum Kulit Kayu Akway (Drymis piperita): Prospek Penambah Stamina Tubuh Secara In Vivo</dc:title>
	<dc:creator>Hallik, Noviana</dc:creator>
	<dc:creator>Pratiwi, Rani D.</dc:creator>
	<dc:creator>Gunawan, Elsye</dc:creator>
	<dc:description xml:lang="en-US">Akway bark (Drymis piperita) from Papua is widely used by local people in Arfak Mountains of West Papua to increase stamina. The purpose of this study was to determine the physical quality and tonic effects of Akway bark (bark tonic drink D. piperita) on mice (Mus musculus). The swimming resistance used to determine the tonic effect of mice (24 individuals) which divided into 6 groups. Group I was given water, group II tonic drink base, group III as positive control of 50 mg caffeine energy drinks, groups IV, V, and VI were given bark tonic drink 10mg /kg body weight, 30 mg/kg body weight, and 50mg /kg body weight respectively. The total period swimming until fatigue was measured and used as an index of swimming capacity. The results of  physical quality of the Akway bark tonic drink has a sweet and sour taste, with clear dark brown color, had distinctive aroma with pH of 4, and its volume was 100 ml with solubility deposits on day 21. The results of pre-clinical testing shown the highest dose was 50 mg/ weight swimming time 9.28 minutes and having better stamina. The next was with dose of 30 mg/kgBW, swimming for for 6.01 minutes and the last was dose of 10 mg /kgBW swimming for 3.23 minutes. The results of the one-way ANOVA test showed that it was significantly different between the 10 mg/kgBW, 30 mg/kgBW and 50 mg/kgBW groups. Key words: drink; D. piperita tonic; effect; mice; Papua. </dc:description>
	<dc:publisher xml:lang="en-US">Jurusan Biologi FMIPA Universitas Cenderawasih</dc:publisher>
	<dc:date>2021-04-01</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.uncen.ac.id/index.php/JBP/article/view/1342</dc:identifier>
	<dc:identifier>10.31957/jbp.1342</dc:identifier>
	<dc:source xml:lang="en-US">JURNAL BIOLOGI PAPUA; Vol. 13 No. 1 (2021); 44-51</dc:source>
	<dc:source xml:lang="id-ID">Jurnal Biologi Papua; Vol 13 No 1 (2021); 44-51</dc:source>
	<dc:source>2503-0450</dc:source>
	<dc:source>2086-3314</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.uncen.ac.id/index.php/JBP/article/view/1342/1275</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2021 JURNAL BIOLOGI PAPUA</dc:rights>
</oai_dc:dc>