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Aktivitas Antikoagulan dari Tumbuhan Kayu Ular (Strychnos lucida R.Br.)

JURNAL BIOLOGI PAPUA · Vol. 14 No. 2 (2022) · pp. 129–136

DOI
10.31957/jbp.1494
ISSN
2503-0450, 2086-3314
Published
2022-10-15
Publisher
Jurusan Biologi FMIPA Universitas Cenderawasih
Language
eng

Abstract

The stem of the snakewood plant (Strychnos lucida) has been used empirically as a malaria drug, relieves fever, treats stomach pain, hemorrhoids, rheumatism, stroke symptoms, and improves blood circulation. Tannins as one of the secondary metabolites of snakewood stems contain gallic acid compounds which are known to thin the blood. The purpose of this study was to determine the anticoagulant activity of the ethanolic extract of snakewood stems on blood group samples, namely A, B, AB, and O. The method used for extraction was maceration, for testing anticoagulants used method modified Lee-White and blood smears, as well as for data analysis carried out descriptively. The results obtained by the Lee-White modification method on blood group samples were visually not clotting. For anticoagulant activity by blood smear method, it was shown that microscopically snakewood bark extract prevented the presence of blood clots which could be observed with unrelated blood cells, intact and separated from each other.Key words: S. lucida; Lee-White modification; blood smear; anticoagulants

Collaboration network of the authors

40 authors · 154 co-authorship links · showing the 40 most connected

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Co-authorOrganisationJoint articles
Eva Susanty SimaremareAffiliation unknown4
Septriyanto DirgantaraAffiliation unknown4
Rani Dewi PratiwiAffiliation unknown4
Rani D. PratiwiAffiliation unknown3
Nur F. BakriAffiliation unknown3
Mustika E. PratiwiAffiliation unknown2
Eva S. SimaremareAffiliation unknown2
Allowisya FutwembunAffiliation unknown2
Deshinta S. NataliaAffiliation unknown1
Verena AgustiniAffiliation unknown1
Jane AwomAffiliation unknown1
Susan WopiAffiliation unknown1
Noviana HallikAffiliation unknown1
Ega RianaAffiliation unknown1
Nur F. BakrieAffiliation unknown1
Risma PayungAffiliation unknown1
RusnaeniAffiliation unknown1
Sarce M. SasarariAffiliation unknown1
Claudius H.B. TobiAffiliation unknown1
Kevry SupraptiAffiliation unknown1
Andre A. BarusAffiliation unknown1
Artha M. SimanjuntakAffiliation unknown1
Agatha C.I. JedautAffiliation unknown1
Napita P.C. PasaribuAffiliation unknown1
Khoirul HudaAffiliation unknown1
Qonita A. NisaAffiliation unknown1
Andre M. WorabaiAffiliation unknown1
Dimas A. SyafrudinAffiliation unknown1
Fadil M. Al RidhaAffiliation unknown1
Karlin MansumberAffiliation unknown1
Kristina I. RahailAffiliation unknown1
Marselina E. KotenAffiliation unknown1
Muhammad M. KhalilAffiliation unknown1
Ota M. RumainumAffiliation unknown1
Pitera WendaAffiliation unknown1
Sarhana R.A. SaidAffiliation unknown1

Affiliations come from OpenAlex; journal OAI-PMH metadata carries none. Authors without an OpenAlex ID are matched by name, which can merge or split people.

Metadata source: OAI-PMH (metadata jurnal) https://ejournal.uncen.ac.id/index.php/JBP/oai, first harvested 1 Nov 2026, last seen 1 Nov 2026.
Original metadata (oai_dc) 
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	<dc:title xml:lang="en-US">Aktivitas Antikoagulan dari Tumbuhan Kayu Ular (Strychnos lucida R.Br.)</dc:title>
	<dc:creator>Gunawan, Elsye</dc:creator>
	<dc:creator>Toruan, Aris A.L.</dc:creator>
	<dc:creator>Rusnaeni, Rusnaeni</dc:creator>
	<dc:creator>Appa, Felycitae E.</dc:creator>
	<dc:description xml:lang="en-US">The stem of the snakewood plant (Strychnos lucida) has been used empirically as a malaria drug, relieves fever, treats stomach pain, hemorrhoids, rheumatism, stroke symptoms, and improves blood circulation. Tannins as one of the secondary metabolites of snakewood stems contain gallic acid compounds which are known to thin the blood. The purpose of this study was to determine the anticoagulant activity of the ethanolic extract of snakewood stems on blood group samples, namely A, B, AB, and O. The method used for extraction was maceration, for testing anticoagulants used method modified Lee-White and blood smears, as well as for data analysis carried out descriptively. The results obtained by the Lee-White modification method on blood group samples were visually not clotting. For anticoagulant activity by blood smear method, it was shown that microscopically snakewood bark extract prevented the presence of blood clots which could be observed with unrelated blood cells, intact and separated from each other.Key words: S. lucida; Lee-White modification; blood smear; anticoagulants</dc:description>
	<dc:publisher xml:lang="en-US">Jurusan Biologi FMIPA Universitas Cenderawasih</dc:publisher>
	<dc:date>2022-10-15</dc:date>
	<dc:type>info:eu-repo/semantics/article</dc:type>
	<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
	<dc:format>application/pdf</dc:format>
	<dc:identifier>https://ejournal.uncen.ac.id/index.php/JBP/article/view/1494</dc:identifier>
	<dc:identifier>10.31957/jbp.1494</dc:identifier>
	<dc:source xml:lang="en-US">JURNAL BIOLOGI PAPUA; Vol. 14 No. 2 (2022); 129-136</dc:source>
	<dc:source xml:lang="id-ID">Jurnal Biologi Papua; Vol 14 No 2 (2022); 129-136</dc:source>
	<dc:source>2503-0450</dc:source>
	<dc:source>2086-3314</dc:source>
	<dc:language>eng</dc:language>
	<dc:relation>https://ejournal.uncen.ac.id/index.php/JBP/article/view/1494/1994</dc:relation>
	<dc:rights xml:lang="en-US">Copyright (c) 2022 JURNAL BIOLOGI PAPUA</dc:rights>
</oai_dc:dc>